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Socs2 suppressor of cytokine signaling 2 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101716580, updated on 8-Mar-2024

Summary

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Gene symbol
Socs2
Gene description
suppressor of cytokine signaling 2
See related
Ensembl:ENSHGLG00000006324
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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See Socs2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
8
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624750.1 (13333393..13339018, complement)

NW_004624750.1Genomic Context describing neighboring genes Neighboring gene CASP2 and RIPK1 domain containing adaptor with death domain Neighboring gene uncharacterized LOC110349131 Neighboring gene citrate synthase, mitochondrial pseudogene Neighboring gene uncharacterized LOC110349201

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624750 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
suppressor of cytokine signaling 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624750.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    13333393..13339018 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021258470.1 → XP_021114129.1  suppressor of cytokine signaling 2

    UniProtKB/TrEMBL
    A0A0P6K7G7
    Conserved Domains (2) summary
    cd10383
    Location:40 → 142
    SH2_SOCS2; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03736
    Location:158 → 198
    SOCS_SOCS2; SOCS (suppressors of cytokine signaling) box of SOCS2-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS2 has recently been shown to regulate ...

  2. XM_021258471.1 → XP_021114130.1  suppressor of cytokine signaling 2

    UniProtKB/TrEMBL
    A0A0P6K7G7
    Conserved Domains (2) summary
    cd10383
    Location:40 → 142
    SH2_SOCS2; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03736
    Location:158 → 198
    SOCS_SOCS2; SOCS (suppressors of cytokine signaling) box of SOCS2-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS2 has recently been shown to regulate ...

  3. XM_004844963.3 → XP_004845020.1  suppressor of cytokine signaling 2

    See identical proteins and their annotated locations for XP_004845020.1

    UniProtKB/TrEMBL
    A0A0P6K7G7
    Conserved Domains (2) summary
    cd10383
    Location:40 → 142
    SH2_SOCS2; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03736
    Location:158 → 198
    SOCS_SOCS2; SOCS (suppressors of cytokine signaling) box of SOCS2-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS2 has recently been shown to regulate ...

  4. XM_021258468.1 → XP_021114127.1  suppressor of cytokine signaling 2

    UniProtKB/TrEMBL
    A0A0P6K7G7
    Related
    ENSHGLP00000008786.1, ENSHGLT00000008881.1
    Conserved Domains (2) summary
    cd10383
    Location:40 → 142
    SH2_SOCS2; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03736
    Location:158 → 198
    SOCS_SOCS2; SOCS (suppressors of cytokine signaling) box of SOCS2-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS2 has recently been shown to regulate ...

  5. XM_004844962.3 → XP_004845019.1  suppressor of cytokine signaling 2

    See identical proteins and their annotated locations for XP_004845019.1

    UniProtKB/TrEMBL
    A0A0P6K7G7
    Conserved Domains (2) summary
    cd10383
    Location:40 → 142
    SH2_SOCS2; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03736
    Location:158 → 198
    SOCS_SOCS2; SOCS (suppressors of cytokine signaling) box of SOCS2-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS2 has recently been shown to regulate ...

  6. XM_004844961.3 → XP_004845018.1  suppressor of cytokine signaling 2

    See identical proteins and their annotated locations for XP_004845018.1

    UniProtKB/TrEMBL
    A0A0P6K7G7
    Conserved Domains (2) summary
    cd10383
    Location:40 → 142
    SH2_SOCS2; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03736
    Location:158 → 198
    SOCS_SOCS2; SOCS (suppressors of cytokine signaling) box of SOCS2-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS2 has recently been shown to regulate ...
Nucleotide Protein
Heading Accession and Version

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