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cdk19 cyclin dependent kinase 19 [ Danio rerio (zebrafish) ]

Gene ID: 100149670, updated on 2-Nov-2024

Summary

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Official Symbol
cdk19provided by ZNC
Official Full Name
cyclin dependent kinase 19provided by ZNC
Primary source
ZFIN:ZDB-GENE-040724-19
See related
Ensembl:ENSDARG00000043858 AllianceGenome:ZFIN:ZDB-GENE-040724-19
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cdc2l6; si:ch211-257g8.1
Summary
Predicted to enable protein serine/threonine kinase activity. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytosol and nucleus. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 87. Orthologous to human CDK19 (cyclin dependent kinase 19). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See cdk19 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (2878248..2949156, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (2862383..2936644, complement)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene synaptotagmin binding, cytoplasmic RNA interacting protein Neighboring gene 5-hydroxytryptamine receptor 1E Neighboring gene adenosylmethionine decarboxylase 1 Neighboring gene peptidylprolyl isomerase (cyclophilin)-like 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  2. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables cyclin-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
cell division protein kinase 19; cyclin-dependent kinase 19
Names
cell division cycle 2-like 6 (CDK8-like)
XP_001923353.4
XP_021329029.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    2878248..2949156 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001923318.8 → XP_001923353.4  cyclin-dependent kinase 19 isoform X1

    UniProtKB/TrEMBL
    A0A8M1QLR0, F1QKS1
    Related
    ENSDARP00000095438.4, ENSDART00000104667.5
    Conserved Domains (1) summary
    cd07867
    Location:18 → 335
    STKc_CDC2L6; Catalytic domain of Serine/Threonine Kinase, Cell Division Cycle 2-like 6

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395060.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    708..49434 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021473354.2 → XP_021329029.1  cyclin-dependent kinase 19 isoform X2

    UniProtKB/TrEMBL
    A0A8M1QLR0, F1QKS1
    Conserved Domains (1) summary
    cd07867
    Location:18 → 335
    STKc_CDC2L6; Catalytic domain of Serine/Threonine Kinase, Cell Division Cycle 2-like 6
Nucleotide Protein Strain
Heading Accession and Version

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