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Fgfr1 fibroblast growth factor receptor 1 [ Cavia porcellus (domestic guinea pig) ]

Gene ID: 100731156, updated on 10-Oct-2024

Summary

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Gene symbol
Fgfr1
Gene description
fibroblast growth factor receptor 1
See related
Ensembl:ENSCPOG00000006553
Gene type
protein coding
RefSeq status
MODEL
Organism
Cavia porcellus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
Orthologs
human mouse all
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Genomic context

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See Fgfr1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947512.1 (45184267..45232529, complement)
103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176302.1 (1211473..1261366)

NW_026947512.1Genomic Context describing neighboring genes Neighboring gene DDHD domain containing 2 Neighboring gene phospholipid phosphatase 5 Neighboring gene nuclear receptor binding SET domain protein 3 Neighboring gene leucine zipper and EF-hand containing transmembrane protein 2 Neighboring gene uncharacterized LOC134473979 Neighboring gene uncharacterized LOC134473879

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fibroblast growth factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fibroblast growth factor receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fibroblast growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fibroblast growth factor receptor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCavPor4.1

Genomic

  1. NW_026947512.1 Reference mCavPor4.1

    Range
    45184267..45232529 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063239830.1 → XP_063095900.1  fibroblast growth factor receptor 1 isoform X3

  2. XM_063239829.1 → XP_063095899.1  fibroblast growth factor receptor 1 isoform X1

    UniProtKB/TrEMBL
    H0V817

  3. XM_063239827.1 → XP_063095897.1  fibroblast growth factor receptor 1 isoform X1

    UniProtKB/TrEMBL
    H0V817

  4. XM_023561981.2 → XP_023417749.1  fibroblast growth factor receptor 1 isoform X4

    UniProtKB/TrEMBL
    A0A286XMS2
    Conserved Domains (4) summary
    cd04973
    Location:40 → 118
    Ig1_FGFR; First immunoglobulin (Ig)-like domain of fibroblast growth factor receptor (FGFR)
    cd05857
    Location:161 → 245
    Ig2_FGFR; Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor
    cd05858
    Location:268 → 357
    Ig3_FGFR-2; Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor 2 (FGFR2)
    cd05098
    Location:460 → 761
    PTKc_FGFR1; Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 1

  5. XM_023561980.2 → XP_023417748.1  fibroblast growth factor receptor 1 isoform X2

    UniProtKB/TrEMBL
    A0A286XMS2
    Conserved Domains (4) summary
    cd04973
    Location:40 → 118
    Ig1_FGFR; First immunoglobulin (Ig)-like domain of fibroblast growth factor receptor (FGFR)
    cd05857
    Location:163 → 247
    Ig2_FGFR; Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor
    cd05858
    Location:270 → 359
    Ig3_FGFR-2; Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor 2 (FGFR2)
    cd05098
    Location:462 → 763
    PTKc_FGFR1; Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 1

  6. XM_063239826.1 → XP_063095896.1  fibroblast growth factor receptor 1 isoform X1

    UniProtKB/TrEMBL
    H0V817

  7. XM_063239828.1 → XP_063095898.1  fibroblast growth factor receptor 1 isoform X3

  8. XM_023561986.2 → XP_023417754.1  fibroblast growth factor receptor 1 isoform X7

    UniProtKB/TrEMBL
    A0A286XMS2
    Conserved Domains (3) summary
    cd05857
    Location:72 → 156
    Ig2_FGFR; Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor
    cd05858
    Location:179 → 268
    Ig3_FGFR-2; Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor 2 (FGFR2)
    cd05098
    Location:371 → 672
    PTKc_FGFR1; Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 1

  9. XM_063239832.1 → XP_063095902.1  fibroblast growth factor receptor 1 isoform X6

  10. XM_063239831.1 → XP_063095901.1  fibroblast growth factor receptor 1 isoform X5

Nucleotide Protein
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