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Six4 SIX homeobox 4 [ Cavia porcellus (domestic guinea pig) ]

Gene ID: 100718127, updated on 8-Mar-2024

Summary

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Gene symbol
Six4
Gene description
SIX homeobox 4
See related
Ensembl:ENSCPOG00000040202
Gene type
protein coding
RefSeq status
MODEL
Organism
Cavia porcellus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
Orthologs
human mouse all
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Genomic context

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See Six4 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947514.1 (40676744..40689721)
103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176399.1 (5574359..5587385, complement)

NW_026947514.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORD43 Neighboring gene tRNA methyltransferase 5 Neighboring gene MNAT1 component of CDK activating kinase Neighboring gene SIX homeobox 1 Neighboring gene SIX homeobox 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
homeobox protein SIX4
Names
sine oculis-related homeobox 4 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCavPor4.1

Genomic

  1. NW_026947514.1 Reference mCavPor4.1

    Range
    40676744..40689721
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013155321.2 → XP_013010775.1  homeobox protein SIX4 isoform X2

    UniProtKB/TrEMBL
    A0A286XIL2
    Related
    ENSCPOP00000025287.1
    Conserved Domains (2) summary
    cd00086
    Location:206 → 260
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam16878
    Location:86 → 195
    SIX1_SD; Transcriptional regulator, SIX1, N-terminal SD domain

  2. XM_003472511.3 → XP_003472559.1  homeobox protein SIX4 isoform X1

    UniProtKB/TrEMBL
    A0A286XAC1
    Related
    ENSCPOP00000022364.1
    Conserved Domains (2) summary
    cd00086
    Location:214 → 268
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam16878
    Location:94 → 203
    SIX1_SD; Transcriptional regulator, SIX1, N-terminal SD domain

  3. XM_013155322.2 → XP_013010776.1  homeobox protein SIX4 isoform X3

    Conserved Domains (2) summary
    cd00086
    Location:214 → 268
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam16878
    Location:94 → 203
    SIX1_SD; Transcriptional regulator, SIX1, N-terminal SD domain
Nucleotide Protein
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