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tti2 TELO2 interacting protein 2 [ Danio rerio (zebrafish) ]

Gene ID: 100334230, updated on 2-Nov-2024

Summary

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Official Symbol
tti2provided by ZNC
Official Full Name
TELO2 interacting protein 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-110411-25
See related
Ensembl:ENSDARG00000073773 AllianceGenome:ZFIN:ZDB-GENE-110411-25
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch73-316k5.2
Summary
Predicted to be part of TTT Hsp90 cochaperone complex. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 39. Orthologous to human TTI2 (TELO2 interacting protein 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See tti2 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (45381331..45395244)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (45373444..45387365)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene poly(A) binding protein, cytoplasmic 1-like Neighboring gene charged multivesicular body protein 4Bb Neighboring gene MAK16 homolog (S. cerevisiae) Neighboring gene U1 spliceosomal RNA Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
part_of TTT Hsp90 cochaperone complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of TTT Hsp90 cochaperone complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
TELO2-interacting protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    45381331..45395244
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002663205.6 → XP_002663251.1  TELO2-interacting protein 2

    UniProtKB/TrEMBL
    A0A8M1RR58, E7F592
    Related
    ENSDARP00000100891.3, ENSDART00000110364.4
    Conserved Domains (1) summary
    pfam10521
    Location:148 → 372
    DUF2454; Protein of unknown function (DUF2454)
Nucleotide Protein Strain
Heading Accession and Version

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