19115952 1116 EKDKTNeeknkdevkaemtqPVvnqdshdlqdqlattptaptafhyrpgllqpsqtsvqhccwaLSQYYGl-EAKFRSLK 1194 fission yeast 14601352 472 tlariirlfysgraglvsvqwgrivellhrlgavgvswaaglgeprsssatvaeevvddvlagvvnrllG--VSRLRPGQ 549 Aeropyrum pernix 19552119 4 TREEAN--------------NL------------------------------------------LAGIAGp-GAQLRDDQ 26 Corynebacterium g... 15833536 1 --------------------------------------------------------------------MG--RAGRGIDS 10 Escherichia coli ... 15833537 -------------------------------------------------------------------------------- Escherichia coli ... 15833538 2 EKHAAE--------------LL------------------------------------------LQRMLGntTATFREGQ 25 Escherichia coli ... 15639097 29 TDNPACdahmshdviartaqAVfgiralfpwqrlvianildaahacthttpfaaagssqtdatrVTHVDDaqPEDNFVGA 108 Treponema pallidum 15803946 -------------------------------------------------------------------------------- Escherichia coli ... 15803947 2 EKHAAE--------------LL------------------------------------------LQRMLGntTATFREGQ 25 Escherichia coli ... 17230943 5 NKEKAL--------------LL------------------------------------------LRQALDnpTSNFRPGQ 28 Nostoc sp. PCC 7120
19115952 1195 QfqSVYFSLLNR------MNLITVLPTGGGKSLSFLIPALIEkkrqtPGkvmnmVTLVLVPMMSLRQDMMLRVNEKGLLV 1268 fission yeast 14601352 550 E--AVLRRISRVyaslspSVTIAVMPTGYGKSLLFQAPARGLay-lgYGa----LTLVVTPLKALMRDQTRAALGRGLAA 622 Aeropyrum pernix 19552119 27 W--VAIDALVNQr-----KRMLVVQRTGWGKSAVYFIAAKLLra-rgAG-----AAVIISPLLALMRNQVASAERAGIKA 93 Corynebacterium g... 15833536 11 A--VGILLCGSE------DRAIHKFFRESAFPAEAQIHEILN-------------VLSVNDGLTLRGIEQRTNLRYG-QI 68 Escherichia coli ... 15833537 -------------------------------------------------------------------------------- Escherichia coli ... 15833538 26 W--EAIDAVVNQr-----RKLLVVQRTGWGKSAVYFIASKIFrd-rgAG-----PTIIISPLLALMRNQVAAAERLGITA 92 Escherichia coli ... 15639097 109 M--QDTRFDQDGvs---rAHQVVLLPTGAGKSLCFQVPALFL-----EG-----PTLVVYPLLSLMRDQCRRMQAVGFSV 173 Treponema pallidum 15803946 -------------------------------------------------------------------------------- Escherichia coli ... 15803947 26 W--EAIDAVVNQr-----RKLLVVQRTGWGKSAVYFIASKIFrd-rgAG-----PTIIISPLLALMRNQVAAAERLGITA 92 Escherichia coli ... 17230943 29 W--EAIEELIERr-----SRLLVVQRTGWGKSLVYFLATKLLrd-kgAG-----CTLLISPLLALMRNQIAAAQRIGIKA 95 Nostoc sp. PCC 7120
19115952 1269 CSGNWTAFKDVRLTLETQLPD----------------------------------------LFILTYESALTNSGl---- 1304 fission yeast 14601352 623 CYIDSSLSLKARGEVLRAAAMg--------------------------------------lIDLLYIAPERFEDA----- 659 Aeropyrum pernix 19552119 94 ATLNSA-NMTEWETIQQQVVSg--------------------------------------dADVLLISPERLNNP----- 129 Corynebacterium g... 15833536 69 EKALKLLVAENPSPVVYTEKLw--------------------------------------rRTIVSFSPDHERIN----- 105 Escherichia coli ... 15833537 -------------------------------------------------------------------------------- Escherichia coli ... 15833538 93 ETLNST-NREEWQRISDKLLQg--------------------------------------eVDCLLVSPERLANQ----- 128 Escherichia coli ... 15639097 174 ILLRGGLNAQERAYMYAQLDRcaeaygrmrgvtppahqtaefsladsisfdaslfsddvstFSKVVHVDERLAQKrtesr 253 Treponema pallidum 15803946 -------------------------------------------------------------------------------- Escherichia coli ... 15803947 93 ETLNST-NREEWQRISDKLLQg--------------------------------------eVDCLLVSPERLANQ----- 128 Escherichia coli ... 17230943 96 ATINSS-NQDEWRAVKTQLLAg--------------------------------------qVDILLISPERLANN----- 131 Nostoc sp. PCC 7120
