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macf1 microtubule actin crosslinking factor 1 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100127846, updated on 17-Aug-2024

Summary

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Official Symbol
macf1provided by Xenbase
Official Full Name
microtubule actin crosslinking factor 1provided by Xenbase
Primary source
Xenbase:XB-GENE-494799
See related
Ensembl:ENSXETG00000007367
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
acf7; macf; ofc4; abp620
Orthologs
human mouse all
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Genomic context

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See macf1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
107
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 2 NC_030678.2 (90472181..90655821)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 2 NC_030678.1 (86346992..86530139)

Chromosome 2 - NC_030678.2Genomic Context describing neighboring genes Neighboring gene ornithine decarboxylase-like Neighboring gene NADH:ubiquinone oxidoreductase subunit S5 Neighboring gene vav guanine nucleotide exchange factor 1 Neighboring gene alpha-L-fucosidase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
  
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
  
enables structural molecule activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in intermediate filament cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within intermediate filament cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of focal adhesion assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of microtubule-based process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in wound healing IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
colocalizes_with intermediate filament IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in microtubule IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
microtubule-actin cross-linking factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030678.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    90472181..90655821
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002940018.5 → XP_002940064.3  microtubule-actin cross-linking factor 1 isoform X1

    UniProtKB/TrEMBL
    A0A6I8QG99, A0A8J0QWE7
    Conserved Domains (13) summary
    smart00243
    Location:7139 → 7214
    GAS2; Growth-Arrest-Specific Protein 2 Domain
    smart00150
    Location:6909 → 7030
    SPEC; Spectrin repeats
    PHA03307
    Location:7289 → 7455
    PHA03307; transcriptional regulator ICP4; Provisional
    COG0419
    Location:3321 → 3890
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:4167 → 4960
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00051
    Location:7064 → 7126
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00176
    Location:6687 → 6899
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:1790 → 1829
    Plectin; Plectin repeat
    pfam17902
    Location:881 → 947
    SH3_10; SH3 domain
    pfam18373
    Location:982 → 1061
    Spectrin_like; Spectrin like domain
    cd21188
    Location:71 → 209
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:220 → 326
    CH_SF; calponin homology (CH) domain superfamily
    cl02488
    Location:3410 → 3652
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  2. XM_031896938.1 → XP_031752798.1  microtubule-actin cross-linking factor 1 isoform X10

    UniProtKB/TrEMBL
    A0A6I8RHJ0, A0A8J1J4J9
    Conserved Domains (14) summary
    smart00243
    Location:7139 → 7214
    GAS2; Growth-Arrest-Specific Protein 2 Domain
    smart00150
    Location:6909 → 7030
    SPEC; Spectrin repeats
    PHA03307
    Location:7287 → 7411
    PHA03307; transcriptional regulator ICP4; Provisional
    COG0419
    Location:3321 → 3890
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:4838 → 5131
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG3096
    Location:4595 → 4810
    MukB; Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Escherichia coli str. K-12 substr. MG1655 [Cell cycle control, cell division, chromosome partitioning]
    cd00051
    Location:7064 → 7126
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00176
    Location:6687 → 6899
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:1790 → 1829
    Plectin; Plectin repeat
    pfam17902
    Location:881 → 947
    SH3_10; SH3 domain
    pfam18373
    Location:982 → 1061
    Spectrin_like; Spectrin like domain
    cd21188
    Location:71 → 209
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:220 → 326
    CH_SF; calponin homology (CH) domain superfamily
    cl02488
    Location:3410 → 3652
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  3. XM_031896935.1 → XP_031752795.1  microtubule-actin cross-linking factor 1 isoform X5

    UniProtKB/TrEMBL
    A0A6I8QG99, A0A8J1J6Z1
    Conserved Domains (13) summary
    smart00243
    Location:7139 → 7217
    GAS2; Growth-Arrest-Specific Protein 2 Domain
    smart00150
    Location:6909 → 7030
    SPEC; Spectrin repeats
    PHA03307
    Location:7272 → 7438
    PHA03307; transcriptional regulator ICP4; Provisional
    COG0419
    Location:3320 → 3890
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:4167 → 4960
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00051
    Location:7064 → 7126
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00176
    Location:6687 → 6899
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:1790 → 1829
    Plectin; Plectin repeat
    pfam17902
    Location:881 → 947
    SH3_10; SH3 domain
    pfam18373
    Location:982 → 1061
    Spectrin_like; Spectrin like domain
    cd21188
    Location:71 → 209
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:220 → 326
    CH_SF; calponin homology (CH) domain superfamily
    cl02488
    Location:3410 → 3652
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  4. XM_031896939.1 → XP_031752799.1  microtubule-actin cross-linking factor 1 isoform X12

