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ABI1 abl interactor 1 [ Homo sapiens (human) ]

Gene ID: 10006, updated on 14-Nov-2024

Summary

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Official Symbol
ABI1provided by HGNC
Official Full Name
abl interactor 1provided by HGNC
Primary source
HGNC:HGNC:11320
See related
Ensembl:ENSG00000136754 MIM:603050; AllianceGenome:HGNC:11320
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
E3B1; ABI-1; ABLBP4; NAP1BP; SSH3BP; SSH3BP1
Summary
This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Sep 2011]
Expression
Ubiquitous expression in bone marrow (RPKM 23.2), esophagus (RPKM 19.6) and 25 other tissues See more
Orthologs
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Genomic context

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See ABI1 in Genome Data Viewer
Location:
10p12.1
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (26746596..26860958, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (26768504..26882882, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (27035525..27149887, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene selenoprotein O like, pseudogene Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:26986797-26987685 Neighboring gene decaprenyl diphosphate synthase subunit 1 Neighboring gene heat shock protein family A (Hsp70) member 8 pseudogene 3 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3171 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3172 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3173 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3174 Neighboring gene H3K27ac hESC enhancer GRCh37_chr10:27070945-27071686 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3175 Neighboring gene small nucleolar RNA SNORA57 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2239 Neighboring gene RNA, U6 small nuclear 946, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2240 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2241 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2242 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3176 Neighboring gene small nucleolar RNA U13 Neighboring gene uncharacterized LOC124902398

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Adaptor protein Abelson interactor 1 in homeostasis and disease.
    Title: Adaptor protein Abelson interactor 1 in homeostasis and disease.
  2. Circulating miR-30e-3p induces disruption of neurite development in SH-SY5Y cells by targeting ABI1, a novel biomarker for schizophrenia.
    Title: Circulating miR-30e-3p induces disruption of neurite development in SH-SY5Y cells by targeting ABI1, a novel biomarker for schizophrenia.
  3. Pan-cancer transcriptomic data of ABI1 transcript variants and molecular constitutive elements identifies novel cancer metastatic and prognostic biomarkers.
    Title: Pan-cancer transcriptomic data of ABI1 transcript variants and molecular constitutive elements identifies novel cancer metastatic and prognostic biomarkers.
  4. ABI1-based expression signature predicts breast cancer metastasis and survival.
    Title: ABI1-based expression signature predicts breast cancer metastasis and survival.
  5. The roles and prognostic significance of ABI1-TSV-11 expression in patients with left-sided colorectal cancer.
    Title: The roles and prognostic significance of ABI1-TSV-11 expression in patients with left-sided colorectal cancer.
  6. Acetylation of Abelson interactor 1 at K416 regulates actin cytoskeleton and smooth muscle contraction.
    Title: Acetylation of Abelson interactor 1 at K416 regulates actin cytoskeleton and smooth muscle contraction.
  7. RNA Splicing of the Abi1 Gene by MBNL1 contributes to macrophage-like phenotype modulation of vascular smooth muscle cell during atherogenesis.
    Title: RNA Splicing of the Abi1 Gene by MBNL1 contributes to macrophage-like phenotype modulation of vascular smooth muscle cell during atherogenesis.
  8. PTEN dephosphorylates Abi1 to promote epithelial morphogenesis.
    Title: PTEN dephosphorylates Abi1 to promote epithelial morphogenesis.
  9. PTEN suppresses epithelial-mesenchymal transition and cancer stem cell activity by downregulating Abi1.
    Title: PTEN suppresses epithelial-mesenchymal transition and cancer stem cell activity by downregulating Abi1.
  10. Distinctive roles of Abi1 in regulating actin-associated proteins during human smooth muscle cell migration.
    Title: Distinctive roles of Abi1 in regulating actin-associated proteins during human smooth muscle cell migration.
Submit: New GeneRIF Correction See all GeneRIFs (53)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables SH3 domain binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables cadherin binding HDA PubMed 
enables cytoskeletal protein binding TAS
Traceable Author Statement
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein tyrosine kinase activator activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables signaling adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables signaling adaptor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables signaling adaptor activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in actin polymerization or depolymerization NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in cell projection morphogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell surface receptor protein tyrosine kinase signaling pathway TAS
Traceable Author Statement
more info
 PubMed 
involved_in dendrite morphogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in lamellipodium morphogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in megakaryocyte development IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of cell population proliferation TAS
Traceable Author Statement
more info
 PubMed 
involved_in neuron migration IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within positive regulation of protein tyrosine kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in somitogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of SCAR complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of SCAR complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in actin-based cell projection IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol TAS
Traceable Author Statement
more info
  
