chrm3 cholinergic receptor, muscarinic 3 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: chrm3provided by Xenbase
Official Full Name: cholinergic receptor, muscarinic 3provided by Xenbase
Primary source: Xenbase:XB-GENE-940647
See related: Ensembl:ENSXETG00000016229 AllianceGenome:Xenbase:XB-GENE-940647
Gene type: protein coding
RefSeq status: MODEL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary: Predicted to enable G protein-coupled acetylcholine receptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway; positive regulation of smooth muscle contraction; and saliva secretion. Predicted to be located in postsynaptic membrane. Human ortholog(s) of this gene implicated in bladder disease; chronic obstructive pulmonary disease; prune belly syndrome; and pulmonary fibrosis. Orthologous to human CHRM3 (cholinergic receptor muscarinic 3). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	5	NC_030681.2 (56429952..56432326)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	5	NC_030681.1 (59938192..59940428)

Chromosome 5 - NC_030681.2 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Function	Evidence Code	Pubs
enables G protein-coupled acetylcholine receptor activity	IEA Inferred from Electronic Annotation more info
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of smooth muscle contraction	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within saliva secretion	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cell junction	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in postsynaptic membrane	IEA Inferred from Electronic Annotation more info
located_in synapse	IEA Inferred from Electronic Annotation more info

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The following sections contain reference sequences that belong to a specific genome build. Explain