    UniProtKB/TrEMBL
    A0A6I8RHJ0, A0A8J1J4I9
    Conserved Domains (14) summary
    smart00243
    Location:7139 → 7217
    GAS2; Growth-Arrest-Specific Protein 2 Domain
    smart00150
    Location:6909 → 7030
    SPEC; Spectrin repeats
    PHA03307
    Location:7270 → 7394
    PHA03307; transcriptional regulator ICP4; Provisional
    COG0419
    Location:3320 → 3890
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:4838 → 5131
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG3096
    Location:4595 → 4810
    MukB; Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Escherichia coli str. K-12 substr. MG1655 [Cell cycle control, cell division, chromosome partitioning]
    cd00051
    Location:7064 → 7126
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00176
    Location:6687 → 6899
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:1790 → 1829
    Plectin; Plectin repeat
    pfam17902
    Location:881 → 947
    SH3_10; SH3 domain
    pfam18373
    Location:982 → 1061
    Spectrin_like; Spectrin like domain
    cd21188
    Location:71 → 209
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:220 → 326
    CH_SF; calponin homology (CH) domain superfamily
    cl02488
    Location:3410 → 3652
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  5. XM_031896934.1 → XP_031752794.1  microtubule-actin cross-linking factor 1 isoform X3

    UniProtKB/TrEMBL
    A0A6I8QG99, A0A8J1J4I4
    Conserved Domains (14) summary
    smart00243
    Location:7139 → 7208
    GAS2; Growth-Arrest-Specific Protein 2 Domain
    smart00150
    Location:6909 → 7030
    SPEC; Spectrin repeats
    PHA03307
    Location:7283 → 7449
    PHA03307; transcriptional regulator ICP4; Provisional
    COG0419
    Location:3320 → 3890
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:4838 → 5131
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG3096
    Location:4595 → 4810
    MukB; Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Escherichia coli str. K-12 substr. MG1655 [Cell cycle control, cell division, chromosome partitioning]
    cd00051
    Location:7064 → 7126
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00176
    Location:6687 → 6899
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:1790 → 1829
    Plectin; Plectin repeat
    pfam17902
    Location:881 → 947
    SH3_10; SH3 domain
    pfam18373
    Location:982 → 1061
    Spectrin_like; Spectrin like domain
    cd21188
    Location:71 → 209
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:220 → 326
    CH_SF; calponin homology (CH) domain superfamily
    cl02488
    Location:3410 → 3652
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  6. XM_031896940.1 → XP_031752800.1  microtubule-actin cross-linking factor 1 isoform X13

    UniProtKB/TrEMBL
    A0A6I8RHJ0, A0A8J1J6Z7
    Conserved Domains (14) summary
    smart00243
    Location:7139 → 7211
    GAS2; Growth-Arrest-Specific Protein 2 Domain
    smart00150
    Location:6909 → 7030
    SPEC; Spectrin repeats
    PHA03307
    Location:7264 → 7388
    PHA03307; transcriptional regulator ICP4; Provisional
    COG0419
    Location:3320 → 3890
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:4838 → 5131
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG3096
    Location:4595 → 4810
    MukB; Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Escherichia coli str. K-12 substr. MG1655 [Cell cycle control, cell division, chromosome partitioning]
    cd00051
    Location:7064 → 7126
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00176
    Location:6687 → 6899
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:1790 → 1829
    Plectin; Plectin repeat
    pfam17902
    Location:881 → 947
    SH3_10; SH3 domain
    pfam18373
    Location:982 → 1061
    Spectrin_like; Spectrin like domain
    cd21188
    Location:71 → 209
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:220 → 326
    CH_SF; calponin homology (CH) domain superfamily
    cl02488
    Location:3410 → 3652
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  7. XM_031896933.1 → XP_031752793.1  microtubule-actin cross-linking factor 1 isoform X2

