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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.

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Drugs and Lactation Database (LactMed®) [Internet].

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Triclabendazole

Last Revision: February 28, 2019.

CASRN: 68786-66-3

Chemical structure

Drug Levels and Effects

Summary of Use during Lactation

No information is available on the use of triclabendazole during breastfeeding. Because of protein binding of 96% to 99% for the drug and metabolites, exposure of the breastfed infant is likely to be low.

Drug Levels

Triclabendazole is metabolized into its active sulfoxide metabolite, which is further metabolized to the active sulfone metabolite. These drugs have half-lives of 8, 14, and 11 hours, respectively. Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Substance Identification

Substance Name

Triclabendazole

CAS Registry Number

68786-66-3

Drug Class

  • Breastfeeding
  • Lactation
  • Anti-Infective Agents
  • Antiparasitic Agents
  • Antiplatyhelmintic Agents

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Copyright Notice

Attribution Statement: LactMed is a registered trademark of the U.S. Department of Health and Human Services.

Bookshelf ID: NBK539279PMID: 30933456

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