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National Research Council (US) Committee on Immunologically Compromised Rodents. Immunodeficient Rodents: A Guide to Their Immunobiology, Husbandry, and Use. Washington (DC): National Academies Press (US); 1989.
Immunodeficient Rodents: A Guide to Their Immunobiology, Husbandry, and Use.
Show details| Monoclonal Antibodies Reacting to Species-Specific Cell Surface Antigen | |||||||
|---|---|---|---|---|---|---|---|
| Cluster of Differentiation (CD) Designation | Human | Mouse | Rat | Guinea Pig | Hamster | Distribution | Description |
| CD1 | T6 Leu-6 OKT6 | Ly-38 | Langerhans' cells, thymocytes | Cortical thymocyte differentiation marker | |||
| CD2 | T11 OKT11 Leu-5b | Ly-37 | OX34 | All T cells forming E rosettes, NK cells | E-rosette receptor | ||
| CD3 | T3 OKT3 Leu-4 | Mature T cells | Constant portion of Ti receptor | ||||
| CD4 | T4 OKT4 Leu-3a | Ly-4 L3T4 | OX36 OX37 OX38 W3/25 OX35 | Helper/inducer T lymphocytes | A member of the class II-restricted T-cell population | ||
| CD5 | T1 OKT1 Leu-1 | Ly-1 Lyt-1 | R-1-3133 OX19 | 8BE6 | T cells, B-cell subset | ||
| CD6 | T12 | Mature T cells, Subpopulation of B cells | |||||
| CD8a | T8 OKT8 Leu-2a | Ly-2 Lyt-2 | OX8 OX9 OX10 | CT6 | Cytotoxic T lymphocytes (CTL) | CTL adhesion | |
| CD8b | Leu-2b | Ly-3 Lyt-3 | CTL | CTL adhesion | |||
| CD11a | LFA-1 | Ly-15 | Leukocytes and erythroid and myeloid stem cells | ||||
| CD11b | Mac-1 Leu-15 | Ly-40 | OX42 | Macrophages, granulocytes, Ly-1 B cells | C3bi receptor | ||
| CD16 | Leu-11a | NK cells, granulocytes | FcRlo | ||||
| CD20 | B1 Leu-1b | B lymphocytes, except plasma cells; follicular dendritic cells | |||||
| CD23 | CD23 | Ly-42 | B lymphocyte subsets, follicular dendritic cells | IgE Fc receptor | |||
| CD25 | TAC IL-2R | Ly-43 | OX39 ART-18 | 5C3? | Activated T cells, B cells | IL-2 receptor | |
| CD32 | FcR11 | Ly-17 Lym-20 | B, myeloid, and Langerhans' cells | Fc IgG2b/1 receptor | |||
| CD45 | T29/35 | Ly-5 T200 | OX22 L-CA | 201 | Panleukocyte, erythroblast, and follicular dendritic cells; thymocytes; and some B cells | ||
| CD45R | CD45R | Ly-5 B220 | OX51 | Pre-B and B cells, CTL, granulocytes, monocytes | |||
| Transferrin receptor | OKT9 | OX26 | Activated lymphocytes, monocytes | ||||
| Theta | Thy-1 | Thy-1 | OX7 Thy-1 | 154 | HO-13-4 | T cells, neurons, fibroblasts, and stem cells | Not present on human T cells |
| Ia | HLA-D (DR, DP, DQ) | H-2I (I-A, I-E | RT1B RT1D | P51 S11 S12 S34 | B cells, monocytes, activated T cells | MHC class II (Ia) antigens | |
| Others | Lyb-3 | B cells | |||||
| Lyb-7 | B and T lymphocytes, subsets of thymocytes, 15% of bone marrow cells | ||||||
| Lyb-5 | B lymphocyte subset | ||||||
| ThB | B lymphocytes, thymocytes | ||||||
| OX2 | Follicular dendritic cells | ||||||
SOURCES:
Murine hematopoietic cell surface antigen expression, K. L. Holmes and H. C. Morse III, eds., Immunol. Today 9:344–349, 1988.
The Lymphocyte: Structure and Function, 2d ed., J. J. Marchalonis, ed., Marcel Dekker, Inc., New York, 419 pp., 1988.
Differentiation Antigens in Lymphohemopoietic Tissues, M. Miyasaka and Z. Trnka, eds., Marcel Dekker, Inc., New York, 531 pp., 1988.
- Hematopoietic Cell Surface Antigens Mentioned in the Text - Immunodeficient Rode...Hematopoietic Cell Surface Antigens Mentioned in the Text - Immunodeficient Rodents
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