    UniProtKB/TrEMBL
    A0A6I8QG99, A0A8J1J4J4
    Conserved Domains (13) summary
    smart00243
    Location:7136 → 7211
    GAS2; Growth-Arrest-Specific Protein 2 Domain
    smart00150
    Location:6906 → 7027
    SPEC; Spectrin repeats
    PHA03307
    Location:7286 → 7452
    PHA03307; transcriptional regulator ICP4; Provisional
    COG0419
    Location:3321 → 3890
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:4167 → 4960
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00051
    Location:7061 → 7123
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00176
    Location:6684 → 6896
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:1790 → 1829
    Plectin; Plectin repeat
    pfam17902
    Location:881 → 947
    SH3_10; SH3 domain
    pfam18373
    Location:982 → 1061
    Spectrin_like; Spectrin like domain
    cd21188
    Location:71 → 209
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:220 → 326
    CH_SF; calponin homology (CH) domain superfamily
    cl02488
    Location:3410 → 3652
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  8. XM_031896936.1 → XP_031752796.1  microtubule-actin cross-linking factor 1 isoform X6

    UniProtKB/TrEMBL
    A0A6I8QG99, A0A8J1J7Z8
    Conserved Domains (13) summary
    smart00243
    Location:7136 → 7214
    GAS2; Growth-Arrest-Specific Protein 2 Domain
    smart00150
    Location:6906 → 7027
    SPEC; Spectrin repeats
    PHA03307
    Location:7269 → 7435
    PHA03307; transcriptional regulator ICP4; Provisional
    COG0419
    Location:3320 → 3890
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:4167 → 4960
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00051
    Location:7061 → 7123
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00176
    Location:6684 → 6896
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:1790 → 1829
    Plectin; Plectin repeat
    pfam17902
    Location:881 → 947
    SH3_10; SH3 domain
    pfam18373
    Location:982 → 1061
    Spectrin_like; Spectrin like domain
    cd21188
    Location:71 → 209
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:220 → 326
    CH_SF; calponin homology (CH) domain superfamily
    cl02488
    Location:3410 → 3652
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  9. XM_031896941.1 → XP_031752801.1  microtubule-actin cross-linking factor 1 isoform X14

    UniProtKB/TrEMBL
    A0A6I8QG99, A0A8J1J804
    Conserved Domains (13) summary
    smart00243
    Location:7030 → 7105
    GAS2; Growth-Arrest-Specific Protein 2 Domain
    smart00150
    Location:6800 → 6921
    SPEC; Spectrin repeats
    PHA03307
    Location:7180 → 7346
    PHA03307; transcriptional regulator ICP4; Provisional
    COG0419
    Location:3321 → 3890
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG3096
    Location:4595 → 4810
    MukB; Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Escherichia coli str. K-12 substr. MG1655 [Cell cycle control, cell division, chromosome partitioning]
    cd00051
    Location:6955 → 7017
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00176
    Location:6578 → 6790
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:1790 → 1829
    Plectin; Plectin repeat
    pfam17902
    Location:881 → 947
    SH3_10; SH3 domain
    pfam18373
    Location:982 → 1061
    Spectrin_like; Spectrin like domain
    cd21188
    Location:71 → 209
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:220 → 326
    CH_SF; calponin homology (CH) domain superfamily
    cl02488
    Location:3410 → 3652
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  10. XM_031896943.1 → XP_031752803.1  microtubule-actin cross-linking factor 1 isoform X16

    UniProtKB/TrEMBL
    A0A6I8RHJ0, A0A8J1J4K3
    Conserved Domains (13) summary
    smart00243
    Location:7030 → 7102
    GAS2; Growth-Arrest-Specific Protein 2 Domain
    smart00150
    Location:6800 → 6921
    SPEC; Spectrin repeats
    PHA03307
    Location:7155 → 7279
    PHA03307; transcriptional regulator ICP4; Provisional
    COG0419
    Location:3320 → 3890
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG3096
    Location:4595 → 4810
    MukB; Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Escherichia coli str. K-12 substr. MG1655 [Cell cycle control, cell division, chromosome partitioning]
    cd00051
    Location:6955 → 7017
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00176
    Location:6578 → 6790
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:1790 → 1829
    Plectin; Plectin repeat
    pfam17902
    Location:881 → 947
    SH3_10; SH3 domain
    pfam18373
    Location:982 → 1061
    Spectrin_like; Spectrin like domain
    cd21188
    Location:71 → 209
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:220 → 326
    CH_SF; calponin homology (CH) domain superfamily
    cl02488
    Location:3410 → 3652
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  11. XM_031896942.1 → XP_031752802.1  microtubule-actin cross-linking factor 1 isoform X15

