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PTPRC protein tyrosine phosphatase receptor type C [ Sus scrofa (pig) ]

Gene ID: 100522631, updated on 17-Aug-2024

Summary

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Official Symbol
PTPRCprovided by VGNC
Official Full Name
protein tyrosine phosphatase receptor type Cprovided by VGNC
Primary source
VGNC:VGNC:108280
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as
CD45
Expression
Biased expression in spleen (RPKM 209.7), lung (RPKM 76.6) and 1 other tissue See more
Orthologs
human mouse all
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Genomic context

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See PTPRC in Genome Data Viewer
Location:
chromosome: 10
Exon count:
32
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 10 NC_010452.4 (21482984..21601627)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 10 NC_010452.3 (26308772..26332086)

Chromosome 10 - NC_010452.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106505117 Neighboring gene uncharacterized LOC106505118 Neighboring gene uncharacterized LOC110255652 Neighboring gene microRNA mir-181b-1 Neighboring gene microRNA mir-181a-1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Proteomic and transcriptomic analyses of differential stress/inflammatory responses in mandibular lymph nodes and oropharyngeal tonsils of European wild boars naturally infected with Mycobacterium bovis. Naranjo V, et al. Proteomics, 2007 Jan. PMID 17163576
  2. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  3. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in T cell receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of peptidyl-tyrosine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C
Names
CD45 antigen
receptor-type tyrosine-protein phosphatase C

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010452.4 Reference Sscrofa11.1 Primary Assembly

    Range
    21482984..21601627
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003130596.6 → XP_003130644.5  LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C

    UniProtKB/TrEMBL
    A0A8D1JGT3
    Conserved Domains (5) summary
    smart00194
    Location:915 → 1197
    PTPc; Protein tyrosine phosphatase, catalytic domain
    cd00047
    Location:651 → 882
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:456 → 536
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam12567
    Location:195 → 247
    CD45; Leukocyte receptor CD45
    cl25495
    Location:18 → 182
    Endomucin
Nucleotide Protein
Heading Accession and Version

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