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setd2 SET domain containing 2 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100492810, updated on 18-Sep-2024

Summary

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Official Symbol
setd2provided by Xenbase
Official Full Name
SET domain containing 2provided by Xenbase
Primary source
Xenbase:XB-GENE-995488
See related
Ensembl:ENSXETG00000023876
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Orthologs
human mouse all
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Genomic context

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See setd2 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
23
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 6 NC_030682.2 (12340871..12390959)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 6 NC_030682.1 (4261497..4312038, complement)

Chromosome 6 - NC_030682.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101731222 Neighboring gene zeta tubulin Neighboring gene neurotrophin receptor associated death domain Neighboring gene anaphase promoting complex subunit 15

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables histone H3K36 methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within chromatin organization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
histone-lysine N-methyltransferase SETD2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030682.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    12340871..12390959
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031903778.1 → XP_031759638.1  histone-lysine N-methyltransferase SETD2 isoform X2

    UniProtKB/TrEMBL
    A0A6I8SZS5, A0A8J1JP37
    Conserved Domains (7) summary
    smart00570
    Location:1907 → 1961
    AWS; associated with SET domains
    COG5160
    Location:763 → 1089
    ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
    cd19172
    Location:1961 → 2102
    SET_SETD2; SET domain (including post-SET domain) found in SET domain-containing protein 2 (SETD2) and similar proteins
    pfam00397
    Location:2822 → 2851
    WW; WW domain
    pfam08236
    Location:2899 → 2987
    SRI; SRI (Set2 Rpb1 interacting) domain
    NF033839
    Location:960 → 1138
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    NF033845
    Location:329 → 589
    MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB

  2. XM_012964979.3 → XP_012820433.2  histone-lysine N-methyltransferase SETD2 isoform X1

    UniProtKB/TrEMBL
    A0A6I8SKU6, A0A6I8SZS5
    Related
    ENSXETP00000093809.2, ENSXETT00000068337.2
    Conserved Domains (7) summary
    smart00570
    Location:1907 → 1961
    AWS; associated with SET domains
    COG5160
    Location:763 → 1089
    ULP1; Protease, Ulp1 family [Posttranslational modification, protein turnover, chaperones]
    cd19172
    Location:1961 → 2102
    SET_SETD2; SET domain (including post-SET domain) found in SET domain-containing protein 2 (SETD2) and similar proteins
    pfam00397
    Location:2823 → 2852
    WW; WW domain
    pfam08236
    Location:2900 → 2988
    SRI; SRI (Set2 Rpb1 interacting) domain
    NF033839
    Location:960 → 1138
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    NF033845
    Location:329 → 589
    MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB

RNA

  1. XR_004223147.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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