Figure 12. A: plot of percent inhibition for duplicate screen of the 1280 LOPAC screening deck.

Figure 12

A: plot of percent inhibition for duplicate screen of the 1280 LOPAC screening deck. LOPAC compounds (blue), minimum control, which should equal ~100% inhibition of signal readout (red), IC50 control compounds (yellow), and maximum control compounds, which should equal ~0% inhibition of signal readout (green), are indicated. B. Summary of HTS outcome and hit triage.

From: Identification of Inhibitors of Trypanosoma brucei Hexokinases

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