Conserved Protein Domain Family
Cas4

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COG1468: Cas4 
CRISPR/Cas system-associated exonuclease Cas4, RecB family [Defense mechanisms]
CRISPR/Cas system-associated exonuclease Cas4, RecB family is part of the Pathway/BioSystem: CRISPR-Cas system
Statistics
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PSSM-Id: 441077
Aligned: 437 rows
Threshold Bit Score: 52.6536
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_010876857  24 INii---kcGDq-----M---------------SVA---------------------------VSMISEF-MFCPLKLYL 52 
AEG14506       1 -----------------Me--------------VFS---------------------------YSRLSKY-ESCPAAFYR 21 
AFU59550       1 -----------------MlgsrnlreiveknldKLQedlsvki--------------dkknpdKIHAIEA-TGCTRFAYY 48 
CUR51339       1 -----------------Mqtiq-------eqkdCINaveidlpvgivnflkrrhgkkyeapqsRYSVTNI-VGCQRKAFY 55 
WP_011448852  77 saesirefiKNeffipyLtkh----------apRLS---------------------------HEQIEAFaVACDRWIRY 119
WP_011916988   1 -----------------Mve-----------ldVMKg-------------------------sYSKLQLF-ERCQRAFYF 26 
WP_083773998   1 -----------------M----------------IR---------------------------PSDLHTF-GYCPRLAFF 19 
WP_015232356   1 -----------------MggrretdnnrnknkaIIY---------------------------PSELHSY-FYCPRVYFF 35 
WP_075055694   1 -----------------MlgdrnlrgmiekaldRLNddlnikv--------------dkknpdRIHALEA-ALCTRFSYY 48 
WP_103287359  28 TKtdiydiiEDtf--nsLl--------------KVEd-------------------------dAISVEEV-SRCLREAYF 65 
WP_010876857  53 -REVLGVRe-------PMRPEAVHLR-KAYldfraa-aesitRKL-EDDvgvdelesmlmedlerilgdlnegerdliae 121
AEG14506      22 -HYCLHAEg-------VPSEASVTGK-AAHavieaamklgckEEMfFRVmseialat----------------------- 69 
AFU59550      49 -ERRDPLPsd-----nVSKISSLLGNaMRHsfg----------------------------------------------- 75 
CUR51339      56 kELGIQEEellrdatvESMWASVRGD-FLH------------EITray-------------------------------- 90 
WP_011448852 120 lRVFISPDgt-----gIEDPKKLIST-IFH-------------------------------------------------- 143
WP_011916988  27 -KYVKNME--------YTTPAMEFGK-IIH------------EEL-AKFlttgaeg------------------------ 59 
WP_083773998  20 -ELYMPRRrg-----lLEILRLFIGR-AFH------------AMFml--------------------------------- 47 
WP_015232356  36 -ETHMKKKrg-----fFKRVRLFLGS-LFH------------YTFrl--------------------------------- 63 
WP_075055694  49 -ERKDPLSed-----nASKVSILLSHgIRNals----------------------------------------------- 75 
WP_103287359  66 -ERKSPMErt-----qKQMLEVIIQRgILN-------------------------------------------------- 89 
WP_010876857 122 pmvfevrtmalrigramnilggqcD-Rvasll-fppliRD------------YPI-YDpsi--------elhGRV-SMEI 177
AEG14506      70 -----------------spleikpE-QvfiltyrnpvlREfhpdnrveehfvVPL-DDedpfa-----pkvqGYIdLWR- 124
AFU59550      76 -----------------------------------ntrGE------------YKVegl-----------sleVNAdLIIa 97 