    UniProtKB/TrEMBL
    A0A6I8QG99, A0A8J1J4K4
    Conserved Domains (13) summary
    smart00243
    Location:7027 → 7102
    GAS2; Growth-Arrest-Specific Protein 2 Domain
    smart00150
    Location:6797 → 6918
    SPEC; Spectrin repeats
    PHA03307
    Location:7177 → 7343
    PHA03307; transcriptional regulator ICP4; Provisional
    COG0419
    Location:3321 → 3890
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG3096
    Location:4595 → 4810
    MukB; Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Escherichia coli str. K-12 substr. MG1655 [Cell cycle control, cell division, chromosome partitioning]
    cd00051
    Location:6952 → 7014
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00176
    Location:6575 → 6787
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:1790 → 1829
    Plectin; Plectin repeat
    pfam17902
    Location:881 → 947
    SH3_10; SH3 domain
    pfam18373
    Location:982 → 1061
    Spectrin_like; Spectrin like domain
    cd21188
    Location:71 → 209
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:220 → 326
    CH_SF; calponin homology (CH) domain superfamily
    cl02488
    Location:3410 → 3652
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  12. XM_031896944.1 → XP_031752804.1  microtubule-actin cross-linking factor 1 isoform X18

    UniProtKB/TrEMBL
    A0A8J1J4J6, F6XSC1
    Conserved Domains (12) summary
    smart00243
    Location:5169 → 5244
    GAS2; Growth-Arrest-Specific Protein 2 Domain
    smart00150
    Location:4939 → 5060
    SPEC; Spectrin repeats
    PHA03307
    Location:5319 → 5485
    PHA03307; transcriptional regulator ICP4; Provisional
    COG1196
    Location:2197 → 2990
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00051
    Location:5094 → 5156
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00176
    Location:4717 → 4929
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam15921
    Location:1254 → 1870
    CCDC158; Coiled-coil domain-containing protein 158
    pfam17902
    Location:881 → 947
    SH3_10; SH3 domain
    pfam18373
    Location:982 → 1061
    Spectrin_like; Spectrin like domain
    cd21188
    Location:71 → 209
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:220 → 326
    CH_SF; calponin homology (CH) domain superfamily
    cl02488
    Location:1475 → 1681
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  13. XM_012957426.3 → XP_012812880.2  microtubule-actin cross-linking factor 1 isoform X8

    UniProtKB/TrEMBL
    A0A6I8R000, A0A8J0SGF8
    Conserved Domains (13) summary
    smart00243
    Location:7105 → 7180
    GAS2; Growth-Arrest-Specific Protein 2 Domain
    smart00150
    Location:6875 → 6996
    SPEC; Spectrin repeats
    PHA03307
    Location:7255 → 7421
    PHA03307; transcriptional regulator ICP4; Provisional
    COG0419
    Location:3287 → 3856
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:4133 → 4926
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00051
    Location:7030 → 7092
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00176
    Location:6653 → 6865
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:1756 → 1795
    Plectin; Plectin repeat
    pfam17902
    Location:847 → 913
    SH3_10; SH3 domain
    pfam18373
    Location:948 → 1027
    Spectrin_like; Spectrin like domain
    cd21188
    Location:71 → 175
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:186 → 292
    CH_SF; calponin homology (CH) domain superfamily
    cl02488
    Location:3376 → 3618
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  14. XM_031896947.1 → XP_031752807.1  microtubule-actin cross-linking factor 1 isoform X23

