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Apaf1 apoptotic peptidase activating factor 1 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101706721, updated on 8-Mar-2024

Summary

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Gene symbol
Apaf1
Gene description
apoptotic peptidase activating factor 1
See related
Ensembl:ENSHGLG00000007198
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
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Genomic context

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See Apaf1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
23
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624750.1 (8835521..8940957, complement)

NW_004624750.1Genomic Context describing neighboring genes Neighboring gene ankyrin repeat and sterile alpha motif domain containing 1B Neighboring gene uncharacterized LOC110349188 Neighboring gene uncharacterized LOC101718089 Neighboring gene histone acetyltransferase KAT5-like Neighboring gene solute carrier family 25 member 3 Neighboring gene IKBKB interacting protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624750 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ADP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in apoptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of apoptosome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
apoptotic protease-activating factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624750.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    8835521..8940957 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021258426.1 → XP_021114085.1  apoptotic protease-activating factor 1

    UniProtKB/TrEMBL
    A0A0P6J204
    Related
    ENSHGLP00000010023.1, ENSHGLT00000010134.1
    Conserved Domains (4) summary
    cd00200
    Location:607 → 910
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cd08323
    Location:7 → 92
    CARD_APAF1; Caspase activation and recruitment domain similar to that found in Apoptotic Protease-Activating Factor 1
    sd00039
    Location:623 → 655
    7WD40; WD40 repeat [structural motif]
    pfam00931
    Location:129 → 414
    NB-ARC; NB-ARC domain
Nucleotide Protein
Heading Accession and Version

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