GEO DataSets

(Submitter supplied) ChIP-chip to determine the regulation of the K. lactis hsgs (ChIP of MATa1, MATalpha2, and RME1). The MATa1 and MATalpha2 ChIPs were performed in an a/alpha cell using N-terminally HA-tagged proteins and the RME1 ChIPs were perfomed in an a cell using C-terminally myc-tagged protein. For the RME1 ChIPs, the cells grown with out phosphate. For the MATa1 andMATalpha2 ChIPs the cells were grown in YEPD.

Organism:

Kluyveromyces lactis; Kluyveromyces lactis NRRL Y-1140

Type:

Genome binding/occupancy profiling by genome tiling array

Platform:

GPL11182

6 Samples

Download data: GPR

(Submitter supplied) WT and rme1 KO K. lactis cells (a, alpha, and a/alpha) were grown in YEPD, phosphate starvation and phosphate starvation with the addition of alpha pheromone. The goal was to identify cell-type regulated genes and to determine the effects of growth media on the regulation of cell-type regulated genes

Organism:

Kluyveromyces lactis

Type:

Expression profiling by array

Platform:

GPL10962

20 Samples

Download data: GPR

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Lachancea kluyveri

Type:

Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platform:

GPL32984

25 Samples

Download data: BW

(Submitter supplied) Over evolutionary timescales, the logic and pattern of cell-type specific gene expression can remain constant, yet the molecular mechanisms underlying such regulation can drift between alternative forms. Here, we document a new, especially clear example of this principle in the regulation of the haploid-specific genes across a wide group of fungal species. For most species, transcription of these genes is repressed in the a/ a cell type by a heterodimer of two homeodomain proteins, Mata1 and Mata2. more...

Organism:

Lachancea kluyveri

Type:

Expression profiling by high throughput sequencing

Platform:

GPL32984

9 Samples

Download data: CSV, TXT

(Submitter supplied) Over evolutionary timescales, the logic and pattern of cell-type specific gene expression can remain constant, yet the molecular mechanisms underlying such regulation can drift between alternative forms. Here, we document a new, especially clear example of this principle in the regulation of the haploid-specific genes across a wide group of fungal species. For most species, transcription of these genes is repressed in the a/ a cell type by a heterodimer of two homeodomain proteins, Mata1 and Mata2. more...

Organism:

Lachancea kluyveri

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platform:

GPL32984

16 Samples

Download data: BW

(Submitter supplied) The human commensal and opportunistic pathogen Candida albicans can switch between two distinct, heritable cell types, named “white” and “opaque,” which differ in morphology, mating abilities, metabolic preferences, and in their interactions with the host immune system. Previous studies revealed a highly interconnected group of transcriptional regulators that control switching between the two cell types. more...

Organism:

Candida albicans

Type:

Expression profiling by array

Platform:

GPL13830

21 Samples

Download data: GPR

(Submitter supplied) The human fungal pathogen Candida albicans can switch between two phenotypic cell types, termed “white” and “opaque.” Both cell types are heritable for many generations, and the switch between the two types occurs epigenetically, that is, without a change in the DNA sequence of the genome. In this work we describe that SSN6, the C. albicans functional homolog of Saccharomyces cerevisiae Cyc8, is a regulator of the white-opaque switch. more...

Organism:

Candida albicans

Type:

Genome binding/occupancy profiling by genome tiling array

Platform:

GPL16365

9 Samples

Download data: GPR

(Submitter supplied) The purpose of this experiment was to determine the genes directly regulated by Ste12 in K. lactis. The experiment was performed in a cells to determine if the a-specific genes were bound by Ste12. Ste12 was tagged with c-myc and was immunoprecipitated with a c-myc antibody. Cells were starved in SD media lacking phosphate for 2 hours, then treated with 10µg/mL K. lactis alpha factor for 2 hours before harvesting. more...

Organism:

Kluyveromyces lactis

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platform:

GPL19759

4 Samples

Download data: BEDGRAPH

(Submitter supplied) A fundamental problem in biology is the molecular basis for divergence among related organisms. We have investigated the level of divergence of transcription factor binding sites for two key factors that regulate developmental processes in the budding yeasts. The genomic binding locations for the Ste12 and Tec1 transcription factors in S. cerevisiae, S. mikatae and S. bayanus were mapped by chromatin immunoprecipitation combined with microarrays (chIP chip)1, 2 and compared to one another. more...

Organism:

Candida albicans; Saccharomyces mikatae; Saccharomyces bayanus; Saccharomyces cerevisiae

Type:

Genome binding/occupancy profiling by genome tiling array

4 related Platforms

27 Samples

Download data

(Submitter supplied) Coordinated ribosomal protein (RP) gene expression is crucial for cellular viability, but the transcriptional network controlling this regulon has only been well characterized in the yeast Saccharomyces cerevisiae. We have used whole-genome transcriptional and location profiling to establish that, in Candida albicans, the RP regulon is controlled by the Myb-domain protein Tbf1 working in conjunction with Cbf1. more...

