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cryaa crystallin alpha A [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100488185, updated on 4-Nov-2024

Summary

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Official Symbol
cryaaprovided by Xenbase
Official Full Name
crystallin alpha Aprovided by Xenbase
Primary source
Xenbase:XB-GENE-5940571
See related
Ensembl:ENSXETG00000020802 AllianceGenome:Xenbase:XB-GENE-5940571
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary
Predicted to enable pyruvate transmembrane transporter activity. Predicted to be involved in mitochondrial pyruvate transmembrane transport. Predicted to be located in cytoplasm. Predicted to be active in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in cataract 9 multiple types. Orthologous to human CRYAA (crystallin alpha A). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See cryaa in Genome Data Viewer
Location:
chromosome: 2
Exon count:
2
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 2 NC_030678.2 (1518815..1519606)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) Unplaced Scaffold NW_016687487.1 (453..3330)

Chromosome 2 - NC_030678.2Genomic Context describing neighboring genes Neighboring gene glutamine amidotransferase class 1 domain containing 3 Neighboring gene U2 small nuclear RNA auxiliary factor 1 Neighboring gene salt inducible kinase 1 Neighboring gene heat shock transcription factor 2 binding protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables pyruvate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of eye lens IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in mitochondrial pyruvate transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrial inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
alpha-crystallin A chain

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030678.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    1518815..1519606
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031896342.1 → XP_031752202.1  alpha-crystallin A chain

    UniProtKB/TrEMBL
    A0A1B8XSV3, F7DB35
    Related
    ENSXETP00000044922.5, ENSXETT00000044922.5
    Conserved Domains (1) summary
    cl00175
    Location:5 → 89
    alpha-crystallin-Hsps_p23-like; alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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