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Wilt TJ, Shaukat A, Shamliyan T, et al. Lactose Intolerance and Health. Rockville (MD): Agency for Healthcare Research and Quality (US); 2010 Feb. (Evidence Reports/Technology Assessments, No. 192.)

  • This publication is provided for historical reference only and the information may be out of date.

This publication is provided for historical reference only and the information may be out of date.

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Lactose Intolerance and Health.

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Appendix Table D5Gains in osteodensitometric values in prepubertal boys consuming low lactose diet (74% of the recommended daily Ca++ intake) after interventions with dairy foods (1,607 vs. 747mg/day of Ca++)53

OutcomeOutcome Mean ±STD in Active GroupOutcome Mean ± STD in Control GroupMean Difference (95% CI)
12 monthsGain in BMD
Radial metaphysis14.6±19.211.2±16.73.4 (−1.237; 8.037)
Radial diaphysis25.6±22.222.3±19.63.3 (−2.096; 8.696)
Femoral neck22±31.922.7±30−0.7 (−8.674; 7.274)
Femoral trochanter25±31.320.5±27.54.5 (−3.092; 12.092)
Femoral diaphysis76.3±31.764.3±3312 (3.675; 20.325)
Lumbar spine (L2–L4)25.9±1828.1±18.5−2.2 (−6.897; 2.497)
12 monthsGain in BMC (mg/year)
Radial metaphysis79±6271±568 (−7.219; 23.219)
Radial diaphysis93±5887±466 (−7.5; 19.5)
Femoral neck159±187164±222−5 (−57.752; 47.752)
Femoral trochanter472±198495±211−23 (−75.635; 29.635)
Femoral diaphysis4,460±22344,011±2119449 (−111.669; 1009.669)
Lumbar spine (L2–L4)1,971±8041,994±814−23 (−231.214; 185.214)
Mean of 5 appendicular skeletal sites1,064±470969±44995 (−23.35; 213.35)

Bold - statistically significant difference at 95% confidence level

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