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Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-.
CASRN: 135998-32-2
Drug Levels and Effects
Summary of Use during Lactation
Information in this record refers to the use of indium In 111 pentetate as a diagnostic agent. No information is available on the use of indium In 111 pentetate during breastfeeding. Because of the long half-life of indium 111 and the potential for serious adverse reactions in nursing infants, it is best to avoid the drug in women who wish to continue breastfeeding. If the drug is given, breastfeeding should be discontinued.
Drug Levels
Indium 111 decays by electron capture with 173 keV and 245 keV gamma emissions and a physical half-life of 2.8 days.[1] The manufacturer reports that 65% of the administered dose is excreted by the kidneys within 24 hours and 85% is excreted in 72 hours.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
References
- 1.
- Dilsizian V, Metter D, Palestro C, Zanzonico P. Advisory Committee on Medical Uses of Isotopes (ACMUI) Sub-Committee on Nursing Mother Guidelines for the Medical Administration of Radioactive Material. Final report submitted: January 31, 2019. 2019. https://www
.nrc.gov/docs /ML1903/ML19038A498.pdf.
Substance Identification
Substance Name
Indium In 111 Pentetate
CAS Registry Number
135998-32-2
Drug Class
Breast Feeding
Lactation
Milk, Human
Radiopharmaceuticals
Indium Radioisotopes
Diagnostic Agents
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
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