located_in endoplasmic reticulum TAS
Traceable Author Statement
more info
 PubMed 
located_in extracellular exosome HDA PubMed 
located_in filopodium tip IDA
Inferred from Direct Assay
more info
 PubMed 
located_in growth cone IEA
Inferred from Electronic Annotation
more info
  
is_active_in lamellipodium IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in lamellipodium IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in postsynaptic density IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
abl interactor 1
Names
Abelson interactor 1
Abl-interactor protein 1 long
abl-binding protein 4
eps8 SH3 domain-binding protein
interactor protein AblBP4
nap1 binding protein
spectrin SH3 domain-binding protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_030025.1 RefSeqGene

    Range
    5130..119492
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001012750.3 → NP_001012768.1  abl interactor 1 isoform b

    See identical proteins and their annotated locations for NP_001012768.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame coding exon, compared to variant 1. The resulting protein (isoform b) has the same N- and C-termini but is shorter compared to isoform a.
    Source sequence(s)
    AB040151, AF006516, AL390961
    Consensus CDS
    CCDS31171.1
    UniProtKB/TrEMBL
    Q59G41
    Related
    ENSP00000365310.3, ENST00000376140.4
    Conserved Domains (2) summary
    cd11971
    Location:423 → 481
    SH3_Abi1; Src homology 3 domain of Abl Interactor 1
    pfam07815
    Location:93 → 156
    Abi_HHR; Abl-interactor HHR

  2. NM_001012751.3 → NP_001012769.1  abl interactor 1 isoform c

    See identical proteins and their annotated locations for NP_001012769.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) lacks two alternate in-frame coding exons, compared to variant 1. The resulting protein (isoform c) has the same N- and C-termini but is shorter compared to isoform a.
    Source sequence(s)
    AB040151, AL390961
    Consensus CDS
    CCDS31170.1
    UniProtKB/TrEMBL
    Q59G41
    Related
    ENSP00000365308.3, ENST00000376138.7
    Conserved Domains (2) summary
    cd11971
    Location:394 → 452
    SH3_Abi1; Src homology 3 domain of Abl Interactor 1
    pfam07815
    Location:93 → 156
    Abi_HHR; Abl-interactor HHR

  3. NM_001012752.3 → NP_001012770.1  abl interactor 1 isoform d

    See identical proteins and their annotated locations for NP_001012770.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) lacks two alternate in-frame coding exons, compared to variant 1. The resulting protein (isoform d) has the same N- and C-termini but is shorter compared to isoform a.
    Source sequence(s)
    AB040151, AL390961, BC024254
    Consensus CDS
    CCDS31169.1
    UniProtKB/TrEMBL
    Q59G41
    Related
    ENSP00000365309.2, ENST00000376139.6
    Conserved Domains (2) summary
    cd11971
    Location:418 → 476
    SH3_Abi1; Src homology 3 domain of Abl Interactor 1
    pfam07815
    Location:93 → 154
    Abi_HHR; Abl-interactor HHR

  4. NM_001178116.2 → NP_001171587.1  abl interactor 1 isoform e

    See identical proteins and their annotated locations for NP_001171587.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) contains one alternate exon and lacks a different in-frame coding exon, compared to variant 1. The resulting protein (isoform e) has the same N- and C-termini but is shorter when it is compared to isoform a.
    Source sequence(s)
    AK126803, AL390961
    Consensus CDS
    CCDS53501.1
    UniProtKB/TrEMBL
    Q59G41
    Related
    ENSP00000279599.8, ENST00000346832.10
    Conserved Domains (2) summary
    cd11971
    Location:438 → 496
    SH3_Abi1; Src homology 3 domain of Abl Interactor 1
    pfam07815
    Location:110 → 186
    Abi_HHR; Abl-interactor HHR

