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Sox8 SRY-box transcription factor 8 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101711198, updated on 8-Mar-2024

Summary

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Gene symbol
Sox8
Gene description
SRY-box transcription factor 8
See related
Ensembl:ENSHGLG00000002777
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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See Sox8 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
3
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624913.1 (1759460..1764242)

NW_004624913.1Genomic Context describing neighboring genes Neighboring gene ferritin light chain pseudogene Neighboring gene lipase maturation factor 1 Neighboring gene eukaryotic translation initiation factor 4E pseudogene Neighboring gene very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 pseudogene Neighboring gene uncharacterized LOC110347317 Neighboring gene somatostatin receptor 5

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624913 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in enteric nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in morphogenesis of an epithelium IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neural crest cell development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peripheral nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transcription factor SOX-8
Names
SRY-box 8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624913.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    1759460..1764242
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004873842.3 → XP_004873899.1  transcription factor SOX-8

    Related
    ENSHGLP00000003773.1, ENSHGLT00000003829.1
    Conserved Domains (2) summary
    cd01388
    Location:101 → 171
    SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
    pfam12444
    Location:18 → 89
    Sox_N; Sox developmental protein N terminal
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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