GEO DataSets

(Submitter supplied) The transcription factor KlPdr1p, belonging to the Zn2Cys6 family, is a central regulator of efflux pump expression in Kluyveromyces lactis. To better understand how KlPDR1-mediated drug resistance is achieved in K. lactis, we used DNA microarrays to identify genes whose expression was affected by deletion or overexpression of the KlPDR1 gene. All microarray experiments were performed using the 30K Kluyveromyces lactis NRRL Y-1140 microarray (MYcroarray, 5692 Plymouth Road, Ann Arbor, MI 48105, USA). more...

Organism:

Kluyveromyces lactis NRRL Y-1140; Kluyveromyces lactis

Type:

Expression profiling by array

Platform:

GPL21259

2 Samples

Download data: GPR

(Submitter supplied) We examine how different transcriptional network structures can evolve from an ancestral network. We show that regulatory protein modularity, conversion of one cis-regulatory sequence to another, distribution of binding energy among protein-protein and protein-DNA interactions, and exploitation of ancestral network features all contribute to the evolution of a novel mode of regulation at a conserved gene set. more...

Organism:

Kluyveromyces lactis NRRL Y-1140; Kluyveromyces lactis

Type:

Genome binding/occupancy profiling by genome tiling array

Platform:

GPL11182

6 Samples

Download data: GPR

(Submitter supplied) ChIP-chip to determine the regulation of the K. lactis hsgs (ChIP of MATa1, MATalpha2, and RME1). The MATa1 and MATalpha2 ChIPs were performed in an a/alpha cell using N-terminally HA-tagged proteins and the RME1 ChIPs were perfomed in an a cell using C-terminally myc-tagged protein. For the RME1 ChIPs, the cells grown with out phosphate. For the MATa1 andMATalpha2 ChIPs the cells were grown in YEPD.

Organism:

Kluyveromyces lactis; Kluyveromyces lactis NRRL Y-1140

Type:

Genome binding/occupancy profiling by genome tiling array

Platform:

GPL11182

6 Samples

Download data: GPR

(Submitter supplied) Kluyveromyces lactis NRRL Y-1140 has 5327 genes. The manufacturer used 15437 probes designed to survey 5260 genes (or 98.7% of all genes) for this organism. The Kluyveromyces lactis NRRL Y-1140 genome used for the probe design was provided in 6 pieces of sequence ( NC_006037, NC_006038, NC_006039, NC_006040, NC_006041, NC_006042 ) representing a total of 5327 transcripts. The the sequences were analyzed for their GC content as this is an important parameter for probe design. more...

Organism:

Kluyveromyces lactis NRRL Y-1140

1 Series

2 Samples

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(Submitter supplied) Design ID: 018173 GenBank accession numbers: NC_006037-0067042 GenBank release date: 07/2004 Downloaded: 05/2006 Protocol: see manufacturer's website

Organism:

Kluyveromyces lactis NRRL Y-1140

2 Series

12 Samples

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