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Asxl1 ASXL transcriptional regulator 1 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101705975, updated on 8-Mar-2024

Summary

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Gene symbol
Asxl1
Gene description
ASXL transcriptional regulator 1
See related
Ensembl:ENSHGLG00000017426
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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See Asxl1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
14
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624741.1 (188985..258065, complement)

NW_004624741.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110348309 Neighboring gene nucleolar protein 4 like Neighboring gene uncharacterized LOC101705727 Neighboring gene kinesin family member 3B Neighboring gene G patch domain-containing protein 11-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624741 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables peroxisome proliferator activated receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in animal organ morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of PR-DUB complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
putative Polycomb group protein ASXL1
Names
additional sex combs like 1, transcriptional regulator

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624741.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    188985..258065 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004840576.3 → XP_004840633.1  putative Polycomb group protein ASXL1 isoform X1

    UniProtKB/TrEMBL
    A0A0P6JEU0
    Conserved Domains (3) summary
    pfam05066
    Location:11 → 83
    HARE-HTH; HB1, ASXL, restriction endonuclease HTH domain
    pfam13919
    Location:236 → 359
    ASXH; Asx homology domain
    pfam13922
    Location:1498 → 1531
    PHD_3; PHD domain of transcriptional enhancer, Asx

  2. XM_004840577.3 → XP_004840634.1  putative Polycomb group protein ASXL1 isoform X2

    Conserved Domains (3) summary
    pfam05066
    Location:11 → 82
    HARE-HTH; HB1, ASXL, restriction endonuclease HTH domain
    pfam13919
    Location:235 → 358
    ASXH; Asx homology domain
    pfam13922
    Location:1497 → 1530
    PHD_3; PHD domain of transcriptional enhancer, Asx

  3. XM_021254887.1 → XP_021110546.1  putative Polycomb group protein ASXL1 isoform X4

    Related
    ENSHGLP00000024445.1, ENSHGLT00000024666.1
    Conserved Domains (3) summary
    pfam05066
    Location:1 → 54
    HARE-HTH; HB1, ASXL, restriction endonuclease HTH domain
    pfam13919
    Location:207 → 330
    ASXH; Asx homology domain
    pfam13922
    Location:1469 → 1502
    PHD_3; PHD domain of transcriptional enhancer, Asx

  4. XM_004840578.3 → XP_004840635.1  putative Polycomb group protein ASXL1 isoform X3

    Conserved Domains (3) summary
    pfam05066
    Location:1 → 55
    HARE-HTH; HB1, ASXL, restriction endonuclease HTH domain
    pfam13919
    Location:208 → 331
    ASXH; Asx homology domain
    pfam13922
    Location:1470 → 1503
    PHD_3; PHD domain of transcriptional enhancer, Asx
Nucleotide Protein
Heading Accession and Version

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