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Syt1 synaptotagmin 1 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101701697, updated on 8-Mar-2024

Summary

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Gene symbol
Syt1
Gene description
synaptotagmin 1
Locus tag
GW7_11734
See related
Ensembl:ENSHGLG00000009038
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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See Syt1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624750.1 (18774670..19313932, complement)

NW_004624750.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110349217 Neighboring gene uncharacterized protein C1orf146 pseudogene Neighboring gene pro-apoptotic WT1 regulator Neighboring gene 60S ribosomal protein L38 pseudogene Neighboring gene uncharacterized LOC110349138 Neighboring gene uncharacterized LOC110349219

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624750 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent phospholipid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables clathrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylserine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables syntaxin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in calcium ion-regulated exocytosis of neurotransmitter IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to calcium ion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of calcium ion-dependent exocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of dopamine secretion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in synaptic vesicle endocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dense core granule IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synaptic vesicle membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
synaptotagmin-1
Names
Synaptotagmin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624750.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    18774670..19313932 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004844999.3 → XP_004845056.1  synaptotagmin-1 isoform X2

    See identical proteins and their annotated locations for XP_004845056.1

    UniProtKB/TrEMBL
    A0A0P6JFG6
    Conserved Domains (3) summary
    cd08385
    Location:140 → 262
    C2A_Synaptotagmin-1-5-6-9-10; C2A domain first repeat present in Synaptotagmins 1, 5, 6, 9, and 10
    cd08402
    Location:271 → 406
    C2B_Synaptotagmin-1; C2 domain second repeat present in Synaptotagmin 1
    cd21963
    Location:6 → 113
    Syt1_N; N-terminal domain of synaptotagmin-1 (Syt1) and similar proteins

  2. XM_004844995.3 → XP_004845052.1  synaptotagmin-1 isoform X1

    See identical proteins and their annotated locations for XP_004845052.1

    UniProtKB/TrEMBL
    G5C9J0
    Conserved Domains (3) summary
    cd08385
    Location:143 → 265
    C2A_Synaptotagmin-1-5-6-9-10; C2A domain first repeat present in Synaptotagmins 1, 5, 6, 9, and 10
    cd08402
    Location:274 → 409
    C2B_Synaptotagmin-1; C2 domain second repeat present in Synaptotagmin 1
    cd21963
    Location:6 → 113
    Syt1_N; N-terminal domain of synaptotagmin-1 (Syt1) and similar proteins

  3. XM_021258498.1 → XP_021114157.1  synaptotagmin-1 isoform X1

    UniProtKB/TrEMBL
    G5C9J0
    Related
    ENSHGLP00000012644.1, ENSHGLT00000012781.1
    Conserved Domains (3) summary
    cd08385
    Location:143 → 265
    C2A_Synaptotagmin-1-5-6-9-10; C2A domain first repeat present in Synaptotagmins 1, 5, 6, 9, and 10
    cd08402
    Location:274 → 409
    C2B_Synaptotagmin-1; C2 domain second repeat present in Synaptotagmin 1
    cd21963
    Location:6 → 113
    Syt1_N; N-terminal domain of synaptotagmin-1 (Syt1) and similar proteins
Nucleotide Protein
Heading Accession and Version

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