1EH9,3M07


Conserved Protein Domain Family
trehalose_TreZ

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TIGR02402: trehalose_TreZ 
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malto-oligosyltrehalose trehalohydrolase
Members of this family are the trehalose biosynthetic enzyme malto-oligosyltrehalose trehalohydrolase, formally known as 4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase (EC 3.2.1.141). It is the TreZ protein of the TreYZ pathway for trehalose biosynthesis, and alternative to the OtsAB system. [Energy metabolism, Biosynthesis and degradation of polysaccharides]
Statistics
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PSSM-Id: 274114
Aligned: 17 rows
Threshold Bit Score: 666.349
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1EH9_A        11 VIFTLWAPYQKSVK--LKVLEKgLYEMERDEK--GYFTITLNnVKVRDRYKYVLDD----ASEIPDPASRYQPEGVHGPS 82  Sulfolobus solf...
Q10769         2 PEFRVWAPKPALVR--LDVNGA-VHAMTRSAD--GWWHTTVAaPADA-RYGYLLDDd---PTVLPDPRSARQPDGVHARS 72  Mycobacterium t...
BAC18835      11 LKYRVWAPRPEDVR--LHLNGE-TLPMTRTDG--DWWVADREpAVGD-RYGFELFDgtewSKTVPDPRSQYQPDGVHGLS 84  Corynebacterium...
AAL20478      20 VRFRLWATGQQKVM--LRLAGK-DQEMQANGD--GWFTLDVAgVTPGTEYNFVLSDg----MVVPDPASRAQKTDVNGPS 90  Salmonella ente...
CAE33358      17 IRFRLWAPSAPPALalEIEGRA-PIALRPGPD--GYAQAIVD-GAPGLRYRYRLAAd----CAVPDPASRLQDGDVHGHS 88  Bordetella bron...
AAM35318      21 VRFALWAPEAKNVDv-VFANGA-RSALQAGQD--GFFSALID-CAADARYRYSVDGg----ePVPDPASRWQPEGVHGPS 91  Xanthomonas axo...
CAD17388      28 TRFRLWAPDAVEAWv-DIDQGE-AVRMAPEPG--GWHAATVP-VGAGTCYRYRVTNregiTLTVPDPAARAQWQDVHGPS 102 Ralstonia solan...
3M07_A        44 VRFRLWATGQQKVM--LRLAGK-DQEMQANGD--GWFTLDVAgVTPGTEYNFVLSDg----MVVPDPASRAQKTDVNGPS 114 Salmonella ente...
WP_003972842   1 mQFEVWAPQAGRVT--LRCDGA-TRALERDPErpGWWCGEAPaRD-GSRYGFAVDDg---P-VLPDPRSRRQPDGPDGLS 72  Streptomyces li...
WP_010976096  24 CRFRLWAPDEREVD--LVLGGA-VHKMQSLDG--GWFEITLA-AKAGERYCFRLADg----TEVADPASSAQEREASGTS 93  Sinorhizobium m...
1EH9_A        83 QIIQ-Es---KEFNNETF--LKKEDLIIYEIHVGTFtpeGTFEGVIRKLDYLKDLGITAIEIMPIAQFPGKRDWGYDGVY 156 Sulfolobus solf...
Q10769        73 QRWEpPgqfgAARTDTGWpgRSVEGAVIYELHIGTFttaGTFDAAIEKLDYLVDLGIDFVELMPVNSFAGTRGWGYDGVL 152 Mycobacterium t...
BAC18835      85 EVISpD----FAWSDDAWtgRILPGSVIYELHVGTFspsGDFDGVIERLDYLKDLGVTAVELMPVQPFGGNRNWGYDGVL 160 Corynebacterium...
AAL20478      91 YVVDpGs---YTWRNTGWkgSRWEQAVVYEMHTGTFtpeGTFRAAIAKLPYLAELGVTVIEVMPVAQFGGERGWGYDGVL 167 Salmonella ente...
CAE33358      89 VVVGpDr---YPWRHTGWrgRPWQDSVIYEAHAGLC---GGYAGLRRRLPEVARLGVTLLELMPIADFPGPRNWGYDGVL 162 Bordetella bron...
AAM35318      92 AVQPtDg---YAWQNTQWqgRPWDEAVIYEVHVGTC---GGYAGVQAQLPQLAAMGITAVELMPLSAFPGAHNWGYDGVL 165 Xanthomonas axo...
CAD17388     103 LVVDpLr---YAWQHPGWmgRPWHETVLYELHVGAL---GGFDGVRARLPELARLGITAIELMPVAEFPGARNWGYDGVL 176 Ralstonia solan...
