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gatad2b GATA zinc finger domain containing 2B [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100486823, updated on 4-Nov-2024

Summary

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Official Symbol
gatad2bprovided by Xenbase
Official Full Name
GATA zinc finger domain containing 2Bprovided by Xenbase
Primary source
Xenbase:XB-GENE-5995517
See related
Ensembl:ENSXETG00000019921 AllianceGenome:Xenbase:XB-GENE-5995517
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary
Predicted to enable sequence-specific DNA binding activity and zinc ion binding activity. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in GAND syndrome. Orthologous to human GATAD2B (GATA zinc finger domain containing 2B). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See gatad2b in Genome Data Viewer
Location:
chromosome: 8
Exon count:
13
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 8 NC_030684.2 (144339662..144369185, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) Unplaced Scaffold NW_016683934.1 (15320..49315, complement)

Chromosome 8 - NC_030684.2Genomic Context describing neighboring genes Neighboring gene integrator complex subunit 3 Neighboring gene solute carrier family 27 member 3 Neighboring gene uncharacterized LOC116406707 Neighboring gene DNA-directed RNA polymerase II subunit RPB1-like Neighboring gene DENN/MADD domain containing 4B Neighboring gene CREB regulated transcription coactivator 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
transcriptional repressor p66-beta

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030684.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    144339662..144369185 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031890632.1 → XP_031746492.1  transcriptional repressor p66-beta

    UniProtKB/TrEMBL
    A0A803KAN5, F6XFN7
    Related
    ENSXETP00000043100.6, ENSXETT00000043100.6
    Conserved Domains (2) summary
    pfam00320
    Location:416 → 450
    GATA; GATA zinc finger
    pfam16563
    Location:157 → 192
    P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2

  2. XM_031890633.1 → XP_031746493.1  transcriptional repressor p66-beta

    UniProtKB/TrEMBL
    A0A803KAN5, F6XFN7
    Conserved Domains (2) summary
    pfam00320
    Location:416 → 450
    GATA; GATA zinc finger
    pfam16563
    Location:157 → 192
    P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2

  3. XM_031890634.1 → XP_031746494.1  transcriptional repressor p66-beta

    UniProtKB/TrEMBL
    A0A803KAN5, F6XFN7
    Conserved Domains (2) summary
    pfam00320
    Location:416 → 450
    GATA; GATA zinc finger
    pfam16563
    Location:157 → 192
    P66_CC; Coiled-coil and interaction region of P66A and P66B with MBD2
Nucleotide Protein Strain
Heading Accession and Version

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