    UniProtKB/TrEMBL
    A0A6I8R000, A0A8J1J4K8
    Conserved Domains (13) summary
    smart00243
    Location:7102 → 7180
    GAS2; Growth-Arrest-Specific Protein 2 Domain
    smart00150
    Location:6872 → 6993
    SPEC; Spectrin repeats
    PHA03307
    Location:7235 → 7401
    PHA03307; transcriptional regulator ICP4; Provisional
    COG0419
    Location:3287 → 3856
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:4133 → 4926
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00051
    Location:7027 → 7089
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00176
    Location:6650 → 6862
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:1756 → 1795
    Plectin; Plectin repeat
    pfam17902
    Location:847 → 913
    SH3_10; SH3 domain
    pfam18373
    Location:948 → 1027
    Spectrin_like; Spectrin like domain
    cd21188
    Location:71 → 175
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:186 → 292
    CH_SF; calponin homology (CH) domain superfamily
    cl02488
    Location:3376 → 3618
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  15. XM_031896946.1 → XP_031752806.1  microtubule-actin cross-linking factor 1 isoform X21

    UniProtKB/TrEMBL
    A0A6I8RHJ0, A0A8J1J809
    Conserved Domains (13) summary
    smart00243
    Location:6996 → 7068
    GAS2; Growth-Arrest-Specific Protein 2 Domain
    smart00150
    Location:6766 → 6887
    SPEC; Spectrin repeats
    PHA03307
    Location:7121 → 7245
    PHA03307; transcriptional regulator ICP4; Provisional
    COG0419
    Location:3286 → 3856
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG3096
    Location:4561 → 4776
    MukB; Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Escherichia coli str. K-12 substr. MG1655 [Cell cycle control, cell division, chromosome partitioning]
    cd00051
    Location:6921 → 6983
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00176
    Location:6544 → 6756
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:1756 → 1795
    Plectin; Plectin repeat
    pfam17902
    Location:847 → 913
    SH3_10; SH3 domain
    pfam18373
    Location:948 → 1027
    Spectrin_like; Spectrin like domain
    cd21188
    Location:71 → 175
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:186 → 292
    CH_SF; calponin homology (CH) domain superfamily
    cl02488
    Location:3376 → 3618
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  16. XM_031896948.1 → XP_031752808.1  microtubule-actin cross-linking factor 1 isoform X24

    UniProtKB/TrEMBL
    A0A6I8R000, A0A8J1J4K9
    Conserved Domains (13) summary
    smart00243
    Location:6993 → 7068
    GAS2; Growth-Arrest-Specific Protein 2 Domain
    smart00150
    Location:6763 → 6884
    SPEC; Spectrin repeats
    PHA03307
    Location:7143 → 7309
    PHA03307; transcriptional regulator ICP4; Provisional
    COG3096
    Location:4561 → 4776
    MukB; Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Escherichia coli str. K-12 substr. MG1655 [Cell cycle control, cell division, chromosome partitioning]
    cd00051
    Location:6918 → 6980
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00176
    Location:6541 → 6753
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    TIGR02168
    Location:3287 → 3935
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam00681
    Location:1756 → 1795
    Plectin; Plectin repeat
    pfam17902
    Location:847 → 913
    SH3_10; SH3 domain
    pfam18373
    Location:948 → 1027
    Spectrin_like; Spectrin like domain
    cd21188
    Location:71 → 175
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:186 → 292
    CH_SF; calponin homology (CH) domain superfamily
    cl02488
    Location:3376 → 3618
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  17. XM_031896945.1 → XP_031752805.1  microtubule-actin cross-linking factor 1 isoform X20

    UniProtKB/TrEMBL
    A0A6I8RHJ0, A0A8J1J704
    Conserved Domains (13) summary
    smart00243
    Location:6993 → 7071
    GAS2; Growth-Arrest-Specific Protein 2 Domain
    smart00150
    Location:6763 → 6884
    SPEC; Spectrin repeats
    PHA03307
    Location:7124 → 7248
    PHA03307; transcriptional regulator ICP4; Provisional
    COG0419
    Location:3286 → 3856
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG3096
    Location:4561 → 4776
    MukB; Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Escherichia coli str. K-12 substr. MG1655 [Cell cycle control, cell division, chromosome partitioning]
    cd00051
    Location:6918 → 6980
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00176
    Location:6541 → 6753
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:1756 → 1795
    Plectin; Plectin repeat
    pfam17902
    Location:847 → 913
    SH3_10; SH3 domain
    pfam18373
    Location:948 → 1027
    Spectrin_like; Spectrin like domain
    cd21188
    Location:71 → 175
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:186 → 292
    CH_SF; calponin homology (CH) domain superfamily
    cl02488
    Location:3376 → 3618
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  18. XM_012957432.3 → XP_012812886.2  microtubule-actin cross-linking factor 1 isoform X19

