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APOC3 apolipoprotein C3 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100342936, updated on 8-Mar-2024

Summary

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Gene symbol
APOC3
Gene description
apolipoprotein C3
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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Genomic context

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See APOC3 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 1 NC_067374.1 (113567203..113568671, complement)

Chromosome 1 - NC_067374.1Genomic Context describing neighboring genes Neighboring gene SIK family kinase 3 Neighboring gene ubiquitin carboxyl-terminal hydrolase isozyme L3-like Neighboring gene apolipoprotein A1 Neighboring gene apolipoprotein A4 Neighboring gene apolipoprotein A5

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_067374.1 Chromosome 1 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables high-density lipoprotein particle receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables lipase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phospholipid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cholesterol homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipoprotein metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of high-density lipoprotein particle clearance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of lipoprotein lipase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of low-density lipoprotein particle clearance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of triglyceride catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of very-low-density lipoprotein particle clearance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in triglyceride homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of chylomicron IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of intermediate-density lipoprotein particle IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of spherical high-density lipoprotein particle IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of very-low-density lipoprotein particle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
apolipoprotein C-III

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NC_067374.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    113567203..113568671 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002708371.4 → XP_002708417.1  apolipoprotein C-III

    Conserved Domains (1) summary
    pfam05778
    Location:27 → 93
    Apo-CIII; Apolipoprotein CIII (Apo-CIII)
Nucleotide Protein
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Gene LinkOut

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