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e4f1.S E4F transcription factor 1 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 100190769, updated on 4-Nov-2024

Summary

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Official Symbol
e4f1.S
Official Full Name
E4F transcription factor 1 S homeolog
Primary source
Xenbase:XB-GENE-6018390
Locus tag
XELAEV_18047738mg
See related
EnsemblRapid:ENSXLAG00005010310 AllianceGenome:Xenbase:XB-GENE-6018390
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
e4f1
Summary
Predicted to enable DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and metal ion binding activity. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Orthologous to human E4F1 (E4F transcription factor 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See e4f1.S in Genome Data Viewer
Location:
chromosome: 9_10S
Exon count:
12
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10S NC_054388.1 (102608209..102635293, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10S NC_030741.1 (95986379..96015472, complement)

Chromosome 9_10S - NC_054388.1Genomic Context describing neighboring genes Neighboring gene BRICHOS domain containing 5 S homeolog Neighboring gene glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein S homeolog Neighboring gene uncharacterized LOC108702432 Neighboring gene phosphoglycolate phosphatase S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
E4F transcription factor 1 S homeolog; transcription factor E4F1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054388.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    102608209..102635293 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018237131.2 → XP_018092620.1  transcription factor E4F1 isoform X2

    UniProtKB/TrEMBL
    A0A8J0U018
    Related
    ENSXLAP00005030402.1, ENSXLAT00005031159.1

  2. XM_041578152.1 → XP_041434086.1  transcription factor E4F1 isoform X1

    UniProtKB/TrEMBL
    A0A8J1LYG9
    Related
    ENSXLAP00005030397.1, ENSXLAT00005031154.1
    Conserved Domains (2) summary
    COG5189
    Location:363 → 425
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:376 → 396
    ZF_C2H2; C2H2 Zn finger [structural motif]

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001135223.1: Suppressed sequence

    Description
    NM_001135223.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein Strain
Heading Accession and Version

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