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GPR35 G protein-coupled receptor 35 [ Canis lupus familiaris (dog) ]

Gene ID: 100855802, updated on 17-Aug-2024

Summary

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Official Symbol
GPR35provided by VGNC
Official Full Name
G protein-coupled receptor 35provided by VGNC
Primary source
VGNC:VGNC:110509
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See GPR35 in Genome Data Viewer
Location:
chromosome: 25
Exon count:
5
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 25 NC_051829.1 (51017995..51032727)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 25 NC_006607.4 (51036038..51050997)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 25 NC_049246.1 (50882551..50897299)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 25 NC_049285.1 (50859957..50874922)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 25 NC_049766.1 (50605715..50620874)

Chromosome 25 - NC_051829.1Genomic Context describing neighboring genes Neighboring gene ankyrin repeat and MYND domain containing 1 Neighboring gene arginyl aminopeptidase like 1 Neighboring gene calpain 10 Neighboring gene aquaporin 12 Neighboring gene kinesin family member 1A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Hydrophobicity, rather than secondary structure, is essential for the SRP dependent targeting of GPR35 to the ER membrane. Cherry JK, et al. J Bioenerg Biomembr, 2019 Apr. PMID 30706279, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Hydrophobicity, rather than secondary structure, is essential for the SRP dependent targeting of GPR35 to the ER membrane.
    Title: Hydrophobicity, rather than secondary structure, is essential for the SRP dependent targeting of GPR35 to the ER membrane.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phospholipase C-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of Rho protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
G-protein coupled receptor 35

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051829.1 Reference ROS_Cfam_1.0

    Range
    51017995..51032727
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038435992.1 → XP_038291920.1  G-protein coupled receptor 35 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LKV1, A0A8C0Z4T0
    Conserved Domains (2) summary
    cd14964
    Location:51 → 76
    7tm_GPCRs; TM helix 2 [structural motif]
    cl28897
    Location:39 → 280
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  2. XM_038435994.1 → XP_038291922.1  G-protein coupled receptor 35 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LKV1, A0A8C0Z4T0
    Conserved Domains (2) summary
    cd14964
    Location:51 → 76
    7tm_GPCRs; TM helix 2 [structural motif]
    cl28897
    Location:39 → 280
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  3. XM_038435991.1 → XP_038291919.1  G-protein coupled receptor 35 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LKV1, A0A8C0Z4T0
    Conserved Domains (2) summary
    cd14964
    Location:51 → 76
    7tm_GPCRs; TM helix 2 [structural motif]
    cl28897
    Location:39 → 280
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  4. XM_038435993.1 → XP_038291921.1  G-protein coupled receptor 35 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LKV1, A0A8C0Z4T0
    Conserved Domains (2) summary
    cd14964
    Location:51 → 76
    7tm_GPCRs; TM helix 2 [structural motif]
    cl28897
    Location:39 → 280
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049285.1 Alternate UMICH_Zoey_3.1

    Range
    50859957..50874922
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038510915.1 → XP_038366843.1  G-protein coupled receptor 35 isoform X1

    Conserved Domains (2) summary
    cd14964
    Location:51 → 76
    7tm_GPCRs; TM helix 2 [structural motif]
    cl28897
    Location:39 → 280
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  2. XM_038510917.1 → XP_038366845.1  G-protein coupled receptor 35 isoform X1

    Conserved Domains (2) summary
    cd14964
    Location:51 → 76
    7tm_GPCRs; TM helix 2 [structural motif]
    cl28897
    Location:39 → 280
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  3. XM_038510914.1 → XP_038366842.1  G-protein coupled receptor 35 isoform X1

    Conserved Domains (2) summary
    cd14964
    Location:51 → 76
    7tm_GPCRs; TM helix 2 [structural motif]
    cl28897
    Location:39 → 280
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  4. XM_038510916.1 → XP_038366844.1  G-protein coupled receptor 35 isoform X1