3M07_A       115 YVVDpGs---YTWRNTGWkgSRWEQAVVYEMHTGTFtpeGTFRAAIAKLPYLAELGVTVIEVMPVAQFGGERGWGYDGVL 191 Salmonella ente...
WP_003972842  73 AVVDhGr---YAWR-TPWagRPLPGGVLYELHVGTYtpeGTLDAAAERLGHLAGLGVTHVELMPLCPFPGRHGWGYEGVS 148 Streptomyces li...
WP_010976096  94 IVVDhAa---YEWQTSSWrgRPWEEAVISELHVGCFtpeGTFRAAIERLPHLAGAGITAIEIMPVAQFPGVRGWGYDGVL 170 Sinorhizobium m...
1EH9_A       157 LYAVQNSYGGPEGFRKLVDEAHKKGLGVILDVVYNHVGPEGNYMVKLGP-YFSQKYKTPWGLTFNFDDAesdEVRKFILE 235 Sulfolobus solf...
Q10769       153 WYSVHEPYGGPDGLVRFIDACHARRLGVLIDAVFNHLGPSGNYLPRFGP-YLSS-ASNPWGDGINIAGAdsdEVRHYIID 230 Mycobacterium t...
BAC18835     161 WHAVHSGYGGPVGLKKLVDACHNAGIAVYLDVVYNHFGPDGNYNGMFAP-YTAG-GSTGWGEVVNINGPesdEVRRYILD 238 Corynebacterium...
AAL20478     168 LYAPHSAYGTPDDFKAFIDAAHGYGLSVVLDIVLNHFGPEGNYLPLLAPaFFHKERMTPWGNGIAYDVD---AVRRYIIE 244 Salmonella ente...
CAE33358     163 PYAPDTAYGTPDELKALIDAAHGLQMGVMLDVVYNHFGPDGNYLHRYAAdFFDARADTPWGAAIDYRQQ---AVQRYFID 239 Bordetella bron...
AAM35318     166 PYAPVEAYGTPDELKALIDAAHGHGLMVLLDVVYNHFGPDGNYLHSYAApFFNEDKPTPWGAAIDFRKP---PVQRYFLD 242 Xanthomonas axo...
CAD17388     177 PFAPEAGYGPPDALKALIDSAHGLGLMVFLDVVYNHFGPEGNYLHHYARrVFRDDVHTPWGAAIDFRQP---EVRAFFLH 253 Ralstonia solan...
3M07_A       192 LYAPHSAYGTPDDFKAFIDAAHGYGLSVVLDIVLNHFGPEGNYLPLLAPaFFHKERMTPWGNGIAYDVd---AVRRYIIE 268 Salmonella ente...
WP_003972842 149 LWAVHEPYGGPEALKRFVDRAHDLGLGVVLDVVHNHLGPSGNHLPAFGP-YFTDTHHTPWGVAVNLDAPgsdEVRAYLVD 227 Streptomyces li...
WP_010976096 171 HYAPHNAYGKPDDLKALVDAAHSLGLTVLLDVVYNHFGPEGNYLSRYASrFFNKDRPTPWGASIAFEEE---AVRRYFIE 247 Sinorhizobium m...
1EH9_A       236 NVEYWIKEYNVDGFRLDAVHAIIDTSpkhILEEIADVVHKYN------RIVIAESDLNDPRVVNPKEKC---G-YNIDAQ 305 Sulfolobus solf...
Q10769       231 CALRWMRDFHADGLRLDAVHALVDTTavhVLEELANATRWLSgqlgrpLSLIAETDRNDPRLITRPSHG---G-YGITAQ 306 Mycobacterium t...
BAC18835     239 AVTRWFEEFHIDGLRLDAVHSLDDNGafpLLEQMTVASEAIAaatgipRSLIAESDLNDPRLVTSREAG---G-YGLHAQ 314 Corynebacterium...
AAL20478     245 APLYWLTEYHLDGLRFDAIDQIEDSSarhVLVEIAQRIREDItd--rpIHLTTEDSRNIISLHPRDQDGn--A-PLFTAE 319 Salmonella ente...
CAE33358     240 NALYWLREYRFDGLRLDAVHAMGRTD---WLAGLAREARAACpd--rrVHLVVENDANQASLLAQG----------FDAQ 304 Bordetella bron...
AAM35318     243 NALMWLHEYGFDGLRLDAVHAISPNA---FLDTLRETIEASLpag-rhVHLVLENEANQASQLQRG----------YTAQ 308 Xanthomonas axo...
