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SOAT1 sterol O-acyltransferase 1 [ Felis catus (domestic cat) ]

Gene ID: 101081271, updated on 8-Mar-2024

Summary

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Official Symbol
SOAT1
Official Full Name
sterol O-acyltransferase 1
Primary source
VGNC:VGNC:65561
See related
EnsemblRapid:ENSFCTG00005004267
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
human mouse all
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Genomic context

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See SOAT1 in Genome Data Viewer
Location:
chromosome: F1
Exon count:
17
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) F1 NC_058384.1 (20834296..20917184)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) F1 NC_018739.3 (22999509..23082672)

Chromosome F1 - NC_058384.1Genomic Context describing neighboring genes Neighboring gene ABL proto-oncogene 2, non-receptor tyrosine kinase Neighboring gene uncharacterized LOC123382793 Neighboring gene uncharacterized LOC109495605 Neighboring gene U6 spliceosomal RNA Neighboring gene U6 spliceosomal RNA Neighboring gene inosine triphosphate pyrophosphatase-like Neighboring gene axonemal dynein light chain domain containing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. SOAT1 missense variant in two cats with sebaceous gland dysplasia. Kiener S, et al. Mol Genet Genomics, 2023 Jul. PMID 37060467, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. SOAT1 missense variant in two cats with sebaceous gland dysplasia.
    Title: SOAT1 missense variant in two cats with sebaceous gland dysplasia.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cholesterol O-acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cholesterol binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fatty-acyl-CoA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cholesterol efflux IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cholesterol homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cholesterol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sterol O-acyltransferase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058384.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    20834296..20917184
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011291018.4 → XP_011289320.1  sterol O-acyltransferase 1 isoform X1

    See identical proteins and their annotated locations for XP_011289320.1

    UniProtKB/TrEMBL
    A0A5F5XKF1, M3W8J8
    Related
    ENSFCTP00005007135.1, ENSFCTT00005011479.1
    Conserved Domains (1) summary
    pfam03062
    Location:170 → 519
    MBOAT; MBOAT, membrane-bound O-acyltransferase family

  2. XM_011291017.4 → XP_011289319.1  sterol O-acyltransferase 1 isoform X1

    See identical proteins and their annotated locations for XP_011289319.1

    UniProtKB/TrEMBL
    A0A5F5XKF1, M3W8J8
    Related
    ENSFCTP00005007143.1, ENSFCTT00005011487.1
    Conserved Domains (1) summary
    pfam03062
    Location:170 → 519
    MBOAT; MBOAT, membrane-bound O-acyltransferase family

  3. XM_045048478.1 → XP_044904413.1  sterol O-acyltransferase 1 isoform X2

    UniProtKB/TrEMBL
    A0A337SH03
    Related
    ENSFCTP00005007126.1, ENSFCTT00005011470.1
    Conserved Domains (1) summary
    pfam03062
    Location:123 → 472
    MBOAT; membrane-bound O-acyltransferase family
Nucleotide Protein
Heading Accession and Version

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