rflnb refilin B [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rflnbprovided by ZNC
Official Full Name: refilin Bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-090409-1
See related: Ensembl:ENSDARG00000093931 AllianceGenome:ZFIN:ZDB-GENE-090409-1
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fam101b
Summary: Predicted to enable filamin binding activity. Predicted to be involved in several processes, including actin filament bundle organization; negative regulation of bone mineralization involved in bone maturation; and negative regulation of chondrocyte development. Predicted to act upstream of or within regulation of chondrocyte development. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be active in actin filament bundle. Orthologous to human RFLNB (refilin B). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 15

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	15	NC_007126.7 (25096032..25099679, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	15	NC_007126.6 (25160772..25164441, complement)

Chromosome 15 - NC_007126.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

fb77d11.x1 (e-PCR)
- UniSTS:191368

fb77d11.x1 (e-PCR)
- UniSTS:191369

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables filamin binding	IBA Inferred from Biological aspect of Ancestor more info
enables filamin binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in actin filament bundle organization	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within actin filament bundle organization	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of bone mineralization involved in bone maturation	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of chondrocyte development	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of chondrocyte development	IEA Inferred from Electronic Annotation more info
involved_in skeletal system morphogenesis	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in actin filament bundle	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: refilin-B

Names: family with sequence similarity 101, member B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.