slc12a3 solute carrier family 12 member 3 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: slc12a3provided by Xenbase
Official Full Name: solute carrier family 12 member 3provided by Xenbase
Primary source: Xenbase:XB-GENE-866805
See related: Ensembl:ENSXETG00000019997 AllianceGenome:Xenbase:XB-GENE-866805
Gene type: protein coding
RefSeq status: MODEL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: ncc; tsc; ncct
Summary: Predicted to enable chloride:monoatomic cation symporter activity. Predicted to act upstream of or within chloride transmembrane transport; sodium ion transport; and tube morphogenesis. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Gitelman syndrome and essential hypertension. Orthologous to human SLC12A3 (solute carrier family 12 member 3). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	4	NC_030680.2 (51573333..51602287, complement)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	4	NC_030680.1 (54085004..54114102, complement)

Chromosome 4 - NC_030680.2 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Function	Evidence Code	Pubs
enables chloride:monoatomic cation symporter activity	IEA Inferred from Electronic Annotation more info
enables monoatomic cation transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within chloride transmembrane transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cloaca development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within monoatomic ion transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within pronephric duct morphogenesis	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within sodium ion transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

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The following sections contain reference sequences that belong to a specific genome build. Explain