  5. NM_001178119.2 → NP_001171590.1  abl interactor 1 isoform f

    See identical proteins and their annotated locations for NP_001171590.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) lacks an alternate in-frame coding exon and uses a different splice site, compared to variant 1. The resulting protein (isoform f) has the same N- and C-termini but is shorter when it is compared to isoform a.
    Source sequence(s)
    AB040151, AF006516, AL390961
    Consensus CDS
    CCDS53500.1
    UniProtKB/TrEMBL
    Q59G41
    Related
    ENSP00000352114.4, ENST00000359188.8
    Conserved Domains (2) summary
    cd11971
    Location:422 → 480
    SH3_Abi1; Src homology 3 domain of Abl Interactor 1
    pfam07815
    Location:93 → 156
    Abi_HHR; Abl-interactor HHR

  6. NM_001178120.2 → NP_001171591.1  abl interactor 1 isoform g

    See identical proteins and their annotated locations for NP_001171591.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) lacks two alternate in-frame coding exons and uses a different splice site, compared to variant 1. The resulting protein (isoform g) has the same N- and C-termini but is shorter when it is compared to isoform a.
    Source sequence(s)
    AB040151, AF001628, AL390961
    Consensus CDS
    CCDS53499.1
    UniProtKB/TrEMBL
    Q59G41
    Related
    ENSP00000365340.4, ENST00000376170.8
    Conserved Domains (2) summary
    cd11971
    Location:393 → 451
    SH3_Abi1; Src homology 3 domain of Abl Interactor 1
    pfam07815
    Location:93 → 156
    Abi_HHR; Abl-interactor HHR

  7. NM_001178121.2 → NP_001171592.1  abl interactor 1 isoform h

    See identical proteins and their annotated locations for NP_001171592.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) lacks three alternate in-frame coding exons and uses a different splice site, compared to variant 1. The resulting protein (isoform h) has the same N- and C-termini but is shorter when it is compared to isoform a. This isoform has also been called the 'long' isoform.
    Source sequence(s)
    AB040151, AF260262, AK291823, AL390961
    Consensus CDS
    CCDS53498.1
    UniProtKB/TrEMBL
    Q59G41
    Related
    ENSP00000365336.1, ENST00000376166.5
    Conserved Domains (2) summary
    cd11971
    Location:388 → 446
    SH3_Abi1; Src homology 3 domain of Abl Interactor 1
    pfam07815
    Location:93 → 154
    Abi_HHR; Abl-interactor HHR

  8. NM_001178122.2 → NP_001171593.1  abl interactor 1 isoform i

    See identical proteins and their annotated locations for NP_001171593.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) lacks two alternate in-frame coding exons, compared to variant 1. The resulting protein (isoform i) has the same N- and C-termini but is shorter when it is compared to isoform a. This isoform has also been called 'variant 41'.
    Source sequence(s)
    AB040151, AL390961, FJ380057
    Consensus CDS
    CCDS73078.1
    UniProtKB/TrEMBL
    B6VEX3, B6VEX5
    Related
    ENSP00000365307.5, ENST00000376137.9
    Conserved Domains (2) summary
    cd11971
    Location:364 → 422
    SH3_Abi1; Src homology 3 domain of Abl Interactor 1
    pfam07815
    Location:93 → 156
    Abi_HHR; Abl-interactor HHR

  9. NM_001178123.2 → NP_001171594.1  abl interactor 1 isoform j

    See identical proteins and their annotated locations for NP_001171594.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10) lacks three alternate in-frame coding exons, compared to variant 1. The resulting protein (isoform j) has the same N- and C-termini but is shorter when it is compared to isoform a. This isoform has also been called 'variant 21'.
    Source sequence(s)
    AB040151, AL390961, FJ380058
    Consensus CDS
    CCDS73077.1
    UniProtKB/TrEMBL
    B6VEX4, B6VEX5, F5H1G9
    Related
    ENSP00000439646.2, ENST00000536334.5
    Conserved Domains (2) summary
    cd11971
    Location:335 → 393
    SH3_Abi1; Src homology 3 domain of Abl Interactor 1
    pfam07815
    Location:93 → 156
    Abi_HHR; Abl-interactor HHR

