U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

trpv1 transient receptor potential cation channel, subfamily V, member 1 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100487208, updated on 4-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
trpv1provided by Xenbase
Official Full Name
transient receptor potential cation channel, subfamily V, member 1provided by Xenbase
Primary source
Xenbase:XB-GENE-991320
See related
Ensembl:ENSXETG00000005790 AllianceGenome:Xenbase:XB-GENE-991320
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary
Predicted to enable ATP binding activity; calcium channel activity; and calmodulin binding activity. Predicted to act upstream of or within calcium ion transmembrane transport. Predicted to be located in dendritic spine membrane and postsynaptic membrane. Human ortholog(s) of this gene implicated in migraine. Orthologous to human TRPV1 (transient receptor potential cation channel subfamily V member 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See trpv1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
18
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 2 NC_030678.2 (30588935..30619749, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 2 NC_030678.1 (31934413..31954698)

Chromosome 2 - NC_030678.2Genomic Context describing neighboring genes Neighboring gene aspartoacylase Neighboring gene transient receptor potential cation channel, subfamily V, member 3 Neighboring gene sedoheptulokinase Neighboring gene cystinosin, lysosomal cystine transporter Neighboring gene Tax1 binding protein 3 Neighboring gene hornerin-like

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Molecular cloning and functional characterization of Xenopus tropicalis frog transient receptor potential vanilloid 1 reveal its functional evolution for heat, acid, and capsaicin sensitivities in terrestrial vertebrates. Ohkita M, et al. J Biol Chem, 2012 Jan 20. PMID 22130664, Free PMC Article
  2. Analysis of transient receptor potential ankyrin 1 (TRPA1) in frogs and lizards illuminates both nociceptive heat and chemical sensitivities and coexpression with TRP vanilloid 1 (TRPV1) in ancestral vertebrates. Saito S, et al. J Biol Chem, 2012 Aug 31. PMID 22791718, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Analysis of transient receptor potential ankyrin 1 (TRPA1) in frogs and lizards illuminates both nociceptive heat and chemical sensitivities and coexpression with TRP vanilloid 1 (TRPV1) in ancestral vertebrates.
    Title: Analysis of transient receptor potential ankyrin 1 (TRPA1) in frogs and lizards illuminates both nociceptive heat and chemical sensitivities and coexpression with TRP vanilloid 1 (TRPV1) in ancestral vertebrates.
  2. TRPV1 functions as a heat- and acid-sensitive channel in the ancestor of terrestrial vertebrates.
    Title: Molecular cloning and functional characterization of Xenopus tropicalis frog transient receptor potential vanilloid 1 reveal its functional evolution for heat, acid, and capsaicin sensitivities in terrestrial vertebrates.
Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables calcium channel activity IEA
Inferred from Electronic Annotation
more info
  
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
  
enables monoatomic ion channel activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in dendritic spine membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
transient receptor potential cation channel subfamily V member 1
Names
transient receptor potential vanilloid 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001256592.1 → NP_001243521.1  transient receptor potential cation channel subfamily V member 1

    See identical proteins and their annotated locations for NP_001243521.1

    Status: PROVISIONAL

    Source sequence(s)
    AB682793
    UniProtKB/TrEMBL
    A0A6I8SPL1, H3K2J6
    Conserved Domains (2) summary
    sd00045
    Location:214 → 245
    ANK; ANK repeat [structural motif]
    cl40437
    Location:122 → 768
    TRPV; Transient Receptor Potential channel, Vanilloid subfamily (TRPV)

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030678.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    30588935..30619749 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031895781.1 → XP_031751641.1  transient receptor potential cation channel subfamily V member 1 isoform X1

    UniProtKB/TrEMBL
    A0A6I8T2G1
    Related
    ENSXETP00000101142.2, ENSXETT00000069102.2
    Conserved Domains (2) summary
    sd00045
    Location:214 → 245
    ANK; ANK repeat [structural motif]
    cd22196
    Location:122 → 786
    TRPV1; Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 1

  2. XM_031895783.1 → XP_031751643.1  transient receptor potential cation channel subfamily V member 1 isoform X2

    UniProtKB/TrEMBL
    A0A6I8SPL1, H3K2J6
    Related
    ENSXETP00000093983.2, ENSXETT00000099644.2
    Conserved Domains (2) summary
    sd00045
    Location:214 → 245
    ANK; ANK repeat [structural motif]
    cl40437
    Location:122 → 768
    TRPV; Transient Receptor Potential channel, Vanilloid subfamily (TRPV)

  3. XM_031895782.1 → XP_031751642.1  transient receptor potential cation channel subfamily V member 1 isoform X1

    UniProtKB/TrEMBL
    A0A6I8T2G1
    Conserved Domains (2) summary
    sd00045
    Location:214 → 245
    ANK; ANK repeat [structural motif]
    cd22196
    Location:122 → 786
    TRPV1; Transient Receptor Potential channel, Vanilloid subfamily (TRPV), type 1
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.