    Conserved Domains (2) summary
    cd14964
    Location:51 → 76
    7tm_GPCRs; TM helix 2 [structural motif]
    cl28897
    Location:39 → 280
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049766.1 Alternate UNSW_CanFamBas_1.0

    Range
    50605715..50620874
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038638641.1 → XP_038494569.1  G-protein coupled receptor 35 isoform X1

    Conserved Domains (2) summary
    cd14964
    Location:51 → 76
    7tm_GPCRs; TM helix 2 [structural motif]
    cl28897
    Location:39 → 280
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  2. XM_038638643.1 → XP_038494571.1  G-protein coupled receptor 35 isoform X1

    Conserved Domains (2) summary
    cd14964
    Location:51 → 76
    7tm_GPCRs; TM helix 2 [structural motif]
    cl28897
    Location:39 → 280
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  3. XM_038638640.1 → XP_038494568.1  G-protein coupled receptor 35 isoform X2

  4. XM_038638642.1 → XP_038494570.1  G-protein coupled receptor 35 isoform X1

    Conserved Domains (2) summary
    cd14964
    Location:51 → 76
    7tm_GPCRs; TM helix 2 [structural motif]
    cl28897
    Location:39 → 280
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049246.1 Alternate UU_Cfam_GSD_1.0

    Range
    50882551..50897299
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038574415.1 → XP_038430343.1  G-protein coupled receptor 35 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LKV1, A0A8C0Z4T0
    Conserved Domains (2) summary
    cd14964
    Location:51 → 76
    7tm_GPCRs; TM helix 2 [structural motif]
    cl28897
    Location:39 → 280
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  2. XM_038574417.1 → XP_038430345.1  G-protein coupled receptor 35 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LKV1, A0A8C0Z4T0
    Conserved Domains (2) summary
    cd14964
    Location:51 → 76
    7tm_GPCRs; TM helix 2 [structural motif]
    cl28897
    Location:39 → 280
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  3. XM_038574414.1 → XP_038430342.1  G-protein coupled receptor 35 isoform X3

    UniProtKB/TrEMBL
    A0A8C0NDK0

  4. XM_038574416.1 → XP_038430344.1  G-protein coupled receptor 35 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LKV1, A0A8C0Z4T0
    Conserved Domains (2) summary
    cd14964
    Location:51 → 76
    7tm_GPCRs; TM helix 2 [structural motif]
    cl28897
    Location:39 → 280
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006607.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    51036038..51050997
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022409756.2 → XP_022265464.2  G-protein coupled receptor 35 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LKV1, A0A8C0Z4T0
    Conserved Domains (2) summary
    cd14964
    Location:51 → 76
    7tm_GPCRs; TM helix 2 [structural motif]
    cl28897
    Location:39 → 280
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  2. XM_038458699.1 → XP_038314627.1  G-protein coupled receptor 35 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LKV1, A0A8C0Z4T0
    Conserved Domains (2) summary
    cd14964
    Location:51 → 76
    7tm_GPCRs; TM helix 2 [structural motif]
    cl28897
    Location:39 → 280
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  3. XM_005635955.4 → XP_005636012.3  G-protein coupled receptor 35 isoform X4

    UniProtKB/TrEMBL
    A0A8C0NDK0
    Conserved Domains (2) summary
    cd14964
    Location:282 → 307
    7tm_GPCRs; TM helix 2 [structural motif]
    cl28897
    Location:270 → 511
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

  4. XM_038458698.1 → XP_038314626.1  G-protein coupled receptor 35 isoform X1

    UniProtKB/TrEMBL
    A0A8C0LKV1, A0A8C0Z4T0
    Conserved Domains (2) summary
    cd14964
    Location:51 → 76
    7tm_GPCRs; TM helix 2 [structural motif]
    cl28897
    Location:39 → 280
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
Nucleotide Protein
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