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L2HGDH L-2-hydroxyglutarate dehydrogenase [ Felis catus (domestic cat) ]

Gene ID: 101094353, updated on 17-Aug-2024

Summary

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Official Symbol
L2HGDH
Official Full Name
L-2-hydroxyglutarate dehydrogenase
Primary source
VGNC:VGNC:63181
See related
EnsemblRapid:ENSFCTG00005005645
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
human mouse all
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Genomic context

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See L2HGDH in Genome Data Viewer
Location:
chromosome: B3
Exon count:
12
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) B3 NC_058373.1 (97842945..97886153, complement)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) B3 NC_018728.3 (100205236..100248136, complement)

Chromosome B3 - NC_058373.1Genomic Context describing neighboring genes Neighboring gene valosin containing protein lysine methyltransferase Neighboring gene SOS Ras/Rho guanine nucleotide exchange factor 2 Neighboring gene distal membrane arm assembly component 2 like Neighboring gene cyclin dependent kinase like 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables (S)-2-hydroxy-acid oxidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 2-hydroxyglutarate dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
L-2-hydroxyglutarate dehydrogenase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058373.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    97842945..97886153 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023255679.2 → XP_023111447.2  L-2-hydroxyglutarate dehydrogenase, mitochondrial isoform X3

    Conserved Domains (1) summary
    PRK11728
    Location:61 → 413
    PRK11728; L-2-hydroxyglutarate oxidase

  2. XM_023255680.2 → XP_023111448.2  L-2-hydroxyglutarate dehydrogenase, mitochondrial isoform X5

    Conserved Domains (1) summary
    PRK11728
    Location:61 → 391
    PRK11728; L-2-hydroxyglutarate oxidase

  3. XM_045059894.1 → XP_044915829.1  L-2-hydroxyglutarate dehydrogenase, mitochondrial isoform X4

    Conserved Domains (1) summary
    PRK11728
    Location:61 → 413
    PRK11728; L-2-hydroxyglutarate oxidase

  4. XM_023255678.2 → XP_023111446.2  L-2-hydroxyglutarate dehydrogenase, mitochondrial isoform X1

    Related
    ENSFCTP00005010691.1, ENSFCTT00005015744.1
    Conserved Domains (1) summary
    PRK11728
    Location:61 → 457
    PRK11728; L-2-hydroxyglutarate oxidase

  5. XM_045059893.1 → XP_044915828.1  L-2-hydroxyglutarate dehydrogenase, mitochondrial isoform X2

    Related
    ENSFCTP00005010677.1, ENSFCTT00005015726.1
    Conserved Domains (1) summary
    PRK11728
    Location:35 → 431
    PRK11728; L-2-hydroxyglutarate oxidase
Nucleotide Protein
Heading Accession and Version

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