    UniProtKB/TrEMBL
    A0A8J0SFA9, F6XSC1
    Related
    ENSXETP00000016058.5, ENSXETT00000016058.5
    Conserved Domains (12) summary
    smart00243
    Location:5135 → 5210
    GAS2; Growth-Arrest-Specific Protein 2 Domain
    smart00150
    Location:4905 → 5026
    SPEC; Spectrin repeats
    PHA03307
    Location:5285 → 5451
    PHA03307; transcriptional regulator ICP4; Provisional
    COG1196
    Location:2163 → 2956
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00051
    Location:5060 → 5122
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00176
    Location:4683 → 4895
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam15921
    Location:1220 → 1836
    CCDC158; Coiled-coil domain-containing protein 158
    pfam17902
    Location:847 → 913
    SH3_10; SH3 domain
    pfam18373
    Location:948 → 1027
    Spectrin_like; Spectrin like domain
    cd21188
    Location:71 → 175
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:186 → 292
    CH_SF; calponin homology (CH) domain superfamily
    cl02488
    Location:1441 → 1647
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  19. XM_012957435.3 → XP_012812889.2  microtubule-actin cross-linking factor 1 isoform X22

    UniProtKB/TrEMBL
    A0A6I8RNH3, A0A8J0SGG4
    Related
    ENSXETP00000082200.2, ENSXETT00000104920.2
    Conserved Domains (12) summary
    smart00243
    Location:5135 → 5207
    GAS2; Growth-Arrest-Specific Protein 2 Domain
    smart00150
    Location:4905 → 5026
    SPEC; Spectrin repeats
    PHA03307
    Location:5260 → 5384
    PHA03307; transcriptional regulator ICP4; Provisional
    COG1196
    Location:2163 → 2956
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00051
    Location:5060 → 5122
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00176
    Location:4683 → 4895
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam15921
    Location:1220 → 1742
    CCDC158; Coiled-coil domain-containing protein 158
    pfam17902
    Location:847 → 913
    SH3_10; SH3 domain
    pfam18373
    Location:948 → 1027
    Spectrin_like; Spectrin like domain
    cd21188
    Location:71 → 175
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:186 → 292
    CH_SF; calponin homology (CH) domain superfamily
    cl02488
    Location:1441 → 1647
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  20. XM_031896937.1 → XP_031752797.1  microtubule-actin cross-linking factor 1 isoform X7

    UniProtKB/TrEMBL
    A0A6I8QG99, A0A8J1J4K0
    Conserved Domains (14) summary
    smart00243
    Location:7139 → 7211
    GAS2; Growth-Arrest-Specific Protein 2 Domain
    smart00150
    Location:6909 → 7030
    SPEC; Spectrin repeats
    PHA03307
    Location:7266 → 7432
    PHA03307; transcriptional regulator ICP4; Provisional
    COG0419
    Location:3321 → 3890
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:4838 → 5131
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG3096
    Location:4595 → 4810
    MukB; Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Escherichia coli str. K-12 substr. MG1655 [Cell cycle control, cell division, chromosome partitioning]
    cd00051
    Location:7064 → 7126
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00176
    Location:6687 → 6899
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:1790 → 1829
    Plectin; Plectin repeat
    pfam17902
    Location:881 → 947
    SH3_10; SH3 domain
    pfam18373
    Location:982 → 1061
    Spectrin_like; Spectrin like domain
    cd21188
    Location:71 → 209
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:220 → 326
    CH_SF; calponin homology (CH) domain superfamily
    cl02488
    Location:3410 → 3652
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  21. XM_012957427.3 → XP_012812881.2  microtubule-actin cross-linking factor 1 isoform X9

