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Lgr5 leucine rich repeat containing G protein-coupled receptor 5 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101717513, updated on 8-Mar-2024

Summary

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Gene symbol
Lgr5
Gene description
leucine rich repeat containing G protein-coupled receptor 5
See related
Ensembl:ENSHGLG00000004903
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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See Lgr5 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
19
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624750.1 (26185196..26302717, complement)

NW_004624750.1Genomic Context describing neighboring genes Neighboring gene zinc finger C3H1-type containing Neighboring gene mitochondrial fission regulator 2 pseudogene Neighboring gene uncharacterized LOC110349228 Neighboring gene protein phosphatase 1 regulatory subunit 42-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624750 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein-hormone receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
leucine-rich repeat-containing G-protein coupled receptor 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624750.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    26185196..26302717 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013072244.2 → XP_012927698.2  leucine-rich repeat-containing G-protein coupled receptor 5 isoform X1

    Related
    ENSHGLP00000006709.1, ENSHGLT00000006792.1
    Conserved Domains (5) summary
    sd00031
    Location:291 → 312
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:9 → 28
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:312 → 391
    LRR_8; Leucine rich repeat
    cd15363
    Location:495 → 768
    7tmA_LGR5; leucine-rich repeats-containing G protein-coupled receptor 5, member of the class A family of seven-transmembrane G protein-coupled receptors
    cl26793
    Location:9 → 348
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional

  2. XM_021258527.1 → XP_021114186.1  leucine-rich repeat-containing G-protein coupled receptor 5 isoform X2

    Conserved Domains (5) summary
    sd00031
    Location:280 → 301
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:18 → 41
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:301 → 380
    LRR_8; Leucine rich repeat
    cd15363
    Location:484 → 757
    7tmA_LGR5; leucine-rich repeats-containing G protein-coupled receptor 5, member of the class A family of seven-transmembrane G protein-coupled receptors
    cl26793
    Location:14 → 337
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
Nucleotide Protein
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