19115952 1305 -----------RFFESLAt---LGRLARVVIDEAHLLLTSG-AWRTALSRASRLSGLY------APLHLLSATFPRQLEM 1363 fission yeast 14601352 660 -----------RIREVVE----GGRLALAVLDEAHTASRWGeTFRNSYLYMAKTLASLrleegwPPILALTATATLDIIE 724 Aeropyrum pernix 19552119 130 -----------DFRDTILpr-lAAETGLVVVDEAHCISDWGhDFRPDYRRIRDLLAGLap---nIPVLATTATANDRVVE 194 Corynebacterium g... 15833536 106 -----------HLMNQRKs---ELADVESYITTKECKMQF---LRRALDEPGAEHCG--------KCSSC--LQHPLLSP 158 Escherichia coli ... 15833537 1 ---------------------------------------MGpRFSPGLPTYIRYFAQLpa---nTPVLGTTATANNRVVE 38 Escherichia coli ... 15833538 129 -----------DFIETVLyp-iADHIGLLVVDEAHCISDWGhDFRPDYRRILDILRNYl----rIPLFWVQPRQRITVSL 192 Escherichia coli ... 15639097 254 rgvciiaspeiLTQPALRarvrACRVAHLVIDEAHCVSEWGdSFRPDYVRLGELVQDLa----pQVVTAFTATASQTVLA 329 Treponema pallidum 15803946 -------------------------------------------------------------------------------- Escherichia coli ... 15803947 129 -----------DFIETVLyp-iADHIGLLVVDEAHCISDWGhDFRPDYRRILDILRNYl----rIPLFWVQPRQRITVSL 192 Escherichia coli ... 17230943 132 -----------DFRENILlp-iSQSIGLFVVDEAHCISDWGhDFRPDYRRIVRILQGLpk---nIPILATTATANNRVID 196 Nostoc sp. PCC 7120
19115952 1364 VARQTFCTNFY--------------------VLRETSTARENIFYFLHPYDntEFLLDLR------------TLMKrtKV 1411 fission yeast 14601352 725 SLVAMLGAADYsvvdleedgaipgegspeetIVYRIAPVRPNIAVEARIAPpgRARLDVAaehvrelaawatGVSEswVG 804 Aeropyrum pernix 19552119 195 DVRAQLGDGTG---------------------LLRGGLDRESLYLSVVNLL--NPTERPA------------WLAT--HL 237 Corynebacterium g... 15833536 159 DIDSGLLHAA---------------------NLFIKHADLSLNLNKQVAAG---AFTQYG------------FKGN---L 199 Escherichia coli ... 15833537 39 DIRQQLGDIV----------------------IQRGTLARESLALDALVLG--EHSSRLA------------WLAT--VI 80 Escherichia coli ... 15833538 193 RISVSNWVTL---------------------------------------------------------------------- 202 Escherichia coli ... 15639097 330 RIMEVLFGGRa--------------------HVLQGTVDRPNIRYTVRTVLckQTALTQLv------------------- 370 Treponema pallidum 15803946 1 ---------M----------------------IQRGTLARESLALDALVLG--EHSSRLA------------WLAT--VI 33 Escherichia coli ... 15803947 193 RISVSNWVTL---------------------------------------------------------------------- 202 Escherichia coli ... 17230943 197 DIIAQLGANLQ---------------------VVRGNLTRESLRLQNISLP--SPAARMA------------WLVE--QL 239 Nostoc sp. PCC 7120
19115952 1412 FEGDGRAIIFCRTKKDVEYIHRRLHQSdlfaHTHVTIYTGD-------VSDEERQMNFDAFRnaNGKTRIMIATKAFGLG 1484 fission yeast 14601352 805 AVFTGFVKSKAMDWANAETIASRLEPAl--gGVCEVLVYHGq-----mGEKRRKMVEERAAE--PRGRKIIVATKAFGMG 875 Aeropyrum pernix 19552119 238 KELTGSGIIYCLTVSAAHDLADALNSV----GWNVAAYTGr-------TEAGERERLEHALI--NNEIKALVATSALGMG 304 Corynebacterium g... 15833536 200 PASLQGSTGRILSRWGYSGWGKQVAQE-----KKTGRFSDE-------LVEACAEMVRQRWN--PHPEPTWVCCV----- 260 Escherichia coli ... 15833537 81 PQFSKSGIVYTLTTRDAELVAEWLRKN----GISAFAYYSGvtcegaeDSNTAREYLEQALL--ANKIKVLVATTALGMG 154 Escherichia coli ... 