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Six4 SIX homeobox 4 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101719647, updated on 8-Mar-2024

Summary

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Gene symbol
Six4
Gene description
SIX homeobox 4
See related
Ensembl:ENSHGLG00000013136
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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See Six4 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
4
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624734.1 (40397276..40409951)

NW_004624734.1Genomic Context describing neighboring genes Neighboring gene MNAT1 component of CDK activating kinase Neighboring gene fanconi-associated nuclease 1 pseudogene Neighboring gene uncharacterized LOC110346591 Neighboring gene KRAB domain-containing protein 4 pseudogene Neighboring gene SIX homeobox 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624734 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
homeobox protein SIX4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624734.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    40397276..40409951
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013067795.2 → XP_012923249.1  homeobox protein SIX4 isoform X2

    UniProtKB/TrEMBL
    G5C5H9
    Conserved Domains (2) summary
    cd00086
    Location:207 → 261
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam16878
    Location:87 → 196
    SIX1_SD; Transcriptional regulator, SIX1, N-terminal SD domain

  2. XM_004837442.2 → XP_004837499.1  homeobox protein SIX4 isoform X1

    UniProtKB/TrEMBL
    G5C5H9
    Related
    ENSHGLP00000018330.1, ENSHGLT00000018514.1
    Conserved Domains (2) summary
    cd00086
    Location:215 → 269
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam16878
    Location:95 → 204
    SIX1_SD; Transcriptional regulator, SIX1, N-terminal SD domain

  3. XM_021247900.1 → XP_021103559.1  homeobox protein SIX4 isoform X3

    Conserved Domains (2) summary
    cd00086
    Location:215 → 269
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam16878
    Location:95 → 204
    SIX1_SD; Transcriptional regulator, SIX1, N-terminal SD domain
Nucleotide Protein
Heading Accession and Version

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