CAD17388     254 NALMWLMEYRFDGLRLDAVHAIGARD---WLEELAARVRQAVepg-rhVHLVLENEHNTASLLRGAPPGtlgT-GAFEAQ 328 Ralstonia solan...
3M07_A       269 APLYWLTEYHLDGLRFDAIDQIEDSSarhVLVEIAQRIREDItd--rpIHLTTEDSRNIISLHPRDQDGn--A-PLFTAE 343 Salmonella ente...
WP_003972842 228 SALAWLRDYRLDGLRLDAVHALADTRachFLEQLSTAVDGLAadlerpLFLIAESDLNDPRIITPRAEG---G-LGVHAQ 303 Streptomyces li...
WP_010976096 248 NALYWLGHFRFDGLRLDATEQIRDTTkphFLVALEHEVREAFae--rqIHLVLEDAHRRRSLLQRDASG---ArMLFDAA 322 Sinorhizobium m...
1EH9_A       306 WVDDFHHSIHAYLTGERQGYYTDFG--NLDDIVKSYKDVFVYDGKYSNFR-RKTHGEPV--GE--LDGCNFVVYIQNHDQ 378 Sulfolobus solf...
Q10769       307 WNDDIHHAIHTAVSGERQGYYADFG--SLATLAYTLRNGYFHAGTYSSFR-RRRHGRAL--DTsaIPATRLLAYTCTHDQ 381 Mycobacterium t...
BAC18835     315 WVDDIHHALHTLVSGERNGYYSDFG--DTATLASTLEKVFHHTGQVSTFR-GRRHGREI--RRdvTPASRFVTYTTTHDQ 389 Corynebacterium...
AAL20478     320 WNDDFHNAVHVFATGETQAYYNDFAdaPEKHLARALAEGFAYQGEISP-QtGEPRGVKS--TG--QPPVAFVDFIQNHDQ 394 Salmonella ente...
CAE33358     305 WNDDAHHVLHHLLTGERQGYYADYAqaPAALLARALGEGYVYQGQAAPTRgGRARGEPS--AH--LPPWAFVLFLHNHDQ 380 Bordetella bron...
AAM35318     309 WDDDFHNALHVLLTGEEEGYYAAFAdkPTEHLARVLGEGFAYQGEPDPR--GHVRGEPS--GA--LPPHKFVVFAQNHDQ 382 Xanthomonas axo...
CAD17388     329 WNDDGHNALHVLLTGEHEAYYAAYAdaPAQRLARVLQDGFCYQGEPSVIHdGAPRGEPS--GW--LPPTAFVLFLQNHDQ 404 Ralstonia solan...
3M07_A       344 WNDDFHNAVHVFATGETQAYYNDFAdaPEKHLARALAEGFAYQGEISPQT-GEPRGVKS--TG--QPPVAFVDFIQNHDQ 418 Salmonella ente...
WP_003972842 304 WNDDFHHALHAALTGESQGYYADFArdPLAALAKTLIRGYFHDGTYSSFR-GRSHGRALdrGR--VAAHRLTGYSQTHDQ 380 Streptomyces li...
WP_010976096 323 WNDDLHNALHVVATGETKGHYRLFAdePWGKIRSALAEGFAVPAKEDNF---SPEGSRA--R---VPPQGRVNFLQNHDQ 394 Sinorhizobium m...
1EH9_A       379 VGNRGKGERIIKLVDR--ESYKIAAALYLLSPYIPMIFMGEEYGEENPFYFFSDFSDsKLIQGVREGRKKE--------- 447 Sulfolobus solf...
Q10769       382 VGNRALGDRPSQYLTG--GQLAIKAALTLGSPYTAMLFMGEEWGASSPFQFFCSHPEpELAHSTVAGRKEEfaeh----- 454 Mycobacterium t...
BAC18835     390 TGNRAVGDRPSMNLTP--AQQMLKAAVIYCSPYTPMLFMGEEYGATTPFAFFCSHTDdELNRLTSEGRKREfarl----- 462 Corynebacterium...
AAL20478     395 VGNRAQGDRLITLAGA--ERTKVLLATLLLSPHIPLLFMGEEYGESRPFLFFTDFHG-DLARAVREGRAKEfad------ 465 Salmonella ente...
CAE33358     381 VGNRADGLRLTSLLAPgsPALRAAIALQLLAPHIPLLFMGEEYGSTAPFFYFTSHGP-ELAAAVRAGRAREfaas----- 454 Bordetella bron...
