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Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.

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Probe Reports from the NIH Molecular Libraries Program [Internet].

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Table 1Hsp70 Activators PubChem Summary*

StageAssay NameTestedActivePubChem AID
HTS (run by Scripps: MLSMR Liquids)Primary Hsp70 Assay (1X%ACT; cell-based)196,255821203
Hsp70 Titration Assay (3XEC50; cell-based)72121252
HeLa Cytotoxicity Counterscreen (3XIC50, cell-based)72211259
SAR (run by Scripps or the Assay Provider: powders)Hsp70 Titration Assay (3XEC50; cell-based)1611651950
Hsp70 Gene Expression QPCR Assay (cell-based)11651945
Hsp70 Western Blot Assay (cell-based)11651948
Hsp70 Downstream Target Gene Expression QPCR Assay (cell-based)11651964
HBEC QFRET ΔF508-CFTR Activation (cell-based)11651992
Aggregation suppression Assay (C. elegans larvae)11651963

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