  10. NM_001178124.2 → NP_001171595.1  abl interactor 1 isoform k

    See identical proteins and their annotated locations for NP_001171595.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11) lacks three alternate in-frame coding exons, compared to variant 1. The resulting protein (isoform k) has the same N- and C-termini but is shorter when it is compared to isoform a. This isoform has also been called 'variant 72'.
    Source sequence(s)
    AB040151, AL390961, FJ380059
    UniProtKB/TrEMBL
    B6VEX5
    Conserved Domains (2) summary
    cd11971
    Location:330 → 388
    SH3_Abi1; Src homology 3 domain of Abl Interactor 1
    pfam07815
    Location:93 → 154
    Abi_HHR; Abl-interactor HHR

  11. NM_001178125.2 → NP_001171596.1  abl interactor 1 isoform l

    See identical proteins and their annotated locations for NP_001171596.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (12) lacks five alternate in-frame coding exons, compared to variant 1. The resulting protein (isoform l) has the same N- and C-termini but is shorter when it is compared to isoform a.
    Source sequence(s)
    AK298646, AL390961
    Consensus CDS
    CCDS53497.1
    UniProtKB/TrEMBL
    B6VEX5
    Related
    ENSP00000440101.1, ENST00000490841.7
    Conserved Domains (1) summary
    cd11971
    Location:271 → 329
    SH3_Abi1; Src homology 3 domain of Abl Interactor 1

  12. NM_001348029.2 → NP_001334958.1  abl interactor 1 isoform m

    Status: REVIEWED

    Source sequence(s)
    AL139404, AL390961
    UniProtKB/TrEMBL
    Q59G41
    Conserved Domains (2) summary
    cd11971
    Location:449 → 507
    SH3_Abi1; Src homology 3 domain of Abl Interactor 1
    pfam07815
    Location:93 → 156
    Abi_HHR; Abl-interactor HHR

  13. NM_001348030.2 → NP_001334959.1  abl interactor 1 isoform n

    Status: REVIEWED

    Source sequence(s)
    AL139404, AL390961
    UniProtKB/TrEMBL
    Q59G41
    Conserved Domains (2) summary
    cd11971
    Location:389 → 447
    SH3_Abi1; Src homology 3 domain of Abl Interactor 1
    pfam07815
    Location:93 → 154
    Abi_HHR; Abl-interactor HHR

  14. NM_001348031.2 → NP_001334960.1  abl interactor 1 isoform o

    Status: REVIEWED

    Source sequence(s)
    AL139404, AL390961
    UniProtKB/TrEMBL
    B6VEX5
    Conserved Domains (2) summary
    cd11971
    Location:362 → 420
    SH3_Abi1; Src homology 3 domain of Abl Interactor 1
    pfam07815
    Location:93 → 156
    Abi_HHR; Abl-interactor HHR

  15. NM_001348032.2 → NP_001334961.1  abl interactor 1 isoform p

    Status: REVIEWED

    Source sequence(s)
    AL139404, AL390961
    UniProtKB/TrEMBL
    Q59G41
    Conserved Domains (2) summary
    cd11971
    Location:421 → 479
    SH3_Abi1; Src homology 3 domain of Abl Interactor 1
    pfam07815
    Location:93 → 156
    Abi_HHR; Abl-interactor HHR

  16. NM_001348033.2 → NP_001334962.1  abl interactor 1 isoform q

    Status: REVIEWED

    Source sequence(s)
    AL139404, AL390961
    UniProtKB/TrEMBL
    Q59G41
    Conserved Domains (2) summary
    cd11971
    Location:420 → 478
    SH3_Abi1; Src homology 3 domain of Abl Interactor 1
    pfam07815
    Location:93 → 156
    Abi_HHR; Abl-interactor HHR