15833538 -------------------------------------------------------------------------------- Escherichia coli ... 15639097 371 ARCVRPAVIFCARRVQVERVAHHLRTCl--sDTQIRFYHAG-------LQREEKETVERWFH--THDSAVLVTTCAWGMG 439 Treponema pallidum 15803946 34 PQFSKSGIVYTLTTRDAELVAEWLRKN----GISAFAYYSGvtcegaeDSNTAREYLEQALL--ANKIKVLVATTALGMG 107 Escherichia coli ... 15803947 -------------------------------------------------------------------------------- Escherichia coli ... 17230943 240 PQLPGSGIIYTLTVRDANRVANWLQTQ----GINAKSYHSd-------LESDIRITLEDELL--NNQIKALVATTALGMG 306 Nostoc sp. PCC 7120
19115952 1485 INYMGVRLVVHYGLPASSMDYVQETGRAGRDGKYAIAALFYEKYDSTWSSYVEDSMKNfln---dnTMCVRSFLASEMDG 1561 fission yeast 14601352 876 VDIRNLRWTLHLFPSDSVEDLVQEIGRAGRDGLPARSLVLFDPEDFRVRRAMGLRQLPrlssvlalYNSLVELHGREESY 955 Aeropyrum pernix 19552119 305 FDKPDLGFVVHMGSPSSPVSYYQQIGRAGRGTARADVILLPGTEDKEIWEYFASVSFPreevvrqlLAVLTDEAQSTVK- 383 Corynebacterium g... 15833536 261 ---P-S--LKHLDLVPDFESTSTWFLILPGDWRRNLAYLLLMPLKKSWTIHRRKCSKT--------VSTSVKISTGRL-- 324 Escherichia coli ... 15833537 155 FDKPDLGFVIHYQMPGSIVGYY---------------------------------------------------------- 176 Escherichia coli ... 15833538 -------------------------------------------------------------------------------- Escherichia coli ... 15639097 440 VDKPNVRTVIHVDAPLTVEAYVQEVGRAGRDGMRADAFLLWSPRDAR-SIETLPHA---------------QR--VRAHV 501 Treponema pallidum 15803946 108 FDKPDLGFVIHYQMPGSIVGYY---------------------------------------------------------- 129 Escherichia coli ... 15803947 -------------------------------------------------------------------------------- Escherichia coli ... 17230943 307 FDKPDLGFVIHYQRPGSVVHYYQQVGRAGRAVDIAYGILLSGDEDEEITNYFINTAFPpqihtqqvLNILNQEEGLSVPQ 386 Nostoc sp. PCC 7120
19115952 1562 ECVCCASFAnCVYCSrcSDSLLGEEsTVSTMYGvKPTLPETPKp--AIATHSRYNASFSSSPPPQPG----NSSGMSAMN 1635 fission yeast 14601352 956 TLVLTPPAVpPKVVR--LLDILRTSgLLDYSITrRLHLYRLRKgvsWRDLEEAGVTPRLVLPRLGIVgfeeKVPPGEMLE 1033 Aeropyrum pernix 19552119 384 LESQVDLSR-SRLEQ--VLKVLDVDg--AVKRV-RGGWVSTGQ---EWIYDAERYAGLEQARKIEQQ----SMVNYQNTT 450 Corynebacterium g... 15833536 -------------------------------------------------------------------------------- Escherichia coli ... 15833537 -------------------------------------------------------------------------------- Escherichia coli ... 15833538 -------------------------------------------------------------------------------- Escherichia coli ... 15639097 502 LRHFAESGR-CRRAV--LLESLGEQ---NVCAG-CDVCAGTARf-vCEDVEALLQFLKKNARRFTVS----SLVQHLALH 569 Treponema pallidum 15803946 -------------------------------------------------------------------------------- Escherichia coli ... 15803947 -------------------------------------------------------------------------------- Escherichia coli ... 17230943 387 LEQKLNLSR-GQIDK--VLKLLSLEsPSPVTKI-DSKWYVTAI---NYQYDEQKIANLTAIRRQEQA----TMSAYMQSQ 455 Nostoc sp. PCC 7120
