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Norris S, Weinstein J, Peterson K, et al. Drug Class Review: Direct Renin Inhibitors, Angiotensin Converting Enzyme Inhibitors, and Angiotensin II Receptor Blockers: Final Report [Internet]. Portland (OR): Oregon Health & Science University; 2010 Jan.
This publication is provided for historical reference only and the information may be out of date.
Drug Class Review: Direct Renin Inhibitors, Angiotensin Converting Enzyme Inhibitors, and Angiotensin II Receptor Blockers: Final Report [Internet].
Show details| Trade name | Active ingredient | Black box warnings |
|---|---|---|
| Tekturna® | Aliskiren | When used in pregnancy during the second and third trimesters, drugs that act directly on the renin-angiotensin system can cause injury and even death to the developing fetus. When pregnancy is detected, drug should be discontinued as soon as possible. |
| Lotensil® | Benazepril | |
| Capoten® | Captopril | |
| Vasotec® | Enalapril | |
| Monopril® | Fosinopril | |
| Prinivil® | Lisinopril | |
| Zestril® | Lisinopril | |
| Univasc® | Moexipril | |
| Accupril® | Quinapril | |
| Altace® | Ramipril | |
| Aceon® | Perindopril | |
| Mavik® | Trandolapril | |
| Cozaar® | Losartan | |
| Micardis® | Telmisartan | |
| Atacand® | Candesartan | |
| Teveten® | Eprosartan | |
| Avapro® | Irbesartan | |
| Benicar® | Olmesartan | |
| Rasilez® | Aliskiren | Drugs that act directly on the renin-angiotensin system can cause fetal and neonatal morbidity and death when administered to pregnant women. When pregnancy is detected, Rasilez should be discontinued as soon as possible. |
| Inhibace® | Cilazapril | When used in pregnancy, these drugs can cause injury or even death of the developing fetus. When pregnancy is detected, Inhibace should be discontinued as soon as possible. |
| Coversyl® | Perindopril | |
| Diovan® | Valsartan |
- Black box warnings for included drugs - Drug Class Review: Direct Renin Inhibito...Black box warnings for included drugs - Drug Class Review: Direct Renin Inhibitors, Angiotensin Converting Enzyme Inhibitors, and Angiotensin II Receptor Blockers
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