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Atp2b2 ATPase plasma membrane Ca2+ transporting 2 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101707619, updated on 8-Mar-2024

Summary

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Gene symbol
Atp2b2
Gene description
ATPase plasma membrane Ca2+ transporting 2
Locus tag
GW7_19471
See related
Ensembl:ENSHGLG00000007041
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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See Atp2b2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
26
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624731.1 (4836109..5190990)

NW_004624731.1Genomic Context describing neighboring genes Neighboring gene FANCD2 opposite strand Neighboring gene BRICK1 subunit of SCAR/WAVE actin nucleating complex Neighboring gene 40S ribosomal protein S15 pseudogene Neighboring gene protein PROCA1-like Neighboring gene wee1-like protein kinase 2 Neighboring gene uncharacterized LOC106009859 Neighboring gene SEC13 homolog, nuclear pore and COPII coat complex component Neighboring gene ghrelin and obestatin prepropeptide

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624731 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables P-type calcium transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables PDZ domain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cytosolic calcium ion concentration IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic density membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
plasma membrane calcium-transporting ATPase 2
Names
Plasma membrane calcium-transporting ATPase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624731.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    4836109..5190990
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004835329.3 → XP_004835386.1  plasma membrane calcium-transporting ATPase 2 isoform X1

    See identical proteins and their annotated locations for XP_004835386.1

    UniProtKB/TrEMBL
    G5BX71
    Conserved Domains (7) summary
    TIGR01517
    Location:12 → 1087
    ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
    pfam00122
    Location:161 → 488
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:903 → 1081
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:51 → 113
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam12424
    Location:1126 → 1173
    ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
    pfam12710
    Location:690 → 829
    HAD; haloacid dehalogenase-like hydrolase
    pfam13246
    Location:549 → 638
    Cation_ATPase; Cation transport ATPase (P-type)

  2. XM_004835328.2 → XP_004835385.1  plasma membrane calcium-transporting ATPase 2 isoform X1

    See identical proteins and their annotated locations for XP_004835385.1

    UniProtKB/TrEMBL
    G5BX71
    Related
    ENSHGLP00000009808.1, ENSHGLT00000009916.1
    Conserved Domains (7) summary
    TIGR01517
    Location:12 → 1087
    ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
    pfam00122
    Location:161 → 488
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:903 → 1081
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:51 → 113
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam12424
    Location:1126 → 1173
    ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
    pfam12710
    Location:690 → 829
    HAD; haloacid dehalogenase-like hydrolase
    pfam13246
    Location:549 → 638
    Cation_ATPase; Cation transport ATPase (P-type)

  3. XM_004835330.2 → XP_004835387.1  plasma membrane calcium-transporting ATPase 2 isoform X2

    Conserved Domains (7) summary
    TIGR01517
    Location:12 → 1086
    ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
    pfam00122
    Location:161 → 487
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:902 → 1080
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:51 → 113
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam12424
    Location:1125 → 1172
    ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
    pfam12710
    Location:689 → 828
    HAD; haloacid dehalogenase-like hydrolase
    pfam13246
    Location:548 → 637
    Cation_ATPase; Cation transport ATPase (P-type)

  4. XM_004835331.2 → XP_004835388.1  plasma membrane calcium-transporting ATPase 2 isoform X3

    Conserved Domains (7) summary
    TIGR01517
    Location:12 → 1056
    ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
    pfam00122
    Location:161 → 457
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:872 → 1050
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:51 → 113
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam12424
    Location:1095 → 1142
    ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
    pfam12710
    Location:659 → 798
    HAD; haloacid dehalogenase-like hydrolase
    pfam13246
    Location:518 → 607
    Cation_ATPase; Cation transport ATPase (P-type)

  5. XM_004835335.3 → XP_004835392.1  plasma membrane calcium-transporting ATPase 2 isoform X6

    Related
    ENSHGLP00000009810.1, ENSHGLT00000009918.1
    Conserved Domains (7) summary
    TIGR01517
    Location:12 → 1042
    ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
    pfam00122
    Location:161 → 443
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:858 → 1036
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:51 → 113
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam12424
    Location:1081 → 1128
    ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
    pfam12710
    Location:645 → 784
    HAD; haloacid dehalogenase-like hydrolase
    pfam13246
    Location:504 → 593
    Cation_ATPase; Cation transport ATPase (P-type)

  6. XM_004835332.3 → XP_004835389.1  plasma membrane calcium-transporting ATPase 2 isoform X4

    Conserved Domains (7) summary
    TIGR01517
    Location:12 → 1087
    ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
    pfam00122
    Location:161 → 488
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:903 → 1081
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:51 → 113
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam12424
    Location:1126 → 1190
    ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
    pfam12710
    Location:690 → 829
    HAD; haloacid dehalogenase-like hydrolase
    pfam13246
    Location:549 → 638
    Cation_ATPase; Cation transport ATPase (P-type)

  7. XM_004835336.3 → XP_004835393.1  plasma membrane calcium-transporting ATPase 2 isoform X7

    Conserved Domains (7) summary
    TIGR01517
    Location:12 → 1056
    ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
    pfam00122
    Location:161 → 457
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:872 → 1050
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:51 → 113
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam12424
    Location:1095 → 1159
    ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
    pfam12710
    Location:659 → 798
    HAD; haloacid dehalogenase-like hydrolase
    pfam13246
    Location:518 → 607
    Cation_ATPase; Cation transport ATPase (P-type)

  8. XM_021260578.1 → XP_021116237.1  plasma membrane calcium-transporting ATPase 2 isoform X8

    Conserved Domains (2) summary
    pfam12424
    Location:1081 → 1121
    ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
    cl27747
    Location:12 → 1042
    E1-E2_ATPase; E1-E2 ATPase

  9. XM_004835334.2 → XP_004835391.1  plasma membrane calcium-transporting ATPase 2 isoform X5

    Related
    ENSHGLP00000009809.1, ENSHGLT00000009917.1
    Conserved Domains (7) summary
    TIGR01517
    Location:12 → 1087
    ATPase-IIB_Ca; plasma-membrane calcium-translocating P-type ATPase
    pfam00122
    Location:161 → 488
    E1-E2_ATPase; E1-E2 ATPase
    pfam00689
    Location:903 → 1081
    Cation_ATPase_C; Cation transporting ATPase, C-terminus
    pfam00690
    Location:51 → 113
    Cation_ATPase_N; Cation transporter/ATPase, N-terminus
    pfam12424
    Location:1126 → 1190
    ATP_Ca_trans_C; Plasma membrane calcium transporter ATPase C terminal
    pfam12710
    Location:690 → 829
    HAD; haloacid dehalogenase-like hydrolase
    pfam13246
    Location:549 → 638
    Cation_ATPase; Cation transport ATPase (P-type)
Nucleotide Protein
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