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BACE2 beta-secretase 2 [ Ailuropoda melanoleuca (giant panda) ]

Gene ID: 100477612, updated on 8-Mar-2024

Summary

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Gene symbol
BACE2
Gene description
beta-secretase 2
Locus tag
PANDA_020703
See related
Ensembl:ENSAMEG00000005103
Gene type
protein coding
RefSeq status
MODEL
Organism
Ailuropoda melanoleuca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda
Orthologs
human mouse all
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Genomic context

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See BACE2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
10
Annotation release Status Assembly Chr Location
103 current ASM200744v2 (GCF_002007445.1) 1 NC_048218.1 (4384292..4466610, complement)
102 previous assembly AilMel_1.0 (GCF_000004335.2) Unplaced Scaffold NW_003219523.1 (18032..99008)

Chromosome 1 - NC_048218.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC117801166 Neighboring gene FAM3 metabolism regulating signaling molecule B Neighboring gene uncharacterized LOC117802359 Neighboring gene DS cell adhesion molecule

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The sequence and de novo assembly of the giant panda genome. Li R, et al. Nature, 2010 Jan 21. PMID 20010809, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aspartic-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in amyloid-beta metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in membrane protein ectodomain proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in trans-Golgi network IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
beta-secretase 2
Names
beta-site APP-cleaving enzyme 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ailuropoda melanoleuca Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM200744v2 Primary Assembly

Genomic

  1. NC_048218.1 Reference ASM200744v2 Primary Assembly

    Range
    4384292..4466610 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_034655463.1 → XP_034511354.1  beta-secretase 2

    UniProtKB/TrEMBL
    G1LER0
    Related
    ENSAMEP00000005397.2, ENSAMET00000005619.2
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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