ClinVar Genomic variation as it relates to human health
NM_198578.4(LRRK2):c.3487A>T (p.Asn1163Tyr)
Germline
Classification
(2)
Uncertain significance
criteria provided, multiple submitters, no conflicts
Somatic
No data submitted for somatic clinical impact
Somatic
No data submitted for oncogenicity
Genes
Gene | OMIM | ClinGen Gene Dosage Sensitivity Curation | Variation Viewer | Related variants | ||
---|---|---|---|---|---|---|
HI score | TS score | Within gene | All | |||
LRRK2 | - | - |
GRCh38 GRCh37 |
3552 | 3577 |
Conditions - Germline
Condition | Classification
(# of submissions) |
Review status | Last evaluated | Variation/condition record |
---|---|---|---|---|
Uncertain significance (1) |
|
Feb 28, 2024 | RCV004525191.1 | |
Uncertain significance (1) |
|
Jun 1, 2024 | RCV004585105.3 |
Citations for germline classification of this variant
HelpText-mined citations for this variant ...
HelpRecord last updated Oct 08, 2024