GEO DataSets

(Submitter supplied) The RNA sequencing approach was utilized to carry out a comparative transcriptome analysis between Streptomyces hygroscopicus 5008 wild-type and a genetically engineered strain. The A-factor-like cascade play an important role in the regulation of validamycin biosynthesis by Streptomyces hygroscopicus 5008, and the pleiotropic regulator AdpA-H may positively regulate the transcription of gene cluster for the biosynthesis. more...

Organism:

Streptomyces hygroscopicus subsp. jinggangensis 5008

Type:

Expression profiling by high throughput sequencing

Platform:

GPL18744

2 Samples

Download data: TXT

(Submitter supplied) To explore the molecular basis of validamycin overproduction at the transcriptional level, the transcriptomes of strain 5008 and TL01 cultivated in Yeast extract-Malt extract-Glucose (YMG) and rice-peanut cake based industrial (IND) fermentation medium were compared by microarray analysis.

Organism:

Streptomyces hygroscopicus subsp. jinggangensis; Streptomyces hygroscopicus subsp. jinggangensis 5008; Streptomyces hygroscopicus subsp. jinggangensis TL01

Type:

Expression profiling by array

Platform:

GPL15794

16 Samples

Download data: TXT

(Submitter supplied) To explore the molecular mechanism of the positive thermoregulation on Jinggangmycin A biosynthesis, the transcriptomes of S. hygroscopicus 5008 cultivated at 30℃ or 37℃ in liquid medium were compared by microarray analysis.

Organism:

Streptomyces hygroscopicus subsp. jinggangensis; Streptomyces hygroscopicus subsp. jinggangensis 5008

Type:

Expression profiling by array

Platform:

GPL15170

8 Samples

Download data: TXT