Organism:

Candida albicans

Type:

Expression profiling by array; Genome binding/occupancy profiling by genome tiling array

Platforms:

GPL6475 GPL6474

16 Samples

Download data: TXT

(Submitter supplied) Coordinated ribosomal protein (RP) gene expression is crucial for cellular viability, but the transcriptional network controlling this regulon has only been well characterized in the yeast Saccharomyces cerevisiae. We have used whole-genome transcriptional and location profiling to establish that, in Candida albicans, the RP regulon is controlled by the Myb-domain protein Tbf1 working in conjunction with Cbf1. more...

Organism:

Candida albicans

Type:

Expression profiling by array

Platform:

GPL6475

12 Samples

Download data: TXT

(Submitter supplied) Coordinated ribosomal protein (RP) gene expression is crucial for cellular viability, but the transcriptional network controlling this regulon has only been well characterized in the yeast Saccharomyces cerevisiae. We have used whole-genome transcriptional and location profiling to establish that, in Candida albicans, the RP regulon is controlled by the Myb-domain protein Tbf1 working in conjunction with Cbf1. more...

Organism:

Candida albicans

Type:

Genome binding/occupancy profiling by genome tiling array

Platform:

GPL6474

4 Samples

Download data: TXT

(Submitter supplied) The Regulation of Ace2 and Morphogenesis (RAM) pathway is an important regulatory network in the human fungal pathogen Candida albicans. The RAM pathway’s two most well-studied components, the NDR/Lats kinase Cbk1 and its putative substrate, the transcription factor Ace2, have a wide range of phenotypes and functions. It is not clear, however, which of these functions are specifically due to the phosphorylation of Ace2 by Cbk1. more...

Organism:

Candida albicans

Type:

Expression profiling by high throughput sequencing

Platform:

GPL28323

18 Samples

Download data: CSV, XLSX

(Submitter supplied) Rme1, a conserved transcription factor among members of the ascomycete lineage, regulates meiosis and pseudohyphal growth in baker’s yeast. The genome of the meiosis-defective fungal pathogen Candida albicans encodes a Rme1 homolog, which we previously mapped within a transcriptional circuitry that controls hyphal growth. To delineate a possible role of Rme1 in C. albicans morphogenesis, we combined genome-wide expression and location analyses of Rme1. more...

Organism:

Candida albicans

Type:

Expression profiling by array

Platform:

GPL19932

9 Samples

Download data: GPR

(Submitter supplied) Rme1, a conserved transcription factor among members of the ascomycete lineage, regulates meiosis and pseudohyphal growth in baker’s yeast. The genome of the meiosis-defective fungal pathogen Candida albicans encodes a Rme1 homolog, which we previously mapped within a transcriptional circuitry that controls hyphal growth. To delineate a possible role of Rme1 in C. albicans morphogenesis, we combined genome-wide expression and location analyses of Rme1. more...

Organism:

Candida albicans

Type:

Genome binding/occupancy profiling by genome tiling array

Platform:

GPL17892

2 Samples

Download data: GPR

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Clavispora lusitaniae; Clavispora lusitaniae ATCC 42720

Type:

Expression profiling by array

Platform:

GPL17847

70 Samples

Download data: GPR

(Submitter supplied) Transcriptional profiling of C. lusitaniae a/alpha WT cells on 0.37% PDA (potato dextrose agar) for 30 minutes (m), 2 hours (h), 4h, 8h, 12h, 18h, 24, and 30h hybridized against WT a/alpha cells in non-meiosis inducing conditions YPD (yeast peptone dextrose) for 2h

Organism:

Clavispora lusitaniae; Clavispora lusitaniae ATCC 42720

Type:

Expression profiling by array

Platform:

GPL17847

32 Samples

Download data: GPR

(Submitter supplied) Transcriptional profiling of C. lusitaniae a/alpha ste12Δ/ste12Δ deletion mutants on .37% PDA (potato dextrose agar) media for 0 hours (h), 12h, 28h, and 24 hours hybridized against WT a/alpha cells on YPD (yeast peptone dextrose) media for 2h

Organism:

Clavispora lusitaniae ATCC 42720; Clavispora lusitaniae

Type:

Expression profiling by array

Platform:

GPL17847

4 Samples

Download data: GPR

(Submitter supplied) Transcriptional profiling of C. lusitaniae WT a and WT alpha cells on 0.37% PDA (potato dextrose agar) for 30 minutes (m), 2 hours (h), or 24h hybridized against WT a and WT alpha cells in YPD (yeast peptone dextrose) for 2h

Organism:

Clavispora lusitaniae; Clavispora lusitaniae ATCC 42720

Type:

Expression profiling by array

Platform:

GPL17847

10 Samples

Download data: GPR

(Submitter supplied) Transcriptional profiling of C. lusitaniae ime2Δ/ime2Δ a/alpha WT cells on 0.37% PDA (potato dextrose agar) for 0 hours, 12h, 18h and 24h hybridized against WT a/alpha cells in YPD (yeast peptone dextrose) for 4h

Organism:

Clavispora lusitaniae; Clavispora lusitaniae ATCC 42720

Type:

Expression profiling by array

Platform:

GPL17847

12 Samples

Download data: GPR