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cacna1d.L calcium channel, voltage-dependent, L type, alpha 1D subunit L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 100462912, updated on 4-Nov-2024

Summary

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Official Symbol
cacna1d.L
Official Full Name
calcium channel, voltage-dependent, L type, alpha 1D subunit L homeolog
Primary source
Xenbase:XB-GENE-6488897
See related
EnsemblRapid:ENSXLAG00005007066 AllianceGenome:Xenbase:XB-GENE-6488897
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
cav1.3; cacna1d; ca(v)1.3
Summary
Is expressed in cardiovascular system; nervous system; sensory system; vestibuloauditory system; and visual system. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human CACNA1D (calcium voltage-gated channel subunit alpha1 D). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See cacna1d.L in Genome Data Viewer
Location:
chromosome: 4L
Exon count:
52
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4L NC_054377.1 (152092855..152255172, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) Unplaced Scaffold NW_016694815.1 (1985923..2149015, complement)

Chromosome 4L - NC_054377.1Genomic Context describing neighboring genes Neighboring gene selenoprotein K L homeolog Neighboring gene choline dehydrogenase L homeolog Neighboring gene mRNA-decapping enzyme 1A Neighboring gene transketolase L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cloning and characterization of voltage-gated calcium channel alpha1 subunits in Xenopus laevis during development. Lewis BB, et al. Dev Dyn, 2009 Nov. PMID 19795515, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
voltage-dependent L-type calcium channel subunit alpha-1D
Names
calcium channel voltage-dependent L type Cav1.3, alpha 1d subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    152092855..152255172 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041590973.1 → XP_041446907.1  voltage-dependent L-type calcium channel subunit alpha-1D isoform X4

    UniProtKB/TrEMBL
    A0A8J1MYE4
    Conserved Domains (2) summary
    smart01062
    Location:1582 → 1612
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    COG5422
    Location:1653 → 1797
    ROM1; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms]

  2. XM_041590979.1 → XP_041446913.1  voltage-dependent L-type calcium channel subunit alpha-1D isoform X10

    UniProtKB/TrEMBL
    A0A8J1N076
    Related
    ENSXLAP00005020502.1, ENSXLAT00005021032.1
    Conserved Domains (2) summary
    smart01062
    Location:1558 → 1588
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    COG5422
    Location:1629 → 1773
    ROM1; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms]

  3. XM_041590980.1 → XP_041446914.1  voltage-dependent L-type calcium channel subunit alpha-1D isoform X11

    UniProtKB/TrEMBL
    A0A8J1MYF4
    Related
    ENSXLAP00005020844.1, ENSXLAT00005021434.1
    Conserved Domains (2) summary
    smart01062
    Location:1558 → 1588
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    COG5422
    Location:1629 → 1773
    ROM1; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms]

  4. XM_041590972.1 → XP_041446906.1  voltage-dependent L-type calcium channel subunit alpha-1D isoform X3

    UniProtKB/TrEMBL
    A0A8J1MZJ5
    Related
    ENSXLAP00005020746.1, ENSXLAT00005021316.1
    Conserved Domains (2) summary
    smart01062
    Location:1582 → 1612
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    COG5422
    Location:1653 → 1797
    ROM1; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms]

  5. XM_041590978.1 → XP_041446912.1  voltage-dependent L-type calcium channel subunit alpha-1D isoform X9

    UniProtKB/TrEMBL
    A0A8J1MYP5
    Related
    ENSXLAP00005020887.1, ENSXLAT00005021485.1
    Conserved Domains (2) summary
    smart01062
    Location:1558 → 1588
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    COG5422
    Location:1629 → 1773
    ROM1; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms]

  6. XM_041590971.1 → XP_041446905.1  voltage-dependent L-type calcium channel subunit alpha-1D isoform X2

    UniProtKB/TrEMBL
    A0A8J1N0Y5
    Conserved Domains (2) summary
    smart01062
    Location:1582 → 1612
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    COG5422
    Location:1653 → 1797
    ROM1; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms]

  7. XM_041590977.1 → XP_041446911.1  voltage-dependent L-type calcium channel subunit alpha-1D isoform X8

    UniProtKB/TrEMBL
    A0A8J1MZK1
    Related
    ENSXLAP00005020769.1, ENSXLAT00005021343.1
    Conserved Domains (2) summary
    smart01062
    Location:1558 → 1588
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    COG5422
    Location:1629 → 1773
    ROM1; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms]

  8. XM_041590975.1 → XP_041446909.1  voltage-dependent L-type calcium channel subunit alpha-1D isoform X6

    UniProtKB/TrEMBL
    A0A8J1MYE9
    Conserved Domains (2) summary
    smart01062
    Location:1571 → 1601
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    COG5422
    Location:1642 → 1786
    ROM1; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms]

  9. XM_041590976.1 → XP_041446910.1  voltage-dependent L-type calcium channel subunit alpha-1D isoform X7

    UniProtKB/TrEMBL
    A0A8J1N0Z3
    Conserved Domains (2) summary
    smart01062
    Location:1569 → 1599
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    COG5422
    Location:1640 → 1784
    ROM1; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms]

  10. XM_041590974.1 → XP_041446908.1  voltage-dependent L-type calcium channel subunit alpha-1D isoform X5

    UniProtKB/TrEMBL
    A0A8J1N071
    Conserved Domains (1) summary
    smart01062
    Location:1582 → 1612
    Ca_chan_IQ; Voltage gated calcium channel IQ domain

  11. XM_041590970.1 → XP_041446904.1  voltage-dependent L-type calcium channel subunit alpha-1D isoform X1

    UniProtKB/TrEMBL
    A0A8J1MYE4
    Conserved Domains (2) summary
    smart01062
    Location:1582 → 1612
    Ca_chan_IQ; Voltage gated calcium channel IQ domain
    COG5422
    Location:1653 → 1797
    ROM1; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms]
Nucleotide Protein Strain
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