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Fgd6 FYVE, RhoGEF and PH domain containing 6 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101708057, updated on 8-Mar-2024

Summary

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Gene symbol
Fgd6
Gene description
FYVE, RhoGEF and PH domain containing 6
See related
Ensembl:ENSHGLG00000010509
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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See Fgd6 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
23
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624750.1 (11869178..11966668)

NW_004624750.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101706222 Neighboring gene vezatin, adherens junctions transmembrane protein Neighboring gene uncharacterized LOC110349195 Neighboring gene nuclear receptor subfamily 2 group C member 1 Neighboring gene NADH:ubiquinone oxidoreductase subunit A12

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624750 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
FYVE, RhoGEF and PH domain-containing protein 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624750.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    11869178..11966668
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021258458.1 → XP_021114117.1  FYVE, RhoGEF and PH domain-containing protein 6 isoform X3

    Conserved Domains (5) summary
    PHA03169
    Location:558 → 729
    PHA03169; hypothetical protein; Provisional
    cd13237
    Location:1196 → 1284
    PH2_FGD5_FGD6; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia proteins 5 and 6 pleckstrin homology (PH) domain, C-terminus
    cd15743
    Location:1079 → 1139
    FYVE_FGD6; FYVE domain found in FYVE, RhoGEF and PH domain-containing protein 6 (FGD6) and similar proteins
    pfam00621
    Location:737 → 920
    RhoGEF; RhoGEF domain
    cl17171
    Location:939 → 1061
    PH-like; Pleckstrin homology-like domain

  2. XM_004844931.3 → XP_004844988.1  FYVE, RhoGEF and PH domain-containing protein 6 isoform X1

    Conserved Domains (5) summary
    cd13237
    Location:1333 → 1421
    PH2_FGD5_FGD6; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia proteins 5 and 6 pleckstrin homology (PH) domain, C-terminus
    cd15743
    Location:1216 → 1276
    FYVE_FGD6; FYVE domain found in FYVE, RhoGEF and PH domain-containing protein 6 (FGD6) and similar proteins
    pfam00169
    Location:1333 → 1423
    PH; PH domain
    pfam00621
    Location:874 → 1058
    RhoGEF; RhoGEF domain
    cl17171
    Location:1076 → 1198
    PH-like; Pleckstrin homology-like domain

  3. XM_004844932.3 → XP_004844989.1  FYVE, RhoGEF and PH domain-containing protein 6 isoform X2

    Related
    ENSHGLP00000014679.1, ENSHGLT00000014824.1
    Conserved Domains (5) summary
    cd13237
    Location:1332 → 1420
    PH2_FGD5_FGD6; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia proteins 5 and 6 pleckstrin homology (PH) domain, C-terminus
    cd15743
    Location:1215 → 1275
    FYVE_FGD6; FYVE domain found in FYVE, RhoGEF and PH domain-containing protein 6 (FGD6) and similar proteins
    pfam00169
    Location:1332 → 1422
    PH; PH domain
    pfam00621
    Location:873 → 1057
    RhoGEF; RhoGEF domain
    cl17171
    Location:1075 → 1197
    PH-like; Pleckstrin homology-like domain

  4. XM_013072289.2 → XP_012927743.1  FYVE, RhoGEF and PH domain-containing protein 6 isoform X4

    Conserved Domains (6) summary
    cd13237
    Location:467 → 555
    PH2_FGD5_FGD6; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia proteins 5 and 6 pleckstrin homology (PH) domain, C-terminus
    cd15743
    Location:350 → 410
    FYVE_FGD6; FYVE domain found in FYVE, RhoGEF and PH domain-containing protein 6 (FGD6) and similar proteins
    pfam00169
    Location:467 → 557
    PH; PH domain
    pfam00621
    Location:8 → 192
    RhoGEF; RhoGEF domain
    pfam01254
    Location:375 → 450
    TP2; Nuclear transition protein 2
    cl17171
    Location:210 → 332
    PH-like; Pleckstrin homology-like domain

RNA

  1. XR_002395008.1 RNA Sequence

  2. XR_002395009.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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