trhde.1 thyrotropin releasing hormone degrading enzyme, tandem duplicate 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: trhde.1provided by ZNC
Official Full Name: thyrotropin releasing hormone degrading enzyme, tandem duplicate 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-170406-2
See related: Ensembl:ENSDARG00000109358 AllianceGenome:ZFIN:ZDB-GENE-170406-2
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: PAP-II; trh-de; trhde1-1; si:ch211-149p5.1
Summary: Orthologous to human TRHDE (thyrotropin releasing hormone degrading enzyme). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 4

Exon count:: 19

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	4	NC_007115.7 (23223789..23409301)
105	previous assembly	GRCz10 (GCF_000002035.5)	4	NC_007115.6 (23502527..23691113)

Chromosome 4 - NC_007115.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

General protein information

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Preferred Names: thyrotropin releasing hormone degrading enzyme, tandem duplicate 1; thyrotropin-releasing hormone-degrading ectoenzyme

Names: TRH-degrading ectoenzyme); pyroglutamyl-peptidase II

XP_001345457.3

EC 3.4.11.-

XP_021329677.1

EC 3.4.11.-

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007115.7 Reference GRCz11 Primary Assembly

Range

23223789..23409301

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_001345421.8 → XP_001345457.3 thyrotropin-releasing hormone-degrading ectoenzyme isoform X1

UniProtKB/TrEMBL

A0A8M1Q7Z4

Related

ENSDARP00000083559.5, ENSDART00000089126.7

Conserved Domains (3) summary

cd09601
Location:118 → 568

M1_APN_2; Peptidase M1 Aminopeptidase N family incudes tricorn interacting factor F3, Endoplasmic reticulum aminopeptidase 1 (ERAP1), Aminopeptidase Q (APQ)

pfam01433
Location:109 → 500

Peptidase_M1; Peptidase family M1

pfam11838
Location:649 → 968

ERAP1_C; ERAP1-like C-terminal domain

Reference GRCz11 ALT_DRER_TU_2

Genomic

NW_018395231.1 Reference GRCz11 ALT_DRER_TU_2

Range

400834..480940

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021474002.2 → XP_021329677.1 thyrotropin-releasing hormone-degrading ectoenzyme isoform X2

UniProtKB/TrEMBL

A0A8M9PET6

Conserved Domains (1) summary

cd09601
Location:118 → 415

M1_APN_2; Peptidase M1 Aminopeptidase N family incudes tricorn interacting factor F3, Endoplasmic reticulum aminopeptidase 1 (ERAP1), Aminopeptidase Q (APQ)