19115952 1636 TNTTSTTPVSLSELSEITLFPSSVSPTWKKSFGNANTNLKYGLEDMSLSHrr----gHKRTYDEHLNN-----VQQGVNH 1706 fission yeast 14601352 1034 PASLSIKLCISPDNSFEIFYGRHGNTGRECRRAVIERSGVALLIDLNPDVrhrsitkPTPDLLVYHARlasleALKVERL 1113 Aeropyrum pernix 19552119 451 ECRMLYLRKELDDVEATTPCGRCDNCTGKTWG-LDTDASITLKVDQQLQT-------PGVKIAPRKMW-----PTGISVR 517 Corynebacterium g... 15833536 -------------------------------------------------------------------------------- Escherichia coli ... 15833537 -------------------------------------------------------------------------------- Escherichia coli ... 15833538 -------------------------------------------------------------------------------- Escherichia coli ... 15639097 570 QKVLSVADVRALLYYALETGRVKKKHSLLWGDVLYVAR------------------------------------------ 607 Treponema pallidum 15803946 -------------------------------------------------------------------------------- Escherichia coli ... 15803947 -------------------------------------------------------------------------------- Escherichia coli ... 17230943 456 QCLMAFLATELDDANPQN-CGKCAVCVGRPLLPVNCSIEMLNQAVLYLRR-------SQQIIEPRKQW-----PSQALLS 522 Nostoc sp. PCC 7120
19115952 1707 DMNRVhgs---vgGMSGIVGIGIgigdgd-------------------------------gdgdvdSRtih--------- 1743 fission yeast 14601352 1114 RKLLEslsglrgeKSSQAFREGVreyfnkpllrplpenpekalkqprsiecagvskcralaatlerLVevlgplgvtiav 1193 Aeropyrum pernix 19552119 518 GKIAGl-------EEGRALGRLNdiargpalk--------------------------alldsgaySDd----------- 553 Corynebacterium g... 15833536 -------------------------------------------------------------------------------- Escherichia coli ... 15833537 -------------------------------------------------------------------------------- Escherichia coli ... 15833538 -------------------------------------------------------------------------------- Escherichia coli ... 15639097 -------------------------------------------------------------------------------- Treponema pallidum 15803946 -------------------------------------------------------------------------------- Escherichia coli ... 15803947 -------------------------------------------------------------------------------- Escherichia coli ... 17230943 523 YKFSGnisnnlraQEGRALSLWGdagwgelvk--------------------------qgkyrdnyFNd----------- 565 Nostoc sp. PCC 7120
19115952 1744 ----faeYKSRVQAVKKQWVDSTDISAQLERFFRVYKDECLSCTLGNPDTEIRAHTGK--ACPVRLSTCYKCGKADHNLR 1817 fission yeast 14601352 1194 psgearaSFLRAYSSLFPVEPRIVGVRKVLNRLKAGGVAAADLGYVVAVTHKESQYNMllSTVEGSGYPYVTVVHAKMPV 1273 Aeropyrum pernix 19552119 554 -------PWMARIIEVLKNWDWTNRPANVVALGNTNFGSTEMIIQVAQSIAAVGRMNF--AGVLPAAPGAEEVMAQNSAY 624 Corynebacterium g... 15833536 -------------------------------------------------------------------------------- Escherichia coli ... 15833537 -------------------------------------------------------------------------------- Escherichia coli ... 15833538 -------------------------------------------------------------------------------- Escherichia coli ... 15639097 -------------------------------------------------------------------------------- Treponema pallidum 15803946 -------------------------------------------------------------------------------- Escherichia coli ... 15803947 -------------------------------------------------------------------------------- Escherichia coli ... 17230943 566 -------VLVQGTVEMIKRWQPQPFPSWVTCVP--SLNRPELVPNFAQRLAEKLGITF--VPIVRKVKQTQLQKDMSNSY 634 Nostoc sp. PCC 7120
Jiyao W et al.(2023). "The conserved domain database in 2023.",