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Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
Figure 11Ancillary and DMPK Profiles of ML227 Enantiomers
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- Review Progress towards small molecule inhibitors of the Menin-Mixed Lineage Leukemia (MLL) interaction with in vivo utility.[Probe Reports from the NIH Mol...]Review Progress towards small molecule inhibitors of the Menin-Mixed Lineage Leukemia (MLL) interaction with in vivo utility.Senter T, Gogliotti R, Han C, Locuson CW II, Morrison R, Daniels JS, Cierpicki T, Grembecka J, Lindsley CW, Stauffer SR. Probe Reports from the NIH Molecular Libraries Program. 2010
- Structure-Based Discovery of M-89 as a Highly Potent Inhibitor of the Menin-Mixed Lineage Leukemia (Menin-MLL) Protein-Protein Interaction.[J Med Chem. 2019]Structure-Based Discovery of M-89 as a Highly Potent Inhibitor of the Menin-Mixed Lineage Leukemia (Menin-MLL) Protein-Protein Interaction.Aguilar A, Zheng K, Xu T, Xu S, Huang L, Fernandez-Salas E, Liu L, Bernard D, Harvey KP, Foster C, et al. J Med Chem. 2019 Jul 11; 62(13):6015-6034. Epub 2019 Jun 22.
- Identification of novel small-molecule inhibitors targeting menin-MLL interaction, repurposing the antidiarrheal loperamide.[Org Biomol Chem. 2016]Identification of novel small-molecule inhibitors targeting menin-MLL interaction, repurposing the antidiarrheal loperamide.Yue L, Du J, Ye F, Chen Z, Li L, Lian F, Zhang B, Zhang Y, Jiang H, Chen K, et al. Org Biomol Chem. 2016 Sep 28; 14(36):8503-19. Epub 2016 Aug 19.
- Progress towards small molecule menin-mixed lineage leukemia (MLL) interaction inhibitors with in vivo utility.[Bioorg Med Chem Lett. 2015]Progress towards small molecule menin-mixed lineage leukemia (MLL) interaction inhibitors with in vivo utility.Senter T, Gogliotti RD, Han C, Locuson CW, Morrison R, Daniels JS, Cierpicki T, Grembecka J, Lindsley CW, Stauffer SR. Bioorg Med Chem Lett. 2015 Jul 1; 25(13):2720-5. Epub 2015 Apr 25.
- Review Menin-MLL protein-protein interaction inhibitors: a patent review (2021-present).[Expert Opin Ther Pat. 2024]Review Menin-MLL protein-protein interaction inhibitors: a patent review (2021-present).Wang F, Yang Z, Wu Y, Bai H, Xin M. Expert Opin Ther Pat. 2024 Nov 3; :1-14. Epub 2024 Nov 3.
- Figure 11, Ancillary and DMPK Profiles of ML227 Enantiomers - Probe Reports from...Figure 11, Ancillary and DMPK Profiles of ML227 Enantiomers - Probe Reports from the NIH Molecular Libraries Program
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