  17. NM_001348034.2 → NP_001334963.1  abl interactor 1 isoform r

    Status: REVIEWED

    Source sequence(s)
    AL139404, AL390961
    UniProtKB/TrEMBL
    B6VEX5
    Conserved Domains (2) summary
    cd11971
    Location:391 → 449
    SH3_Abi1; Src homology 3 domain of Abl Interactor 1
    pfam07815
    Location:93 → 169
    Abi_HHR; Abl-interactor HHR

  18. NM_001410909.1 → NP_001397838.1  abl interactor 1 isoform s

    Status: REVIEWED

    Source sequence(s)
    AL139404, AL390961
    Consensus CDS
    CCDS91224.1
    UniProtKB/TrEMBL
    A0A0A0MRT6
    Related
    ENSP00000365330.1, ENST00000376160.5

  19. NM_005470.4 → NP_005461.2  abl interactor 1 isoform a

    See identical proteins and their annotated locations for NP_005461.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform a).
    Source sequence(s)
    AB040151, AL390961, U87166
    Consensus CDS
    CCDS7150.1
    UniProtKB/Swiss-Prot
    A9Z1Y6, B3KX62, B4DQ58, H7BXI6, O15147, O76049, O95060, Q5T2R3, Q5T2R4, Q5T2R6, Q5T2R7, Q5T2R9, Q5W070, Q5W072, Q8IZP0, Q8TB63, Q96S81, Q9NXZ9, Q9NYB8
    UniProtKB/TrEMBL
    Q59G41
    Related
    ENSP00000365312.2, ENST00000376142.6
    Conserved Domains (2) summary
    cd11971
    Location:450 → 508
    SH3_Abi1; Src homology 3 domain of Abl Interactor 1
    pfam07815
    Location:93 → 156
    Abi_HHR; Abl-interactor HHR

RNA

  1. NR_145410.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AL139404, AL390961

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    26746596..26860958 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047424407.1 → XP_047280363.1  abl interactor 1 isoform X5

  2. XM_047424406.1 → XP_047280362.1  abl interactor 1 isoform X4

  3. XM_047424404.1 → XP_047280360.1  abl interactor 1 isoform X2

  4. XM_047424405.1 → XP_047280361.1  abl interactor 1 isoform X3

  5. XM_005252332.5 → XP_005252389.1  abl interactor 1 isoform X1

    See identical proteins and their annotated locations for XP_005252389.1

    UniProtKB/TrEMBL
    Q59G41
    Conserved Domains (2) summary
    cd11971
    Location:445 → 503
    SH3_Abi1; Src homology 3 domain of Abl Interactor 1
    pfam07815
    Location:93 → 154
    Abi_HHR; Abl-interactor HHR

  6. XM_047424409.1 → XP_047280365.1  abl interactor 1 isoform X9

  7. XM_011519289.3 → XP_011517591.1  abl interactor 1 isoform X6

    Conserved Domains (1) summary
    pfam07815
    Location:93 → 169
    Abi_HHR; Abl-interactor HHR

  8. XM_047424408.1 → XP_047280364.1  abl interactor 1 isoform X8

  9. XM_017015459.2 → XP_016870948.1  abl interactor 1 isoform X7

RNA

  1. XR_007061931.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    26768504..26882882 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054364459.1 → XP_054220434.1  abl interactor 1 isoform X5

  2. XM_054364458.1 → XP_054220433.1  abl interactor 1 isoform X4

  3. XM_054364456.1 → XP_054220431.1  abl interactor 1 isoform X2

  4. XM_054364457.1 → XP_054220432.1  abl interactor 1 isoform X3

  5. XM_054364455.1 → XP_054220430.1  abl interactor 1 isoform X1

  6. XM_054364460.1 → XP_054220435.1  abl interactor 1 isoform X6

  7. XM_054364463.1 → XP_054220438.1  abl interactor 1 isoform X9

  8. XM_054364462.1 → XP_054220437.1  abl interactor 1 isoform X8

  9. XM_054364461.1 → XP_054220436.1  abl interactor 1 isoform X7

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8IZP0.4 GenPept UniProtKB/Swiss-Prot:Q8IZP0

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