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sox14.S SRY-box 14 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 100337614, updated on 4-Nov-2024

Summary

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Official Symbol
sox14.S
Official Full Name
SRY-box 14 S homeolog
Primary source
Xenbase:XB-GENE-6458188
Locus tag
XELAEV_18030011mg
See related
EnsemblRapid:ENSXLAG00005033126 AllianceGenome:Xenbase:XB-GENE-6458188
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Summary
Predicted to enable sequence-specific DNA binding activity. Acts upstream of or within nervous system development. Predicted to be located in nucleus. Is expressed in nervous system. Orthologous to human SOX14 (SRY-box transcription factor 14). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See sox14.S in Genome Data Viewer
Location:
chromosome: 5S
Exon count:
1
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5S NC_054380.1 (119338345..119339064, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5S NC_030733.1 (112631886..112632605, complement)

Chromosome 5S - NC_054380.1Genomic Context describing neighboring genes Neighboring gene DAZ interacting zinc finger protein 1-like S homeolog Neighboring gene claudin 18 S homeolog Neighboring gene interleukin-20 receptor subunit beta Neighboring gene NCK adaptor protein 1 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cloning and developmental expression of the soxB2 genes, sox14 and sox21, during Xenopus laevis embryogenesis. Cunningham DD, et al. Int J Dev Biol, 2008. PMID 18956331, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within anatomical structure morphogenesis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cell differentiation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within negative regulation of DNA-templated transcription ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within nervous system development IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
transcription factor Sox-14
Names
SRY (sex determining region Y)-box 14
SRY-box containing gene 14
sox14

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001172214.1 → NP_001165685.1  transcription factor Sox-14

    See identical proteins and their annotated locations for NP_001165685.1

    Status: PROVISIONAL

    Source sequence(s)
    EU403425
    UniProtKB/Swiss-Prot
    B0ZTE2
    UniProtKB/TrEMBL
    A0A974CSX7
    Related
    ENSXLAP00005099075.1, ENSXLAT00005100934.1
    Conserved Domains (2) summary
    cd01388
    Location:7 → 78
    SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
    pfam12336
    Location:77 → 95
    SOXp; SOX transcription factor

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054380.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    119338345..119339064 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B0ZTE2.1 GenPept UniProtKB/Swiss-Prot:B0ZTE2

Gene LinkOut

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