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dchs1a dachsous cadherin-related 1a [ Danio rerio (zebrafish) ]

Gene ID: 100334632, updated on 2-Nov-2024

Summary

Official Symbol
dchs1aprovided by ZNC
Official Full Name
dachsous cadherin-related 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-120410-3
See related
Ensembl:ENSDARG00000070025 AllianceGenome:ZFIN:ZDB-GENE-120410-3
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable calcium ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to act upstream of or within homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in Van Maldergem syndrome 1 and mitral valve prolapse. Orthologous to human DCHS1 (dachsous cadherin-related 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See dchs1a in Genome Data Viewer
Location:
chromosome: 15
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (31997396..32197821)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (32139407..32339859)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene furry homolog a (Drosophila) Neighboring gene BRCA2 DNA repair associated Neighboring gene uncharacterized LOC137487768 Neighboring gene ADP-ribosylation factor interacting protein 2a Neighboring gene FH2 domain containing 4

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cell adhesion IEA
Inferred from Electronic Annotation
more info
 
involved_in cell-cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within homophilic cell adhesion via plasma membrane adhesion molecules IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protocadherin-16
Names
dachsous 1a

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    31997396..32197821
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002664651.7XP_002664697.2  protocadherin-16

    UniProtKB/TrEMBL
    A0A8M1RKP3, X1WDW2
    Related
    ENSDARP00000128412.1, ENSDART00000153791.3
    Conserved Domains (2) summary
    cd11304
    Location:16471741
    Cadherin_repeat; Cadherin tandem repeat domain
    pfam01049
    Location:31093156
    Cadherin_C; Cadherin cytoplasmic region