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Rgs6 regulator of G protein signaling 6 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101721173, updated on 8-Mar-2024

Summary

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Gene symbol
Rgs6
Gene description
regulator of G protein signaling 6
Locus tag
GW7_18557
See related
Ensembl:ENSHGLG00000012031
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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See Rgs6 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
22
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624734.1 (28830254..29436945, complement)

NW_004624734.1Genomic Context describing neighboring genes Neighboring gene DDB1 and CUL4 associated factor 4 Neighboring gene double PHD fingers 3 Neighboring gene ribosome production factor 2 homolog pseudogene Neighboring gene uncharacterized LOC110346323 Neighboring gene phospholipase D3 pseudogene Neighboring gene 60S ribosomal protein L31 pseudogene Neighboring gene uncharacterized LOC110346326 Neighboring gene uncharacterized LOC110346325

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624734 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
regulator of G-protein signaling 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624734.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    28830254..29436945 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004837270.3 → XP_004837327.1  regulator of G-protein signaling 6 isoform X1

    See identical proteins and their annotated locations for XP_004837327.1

    Conserved Domains (3) summary
    smart00224
    Location:258 → 319
    GGL; G protein gamma subunit-like motifs
    cd08737
    Location:328 → 452
    RGS_RGS6; Regulator of G protein signaling (RGS) domain found in the RGS6 protein
    cd04450
    Location:31 → 119
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...

  2. XM_013067441.2 → XP_012922895.1  regulator of G-protein signaling 6 isoform X3

    Conserved Domains (3) summary
    smart00224
    Location:258 → 319
    GGL; G protein gamma subunit-like motifs
    cd04450
    Location:31 → 119
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    cl02565
    Location:321 → 410
    RGS; Regulator of G protein signaling (RGS) domain superfamily

  3. XM_004837268.3 → XP_004837325.1  regulator of G-protein signaling 6 isoform X1

    See identical proteins and their annotated locations for XP_004837325.1

    Conserved Domains (3) summary
    smart00224
    Location:258 → 319
    GGL; G protein gamma subunit-like motifs
    cd08737
    Location:328 → 452
    RGS_RGS6; Regulator of G protein signaling (RGS) domain found in the RGS6 protein
    cd04450
    Location:31 → 119
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...

  4. XM_004837273.3 → XP_004837330.1  regulator of G-protein signaling 6 isoform X4

    UniProtKB/TrEMBL
    A0A0P6JH52, G5BJM1
    Related
    ENSHGLP00000016826.1, ENSHGLT00000016997.1
    Conserved Domains (3) summary
    smart00224
    Location:258 → 319
    GGL; G protein gamma subunit-like motifs
    cd08737
    Location:328 → 452
    RGS_RGS6; Regulator of G protein signaling (RGS) domain found in the RGS6 protein
    cd04450
    Location:31 → 119
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...

  5. XM_004837274.3 → XP_004837331.1  regulator of G-protein signaling 6 isoform X5

    UniProtKB/TrEMBL
    G5BJM1
    Related
    ENSHGLP00000016825.1, ENSHGLT00000016996.1
    Conserved Domains (3) summary
    smart00224
    Location:258 → 319
    GGL; G protein gamma subunit-like motifs
    cd08737
    Location:328 → 452
    RGS_RGS6; Regulator of G protein signaling (RGS) domain found in the RGS6 protein
    cd04450
    Location:31 → 119
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...

  6. XM_004837269.3 → XP_004837326.1  regulator of G-protein signaling 6 isoform X1

    See identical proteins and their annotated locations for XP_004837326.1

    Conserved Domains (3) summary
    smart00224
    Location:258 → 319
    GGL; G protein gamma subunit-like motifs
    cd08737
    Location:328 → 452
    RGS_RGS6; Regulator of G protein signaling (RGS) domain found in the RGS6 protein
    cd04450
    Location:31 → 119
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...

  7. XM_004837271.3 → XP_004837328.1  regulator of G-protein signaling 6 isoform X2

    Conserved Domains (3) summary
    smart00224
    Location:258 → 319
    GGL; G protein gamma subunit-like motifs
    cd08737
    Location:328 → 452
    RGS_RGS6; Regulator of G protein signaling (RGS) domain found in the RGS6 protein
    cd04450
    Location:31 → 119
    DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
Nucleotide Protein
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