CUR51339      91 ---------------------kwrElDie---------------------hfVTLrDGrva--------tvaGRLdMYDw 120
WP_011448852 144 ------------------------S-------------SE------------YTM-SSdflcddg-evvkisGRPdALLF 172
WP_011916988  60 -----------------knvkqfiTpKvrryvgvnpeyVE------------LELkfnlps------gteytAVIdLFE- 103
WP_083773998  48 -----------------------rD-Kvkg------yiSEh----------dLVLsLNenv--------mivGRAdAIKV 79 
WP_015232356  64 -----------------------rD-Iikh------ysYE------------IPM-ETdlgs------viirGRPdAFKI 94 
WP_075055694  76 -----------------------------------nikGE------------YKVdsl-----------tldVNAdMVIg 97 
WP_103287359  90 ------------------------Tfak-------pvrGE------------VSI-ESsddnygknvkirlvGTAdRVE- 124
WP_010876857 178 S-Gg---S-YHPLKFRTS-Lpp----asG--VWPSDSLEITAQAILVEReFETeVMVSFIDYIL-PAERRPVVI--DYRR 242
AEG14506     125 --Dg---ShIELIDWKTNyKa------yK--P--TDTHQLGLYAWYLSRrTGRaV-RGKLVFLR-LNEVLEHEF--SYRD 185
AFU59550      98 D-E-------FVVRFEVV-Qtlp------evPHPRHLLYLNACLFAFNKd------EGFLIYMTaEGKTVEFSVtkNNRM 156
CUR51339     121 KtN-------TVIDLKTT-KfvkwqiksGflPKPEHILQVQCYSTMFPKiMp--VQNLTLVYAD-MNDLVAFKV--QPRD 187
WP_011448852 173 --DpgtqEp-VVVEYK-GrKe------sD--P-TQDLAQTSLYAWLVSRsIGIt-pRVDMLYLE-DP-VPLVRY--DSSA 234
WP_011916988 104 --Nn---T-AKVLDWKTGwQ------------KEADIRQLYIYAYALKKn-GVkPEKLSFFYLR-FDKEDEFAM--STDK 161
WP_083773998  80 A-Eg---K-AHIIERKSS-Kap----rkG--AWVSDIIQAGAYGLMVARnYRPqEITVEVRYPT-AS--RVFKF--DSRL 142
WP_015232356  95 K-En---S-AYVIERKSS-Kpp----ykG--AWINDIMQAVAYSVILIReKDLkNVKIEIKYPN---KSRVFDL--NSEL 157
WP_075055694  98 D-E-------FVVRFEIV-Pelp------amPHPRHLLYLNACLFALGKd------EGILIYMTaDGRTTEYSVtkNNRM 156
WP_103287359 125 D-D-------CVVMFRIV-Kelp------eiPYAEHFMQMNAYLHIFNKe------EGVIAYFDnDGNEVEFIVpkNEAL 183
WP_010876857 243 REY-LFDVLDE---IRRITEDG-----------EV-PsvDLnPSRCAGCSLAEVC-S-----------------RE 284
AEG14506     186 MEN-AREWAYT---LAREIQDKlcmvnegadhrQLfPt-KVg-DACRECEYAVECiDgnlppvpgevktyqeaeal 255
AFU59550     157 FEE-VIRRARV---LSTLLKDG-----------KA-PivEPs-ELCLNCRYYERCyA-----------------RK 198
CUR51339     188 LTEwIAKRVQE---IEDAKASQ-----------VI-PkgEVt-GLCQFCSYQTKCsNdgngliekplsipknhlEE 247
WP_011448852 235 IHTlIGNHASLitlARRIKEGH-----------LPvPr-CKdPDLCKMCPYTA-CdTdfe------------viRP 285
WP_011916988 162 LNE-TIDWMDR---IEDSMNEKlfly---ssegEEe--fEKnYSSCKGCPYAKLClGediaskekaieiamyidel 228
WP_083773998 143 SAL-VLKAIDD---YLLVKKNG-----------IL-PaaKRg-RRCNSCPYREACfL-----------------LD 184
WP_015232356 158 TSM-LFKALDE---MVLIKYNN-----------IL-PyaKRg-NRCNKCPYRNECfS-----------------LD 199
WP_075055694 157 FEE-IVRRARV---LSTLLKDG-----------KV-PivEPs-DLCLKCKYYSRCyS-----------------RE 198
WP_103287359 184 YKE-TIRRVRI---LHTLLKNG-----------VV-PvvEPs-NMCSTCPYNELCyY-----------------PS 225
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