AAM35318     383 IGNRARGERLTVLVSP--QRLRAALALTALTPMIPLFFMGEPWGAKQPFLFFTDFGP-PLDEAVREGRRREfahfaafad 459 Xanthomonas axo...
CAD17388     405 IGNRAFGERLTRLAHP--DALRAAQALLLLSPQIPLLFMGEEWGCLRPFLYFTSHHG-ALAEAVREGRRREfarfaafad 481 Ralstonia solan...
3M07_A       419 VGNRAQGDRLITLAGA--ERTKVLLATLLLSPHIPLLFMGEEYGESRPFLFFTDFHG-DLARAVREGRAKEfad------ 489 Salmonella ente...
WP_003972842 381 VGNRAQGDRLASLVSP--GLAACAATLTLTAPFTPMLFMGEEWAAGTPWQFFTDHTDpQLAQAVRQGRRREfaah----- 453 Streptomyces li...
WP_010976096 395 IGNRAFGERLASLLQE--DSLRVLAAMHMLTPQIPLLFMGEEYGETQPFYFFSDYQG-EIAAAIRLGRRDEaenf----- 466 Sinorhizobium m...
1EH9_A       448 ---NG-----QDTDPQDESTFNASKLSWKID-----EEIFSFYKILIKMRKELSI----ACDRRVNVVNGe-NWLIIk-- 507 Sulfolobus solf...
Q10769       455 gwaAD-----DIPDPQDPQTFQRCKLNWAEAgsgehARLHRFYRDLIALRHNEADladpWLDHLMVDYDEq-QRWVVm-- 526 Mycobacterium t...
BAC18835     463 gwdPE-----TIPTPSEESTFTDSKLDWSFTpe--qENILEGYRTLLRLRRELGms-qpDLLSMEISNG---PGWISm-- 529 Corynebacterium...
AAL20478     466 -hagE-----NVPDPNAPETFQRSKLNWKQQhseegKAWLAFTRELLLLRQKHIVpllsAARESSGTVLQtaPGFIAvsw 539 Salmonella ente...
CAE33358     455 mhdCD-----PPPDPNDPDTYRRSCPWP--PpgaerQAWFEYYRELLRLRARLLGgrltGARADGAAALG--PAAVRaaw 525 Bordetella bron...
AAM35318     460 eaqRA-----TIPDPNSHATFAASRSPIADAahgdgAQWASWFKALLDVRRQWLVpglaQARAVRASVLA--DGAVTatw 532 Xanthomonas axo...
CAD17388     482 phqRE-----RIPDPNDERTFLDSQPGSTDPtlpeqLDWLNRTQGLLALRHARIVprlpGTRALDAVPLG--ATGALarw 554 Ralstonia solan...
3M07_A       490 -haGE-----NVPDPNAPETFQRSKLNWKQQhseegKAWLAFTRELLLLRQKHIVpllsAARESSGTVLQtaPGFIAvsw 563 Salmonella ente...
WP_003972842 454 gwrEE-----DVPDPQDPATRERSCLDWSEPerephARVLDWYRRLIALRAEQPDltdpDLADTRVAYDGt-GRWLAf-- 525 Streptomyces li...
WP_010976096 467 gglPEgktmdDLPDPLDPDVFAGSKLRWNRAtspagERHLAYVRDLAVIRQRHIVpliaGTAVPDGRAYEtkDGIIAvdw 546 Sinorhizobium m...
1EH9_A       508 ---GR-EYFSLYVFSKSSIEVK 525 Sulfolobus solfataricus
Q10769       527 --rRG-QLMIACNLGAEPTCVP 545 Mycobacterium tuberculosis
BAC18835     530 --aNG-DGILVANFSDSDVEVP 548 Corynebacterium efficiens YS-314
AAL20478     540 rfpGG-TLSLALNISATTVLLP 560 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
CAE33358     526 rlgDGaRLTLYANLLPGSVIVP 547 Bordetella bronchiseptica RB50
AAM35318     533 elpGG-LWHIAFNVGTQPVPLP 553 Xanthomonas axonopodis pv. citri str. 306
CAD17388     555 rlgDGsVLTLAINLGTQPVAVP 576 Ralstonia solanacearum GMI1000
3M07_A       564 rfpGG-TLSLALNISATTVLLP 584 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
WP_003972842 526 --rRG-DIRVAVNLGTEPAAIP 544 Streptomyces lividans
WP_010976096 547 qfgEA-CLELRVNLLHETHAVP 567 Sinorhizobium meliloti
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