    UniProtKB/TrEMBL
    A0A6I8QG99, A0A8J0SDG5
    Related
    ENSXETP00000071844.2, ENSXETT00000086213.2
    Conserved Domains (13) summary
    smart00243
    Location:7103 → 7178
    GAS2; Growth-Arrest-Specific Protein 2 Domain
    smart00150
    Location:6873 → 6994
    SPEC; Spectrin repeats
    PHA03307
    Location:7253 → 7419
    PHA03307; transcriptional regulator ICP4; Provisional
    COG0419
    Location:3285 → 3854
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:4802 → 5095
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    COG3096
    Location:4559 → 4774
    MukB; Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Escherichia coli str. K-12 substr. MG1655 [Cell cycle control, cell division, chromosome partitioning]
    cd00051
    Location:7028 → 7090
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00176
    Location:6651 → 6863
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:1754 → 1793
    Plectin; Plectin repeat
    pfam17902
    Location:845 → 911
    SH3_10; SH3 domain
    pfam18373
    Location:946 → 1025
    Spectrin_like; Spectrin like domain
    cl00030
    Location:21 → 182
    CH_SF; calponin homology (CH) domain superfamily
    cl02488
    Location:3374 → 3616
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  22. XM_012957429.3 → XP_012812883.2  microtubule-actin cross-linking factor 1 isoform X11

    UniProtKB/TrEMBL
    A0A6I8QG99, A0A8J0S871
    Conserved Domains (13) summary
    smart00243
    Location:7089 → 7164
    GAS2; Growth-Arrest-Specific Protein 2 Domain
    smart00150
    Location:6859 → 6980
    SPEC; Spectrin repeats
    PHA03307
    Location:7239 → 7405
    PHA03307; transcriptional regulator ICP4; Provisional
    COG0419
    Location:3271 → 3840
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:4117 → 4910
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00051
    Location:7014 → 7076
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00176
    Location:6637 → 6849
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:1740 → 1779
    Plectin; Plectin repeat
    pfam17902
    Location:831 → 897
    SH3_10; SH3 domain
    pfam18373
    Location:932 → 1011
    Spectrin_like; Spectrin like domain
    cd21188
    Location:21 → 159
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:170 → 276
    CH_SF; calponin homology (CH) domain superfamily
    cl02488
    Location:3360 → 3602
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  23. XM_012957423.3 → XP_012812877.2  microtubule-actin cross-linking factor 1 isoform X4

    UniProtKB/TrEMBL
    A0A6I8QG99, A0A8J0SFA4
    Conserved Domains (13) summary
    smart00243
    Location:7124 → 7199
    GAS2; Growth-Arrest-Specific Protein 2 Domain
    smart00150
    Location:6894 → 7015
    SPEC; Spectrin repeats
    PHA03307
    Location:7274 → 7440
    PHA03307; transcriptional regulator ICP4; Provisional
    COG1196
    Location:4152 → 4945
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00051
    Location:7049 → 7111
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00176
    Location:6672 → 6884
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    TIGR02168
    Location:3306 → 3954
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam00681
    Location:1775 → 1814
    Plectin; Plectin repeat
    pfam17902
    Location:866 → 932
    SH3_10; SH3 domain
    pfam18373
    Location:967 → 1046
    Spectrin_like; Spectrin like domain
    cd21188
    Location:56 → 194
    CH_PLEC-like_rpt1; first calponin homology (CH) domain found in the plectin/dystonin/MACF1 family
    cl00030
    Location:205 → 311
    CH_SF; calponin homology (CH) domain superfamily
    cl02488
    Location:3395 → 3637
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

  24. XM_012957430.3 → XP_012812884.2  microtubule-actin cross-linking factor 1 isoform X17

    UniProtKB/TrEMBL
    A0A8J0SGD7
    Conserved Domains (9) summary
    smart00243
    Location:5562 → 5637
    GAS2; Growth-Arrest-Specific Protein 2 Domain
    smart00150
    Location:5332 → 5453
    SPEC; Spectrin repeats
    PHA03307
    Location:5712 → 5878
    PHA03307; transcriptional regulator ICP4; Provisional
    COG0419
    Location:1743 → 2313
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    COG1196
    Location:2590 → 3383
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00051
    Location:5487 → 5549
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd00176
    Location:5110 → 5322
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam00681
    Location:213 → 252
    Plectin; Plectin repeat
    cl02488
    Location:1833 → 2075
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
Nucleotide Protein Strain
Heading Accession and Version

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