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cenpc centromere protein C [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100379894, updated on 4-Nov-2024

Summary

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Official Symbol
cenpcprovided by Xenbase
Official Full Name
centromere protein Cprovided by Xenbase
Primary source
Xenbase:XB-GENE-6452278
See related
Ensembl:ENSXETG00000031099 AllianceGenome:Xenbase:XB-GENE-6452278
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
mif2; hcp-4; cenp-c; cenpc1
Summary
Predicted to enable centromeric DNA binding activity. Predicted to act upstream of or within kinetochore assembly. Predicted to be located in kinetochore and nucleus. Human ortholog(s) of this gene implicated in CREST syndrome and liver cirrhosis. Orthologous to human CENPC (centromere protein C). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See cenpc in Genome Data Viewer
Location:
chromosome: 1
Exon count:
19
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 1 NC_030677.2 (82799410..82856979)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 1 NC_030677.1 (89089049..89140053)

Chromosome 1 - NC_030677.2Genomic Context describing neighboring genes Neighboring gene ubiquitin-like modifier activating enzyme 6 Neighboring gene signal transducing adaptor family member 1 Neighboring gene EPH receptor A5 Neighboring gene PEAK1 related, kinase-activating pseudokinase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables centromeric DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within kinetochore assembly IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chromosome, centromeric region IEA
Inferred from Electronic Annotation
more info
  
located_in kinetochore IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
centromere protein C
Names
centromere protein C 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030677.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    82799410..82856979
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012955392.3 → XP_012810846.2  centromere protein C isoform X3

    UniProtKB/TrEMBL
    A0A803K7D8, A0A8J0SDQ1

  2. XM_012955387.3 → XP_012810841.2  centromere protein C isoform X1

    UniProtKB/TrEMBL
    A0A803K6J5, F6PXD7
    Related
    ENSXETP00000054728.4, ENSXETT00000054728.4
    Conserved Domains (1) summary
    cl40423
    Location:1299 → 1375
    cupin_RmlC-like; RmlC-like cupin superfamily

  3. XM_002936462.5 → XP_002936508.3  centromere protein C isoform X2

    UniProtKB/TrEMBL
    A0A803K6J5, A0A8J0QS85
    Related
    ENSXETP00000115986.1, ENSXETT00000113333.1
    Conserved Domains (1) summary
    cl40423
    Location:1298 → 1374
    cupin_RmlC-like; RmlC-like cupin superfamily
Nucleotide Protein Strain
Heading Accession and Version

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